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Physiologically based pharmacokinetic modeling of tacrolimus for food-drug and CYP3A drug-drug-gene interaction predictions.
CPT Pharmacometrics Syst Pharmacol. 2023 May;12(5):724-738. doi: 10.1002/psp4.12946. Epub 2023 Mar 10.
CPT Pharmacometrics Syst Pharmacol. 2023.
PMID: 36808892
Free PMC article.
Physiologically-based pharmacokinetic modeling of quinidine to establish a CYP3A4, P-gp, and CYP2D6 drug-drug-gene interaction network.
Feick D, Rüdesheim S, Marok FZ, Selzer D, Loer HLH, Teutonico D, Frechen S, van der Lee M, Moes DJAR, Swen JJ, Schwab M, Lehr T.
Feick D, et al. Among authors: loer hlh.
CPT Pharmacometrics Syst Pharmacol. 2023 Aug;12(8):1143-1156. doi: 10.1002/psp4.12981. Epub 2023 May 23.
CPT Pharmacometrics Syst Pharmacol. 2023.
PMID: 37165978
Free PMC article.
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Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug-Drug-Gene Interaction Predictions.
Loer HLH, Türk D, Gómez-Mantilla JD, Selzer D, Lehr T.
Loer HLH, et al.
Pharmaceutics. 2022 Apr 22;14(5):915. doi: 10.3390/pharmaceutics14050915.
Pharmaceutics. 2022.
PMID: 35631502
Free PMC article.
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Physiologically based pharmacokinetic modeling of imatinib and N-desmethyl imatinib for drug-drug interaction predictions.
Loer HLH, Kovar C, Rüdesheim S, Marok FZ, Fuhr LM, Selzer D, Schwab M, Lehr T.
Loer HLH, et al.
CPT Pharmacometrics Syst Pharmacol. 2024 Mar 14. doi: 10.1002/psp4.13127. Online ahead of print.
CPT Pharmacometrics Syst Pharmacol. 2024.
PMID: 38482980
Free article.
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