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Showing results for heiko taken
Search for Heiko Tapken instead (1 results)
Monkeypox in Germany.
Hoffmann C, Jessen H, Boesecke C. Hoffmann C, et al. Dtsch Arztebl Int. 2022 Aug 22;119(33-34):551-557. doi: 10.3238/arztebl.m2022.0287. Dtsch Arztebl Int. 2022. PMID: 35912445 Free PMC article.
The most common general symptoms were fever, headache, limb pain, and, often, painfully swollen lymph nodes. Most infections to date have taken a relatively mild course: 5.0% of the patients were hospitalized, and none died. ...
The most common general symptoms were fever, headache, limb pain, and, often, painfully swollen lymph nodes. Most infections to date have …
β-Cell Maturation and Identity in Health and Disease.
Salinno C, Cota P, Bastidas-Ponce A, Tarquis-Medina M, Lickert H, Bakhti M. Salinno C, et al. Int J Mol Sci. 2019 Oct 30;20(21):5417. doi: 10.3390/ijms20215417. Int J Mol Sci. 2019. PMID: 31671683 Free PMC article. Review.
The loss or dysfunction of insulin-producing beta-cells, in patients with type 1 and type 2 diabetes respectively, put these cells at the center of the disease initiation and progression. Therefore, major efforts have been taken to restore the beta-cell mass by cell-replac …
The loss or dysfunction of insulin-producing beta-cells, in patients with type 1 and type 2 diabetes respectively, put these cells at the ce …
Patterns of synaptic loss in human amyotrophic lateral sclerosis spinal cord: a clinicopathological study.
Aousji O, Feldengut S, Antonucci S, Schön M, Boeckers TM, Matschke J, Mawrin C, Ludolph AC, Del Tredici K, Roselli F, Braak H. Aousji O, et al. Acta Neuropathol Commun. 2023 Jul 25;11(1):120. doi: 10.1186/s40478-023-01616-8. Acta Neuropathol Commun. 2023. PMID: 37491361 Free PMC article.
The amount of synaptic loss was predicted by disease duration, by the clinical site of onset, and by the loss of alpha-motoneurons, although not by the fraction of pTDP-43-immunopositive alpha-motoneurons. Taken together, our findings validate the synaptic pathology observ …
The amount of synaptic loss was predicted by disease duration, by the clinical site of onset, and by the loss of alpha-motoneurons, although …
Inceptor correlates with markers of prostate cancer progression and modulates insulin/IGF1 signaling and cancer cell migration.
Wissmiller K, Bilekova S, Franko A, Lutz SZ, Katsburg M, Gulde S, Pellegata NS, Stenzl A, Heni M, Berti L, Häring HU, Lickert H. Wissmiller K, et al. Mol Metab. 2023 May;71:101706. doi: 10.1016/j.molmet.2023.101706. Epub 2023 Mar 15. Mol Metab. 2023. PMID: 36931467 Free PMC article.
In human samples, inceptor expression was significantly correlated with markers of prostate cancer progression. Taken together, these data provide a basis for investigation of inceptor in the context of prostate cancer....
In human samples, inceptor expression was significantly correlated with markers of prostate cancer progression. Taken together, these …
14-3-3σ Functions as an Intestinal Tumor Suppressor.
Winter M, Rokavec M, Hermeking H. Winter M, et al. Cancer Res. 2021 Jul 1;81(13):3621-3634. doi: 10.1158/0008-5472.CAN-20-4192. Epub 2021 Jun 15. Cancer Res. 2021. PMID: 34224368
The transcriptional programs controlled by the 14-3-3sigma-interacting factors SNAIL, c-JUN, YAP1, and FOXO1 were activated by deletion of 14-3-3sigma, potentially contributing to the enhanced tumor formation and growth. Taken together, these results provide genetic eviden …
The transcriptional programs controlled by the 14-3-3sigma-interacting factors SNAIL, c-JUN, YAP1, and FOXO1 were activated by deletion of 1 …
Heparin-binding protein in ventilator-induced lung injury.
