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Showing results for hearing jo
Search for Hearin Jo instead (1 results)
100,000 Genomes Pilot on Rare-Disease Diagnosis in Health Care - Preliminary Report.
100,000 Genomes Project Pilot Investigators; Smedley D, Smith KR, Martin A, Thomas EA, McDonagh EM, Cipriani V, Ellingford JM, Arno G, Tucci A, Vandrovcova J, Chan G, Williams HJ, Ratnaike T, Wei W, Stirrups K, Ibanez K, Moutsianas L, Wielscher M, Need A, Barnes MR, Vestito L, Buchanan J, Wordsworth S, Ashford S, Rehmström K, Li E, Fuller G, Twiss P, Spasic-Boskovic O, Halsall S, Floto RA, Poole K, Wagner A, Mehta SG, Gurnell M, Burrows N, James R, Penkett C, Dewhurst E, Gräf S, Mapeta R, Kasanicki M, Haworth A, Savage H, Babcock M, Reese MG, Bale M, Baple E, Boustred C, Brittain H, de Burca A, Bleda M, Devereau A, Halai D, Haraldsdottir E, Hyder Z, Kasperaviciute D, Patch C, Polychronopoulos D, Matchan A, Sultana R, Ryten M, Tavares ALT, Tregidgo C, Turnbull C, Welland M, Wood S, Snow C, Williams E, Leigh S, Foulger RE, Daugherty LC, Niblock O, Leong IUS, Wright CF, Davies J, Crichton C, Welch J, Woods K, Abulhoul L, Aurora P, Bockenhauer D, Broomfield A, Cleary MA, Lam T, Dattani M, Footitt E, Ganesan V, Grunewald S, Compeyrot-Lacassagne S, Muntoni F, Pilkington C, Quinlivan R, Thapar N, Wallis C, Wedderburn LR, Worth A, Bueser T, Compton C, Deshpande C, Fassihi H, Haque E, Izat… See abstract for full author list ➔ 100,000 Genomes Project Pilot Investigators, et al. N Engl J Med. 2021 Nov 11;385(20):1868-1880. doi: 10.1056/NEJMoa2035790. N Engl J Med. 2021. PMID: 34758253 Free PMC article.
Diagnostic yields were much higher for disorders likely to have a monogenic cause (35%) than for disorders likely to have a complex cause (11%). Diagnostic yields for intellectual disability, hearing disorders, and vision disorders ranged from 40 to 55%. We made genetic di …
Diagnostic yields were much higher for disorders likely to have a monogenic cause (35%) than for disorders likely to have a complex cause (1 …
Hearing molecules, mechanism and transportation: modeled in Drosophila melanogaster.
Bokolia NP, Mishra M. Bokolia NP, et al. Dev Neurobiol. 2015 Feb;75(2):109-30. doi: 10.1002/dneu.22221. Epub 2014 Aug 5. Dev Neurobiol. 2015. PMID: 25081222 Review.
The mechanical signals exist in the environment are resensed by the specialized mechanosensory cells, which convert the external forces into the electrical signals. Hearing is a magnificent example that relies on the mechanotransduction mediated by the auditory cells, for …
The mechanical signals exist in the environment are resensed by the specialized mechanosensory cells, which convert the external forces into …
Aminoglycoside treatment alters hearing-related genes and depicts behavioral defects in Drosophila.
Dhar G, Paikra SK, Mishra M. Dhar G, et al. Arch Insect Biochem Physiol. 2022 May;110(1):e21871. doi: 10.1002/arch.21871. Epub 2022 Feb 12. Arch Insect Biochem Physiol. 2022. PMID: 35150449
The hearing organ of Drosophila (Johnston's organ [JO]) shares much structural, developmental, and functional similarity with the vertebrate hearing organ (Organ of Corti). JO is evolving as a potential model system to examine the hearing-associ …
The hearing organ of Drosophila (Johnston's organ [JO]) shares much structural, developmental, and functional similarity with …
Management of Juvenile Otosclerosis: A Systematic Review.
Fancello V, Sacchetto L, Bianchini C, Ciorba A, Monzani D, Palma S. Fancello V, et al. Children (Basel). 2022 Nov 21;9(11):1787. doi: 10.3390/children9111787. Children (Basel). 2022. PMID: 36421236 Free PMC article. Review.
Otosclerosis can occur during childhood, resulting in the early onset of conductive hearing loss. The approach to a child with otosclerosis can present some difficulties in terms of diagnosis and treatment, and the literature on juvenile otosclerosis (JO) is still r …
Otosclerosis can occur during childhood, resulting in the early onset of conductive hearing loss. The approach to a child with otoscl …
A nonneural miRNA cluster mediates hearing via repression of two neural targets.
Zhang B, Duan H, Kavaler J, Wei L, Eberl DF, Lai EC. Zhang B, et al. Genes Dev. 2023 Dec 26;37(21-24):1041-1051. doi: 10.1101/gad.351052.123. Genes Dev. 2023. PMID: 38110249 Free PMC article.
We show here that mir-279/996 are absolutely essential for development and function of Johnston's organ (JO), the primary proprioceptive and auditory organ in Drosophila Their deletion results in highly aberrant cell fate determination, including loss of scolopale cells an …
We show here that mir-279/996 are absolutely essential for development and function of Johnston's organ (JO), the primary propriocept …
Percutaneous Bone-Anchored Hearing Implant: Is It Clinically Useful in Korean?
Koh SM, Cho YS, Kim GY, Jo M, Seol HY, Moon IJ. Koh SM, et al. J Korean Med Sci. 2022 Jun 13;37(23):e182. doi: 10.3346/jkms.2022.37.e182. J Korean Med Sci. 2022. PMID: 35698836 Free PMC article.
Standardized questionnaires, the Hearing Handicap Inventory for the Elderly (HHIE) and Speech, Spatial and Qualities of Hearing Scale (SSQ), were administered. ...The total score for HHIE decreased significantly (Z = -3.130, P = 0.002) while the SSQ score increased …
Standardized questionnaires, the Hearing Handicap Inventory for the Elderly (HHIE) and Speech, Spatial and Qualities of Hearing …
Music Perception Abilities of the Hearing Amplification System Users.
Jo S, Yun J, Kyong JS, Shin Y, Kim J. Jo S, et al. J Audiol Otol. 2023 Apr;27(2):78-87. doi: 10.7874/jao.2022.00367. Epub 2023 Mar 13. J Audiol Otol. 2023. PMID: 36907203 Free PMC article.
BACKGROUND AND OBJECTIVES: Recently, the improvement of music perception abilities for emotional stability and high quality of life has become important for the hearing loss group. This study aimed to examine and compare the music perception abilities of the normal hear …
BACKGROUND AND OBJECTIVES: Recently, the improvement of music perception abilities for emotional stability and high quality of life has beco …
Hearing and Speech Perception for People With Hearing Loss Using Personal Sound Amplification Products.
Kim GY, Kim S, Jo M, Seol HY, Cho YS, Lim J, Moon IJ. Kim GY, et al. J Korean Med Sci. 2022 Mar 28;37(12):e94. doi: 10.3346/jkms.2022.37.e94. J Korean Med Sci. 2022. PMID: 35347902 Free PMC article.
This study aimed to evaluate the clinical efficacy of PSAPs in patients with mild to moderately severe HL. METHODS: Nineteen patients with mild hearing loss (MHL), 23 with moderate hearing loss (MDHL), and 15 with moderately severe hearing loss (MSHL) partici …
This study aimed to evaluate the clinical efficacy of PSAPs in patients with mild to moderately severe HL. METHODS: Nineteen patients with m …
Juvenile otosclerosis and congenital stapes footplate fixation. A systematic review and meta-analysis of surgical outcomes and management.
Daniel A, Budiono G, Rao A, Low GK, Ellis MP, Lee J. Daniel A, et al. Int J Pediatr Otorhinolaryngol. 2023 Mar;166:111418. doi: 10.1016/j.ijporl.2022.111418. Epub 2022 Dec 30. Int J Pediatr Otorhinolaryngol. 2023. PMID: 36709714 Review.
The reported number of dead ears was 4/473 (0.8%) for JO and 2/337 (0.6%) for CSFF. 23 cases (2.8%) reported sensorineural hearing loss (SNHL) >10 dB. CONCLUSION: CSFF was associated with poorer hearing outcomes compared to JO, however both entities …
The reported number of dead ears was 4/473 (0.8%) for JO and 2/337 (0.6%) for CSFF. 23 cases (2.8%) reported sensorineural hearing …
Mechanosensory neuron regeneration in adult Drosophila.
Fernández-Hernández I, Marsh EB, Bonaguidi MA. Fernández-Hernández I, et al. Development. 2021 Mar 10;148(5):dev187534. doi: 10.1242/dev.187534. Development. 2021. PMID: 33597190 Free PMC article.
New JO neurons develop cilia and target central brain circuitry. Unexpectedly, mitotic recombination clones point to JO neuron self-replication as a likely source of neuronal plasticity. ...Our findings introduce a new platform to expedite research on mechanisms and …
New JO neurons develop cilia and target central brain circuitry. Unexpectedly, mitotic recombination clones point to JO neuron …
125 results