Tydén J, Larsson N, Lehtipalo S, Herwald H, Hultin M, Walldén J, Behndig AF, Johansson J. Tydén J, et al. Intensive Care Med Exp. 2018 Sep 10;6(1):33. doi: 10.1186/s40635-018-0198-x. Intensive Care Med Exp. 2018. PMID: 30203380 Free PMC article.
METHODS: Anaesthetized pigs were randomized to receive ventilation with either tidal volumes of 8 ml/kg (controls, n = 6) or 20 ml/kg (VILI group, n = 6). Plasma and BALF samples were taken at 0, 1, 2, 4, and 6 h. In humans, HBP levels in BALF were sampled from 16 healthy …
METHODS: Anaesthetized pigs were randomized to receive ventilation with either tidal volumes of 8 ml/kg (controls, n = 6) or 20 ml/kg (VILI …
Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs and c-MYC DNA-Binding by Next-Generation Sequencing.
Jackstadt R, Kaller M, Menssen A, Hermeking H. Jackstadt R, et al. Methods Mol Biol. 2021;2318:119-160. doi: 10.1007/978-1-0716-1476-1_7. Methods Mol Biol. 2021. PMID: 34019289
Furthermore, we describe the validation of single c-MYC targets identified by NGS . Taken together, these approaches allow an accelerated and comprehensive analysis of c-MYC function in numerous cellular contexts. ...
Furthermore, we describe the validation of single c-MYC targets identified by NGS . Taken together, these approaches allow an acceler …
[Coagulation management in the treatment of multiple trauma].
Lier H, Krep H, Schöchl H. Lier H, et al. Anaesthesist. 2009 Oct;58(10):1010-26. doi: 10.1007/s00101-009-1595-z. Anaesthesist. 2009. PMID: 19816662 Review. German.
For thrombocytopathic patients with diffuse bleeding desmopressin (DDAVP) is a therapeutic option and the "off label" use of recombinant activated factor VIIa (rFVIIa) remains an option for individual situations with stringent indications and when the above named measures to opti …
For thrombocytopathic patients with diffuse bleeding desmopressin (DDAVP) is a therapeutic option and the "off label" use of recombinant act …
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
Böttcher A, Büttner M, Tritschler S, Sterr M, Aliluev A, Oppenländer L, Burtscher I, Sass S, Irmler M, Beckers J, Ziegenhain C, Enard W, Schamberger AC, Verhamme FM, Eickelberg O, Theis FJ, Lickert H. Böttcher A, et al. Nat Cell Biol. 2021 Jan;23(1):23-31. doi: 10.1038/s41556-020-00617-2. Epub 2021 Jan 4. Nat Cell Biol. 2021. PMID: 33398177
Finally, Wnt/PCP-activated Lgr5(+) ISCs are molecularly indistinguishable from Wnt/beta-catenin-activated Lgr5(+) ISCs, suggesting that lineage priming and cell-cycle exit is triggered at the post-transcriptional level by polarity cues and a switch from canonical to non-canonical …
Finally, Wnt/PCP-activated Lgr5(+) ISCs are molecularly indistinguishable from Wnt/beta-catenin-activated Lgr5(+) ISCs, suggesting that line …
Generation of a human induced pluripotent stem cell line (HMGUi002-A) from a healthy male individual.
Wang X, Malinowski AR, Beckenbauer J, Siehler J, Blöchinger A, Meitinger T, Häring HU, Staiger H, Burtscher I, Lickert H. Wang X, et al. Stem Cell Res. 2019 Aug;39:101531. doi: 10.1016/j.scr.2019.101531. Epub 2019 Aug 7. Stem Cell Res. 2019. PMID: 31419739 Free article.
Furthermore, we show that this iPSC line can be differentiated into pancreatic lineage cells. Taken together, this iPSC line will be useful to test differentiation protocols towards beta-cell as well as other cell types and will also serve as a control for drug development …
Furthermore, we show that this iPSC line can be differentiated into pancreatic lineage cells. Taken together, this iPSC line will be …
37 results