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Page 1
Pharmacological selection of cannabinoid receptor effectors: Signalling, allosteric modulation and bias.
Neuropharmacology. 2021 Aug 1;193:108611. doi: 10.1016/j.neuropharm.2021.108611. Epub 2021 May 15.
Neuropharmacology. 2021.
PMID: 34000272
Review.
In Vitro Characterization of 6-Methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole (ZCZ011) at the Type 1 Cannabinoid Receptor: Allosteric Agonist or Allosteric Modulator?
Green HM, Finlay DB, Ross RA, Greig IR, Duffull SB, Glass M.
Green HM, et al.
ACS Pharmacol Transl Sci. 2022 Nov 22;5(12):1279-1291. doi: 10.1021/acsptsci.2c00160. eCollection 2022 Dec 9.
ACS Pharmacol Transl Sci. 2022.
PMID: 36524007
Free PMC article.
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Determination of the Cannabinoid CB1 Receptor's Positive Allosteric Modulator Binding Site through Mutagenesis Studies.
Green HM, Fellner DMJ, Finlay DB, Furkert DP, Glass M.
Green HM, et al.
Pharmaceuticals (Basel). 2024 Jan 24;17(2):154. doi: 10.3390/ph17020154.
Pharmaceuticals (Basel). 2024.
PMID: 38399369
Free PMC article.
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Insight into the mechanism of action of ORG27569 at the cannabinoid type one receptor utilising a unified mathematical model.
Green HM, Yang L, Zhu X, Finlay DB, Duffull SB, Glass M.
Green HM, et al.
Naunyn Schmiedebergs Arch Pharmacol. 2024 Jan 16. doi: 10.1007/s00210-023-02923-6. Online ahead of print.
Naunyn Schmiedebergs Arch Pharmacol. 2024.
PMID: 38227196
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A quantitative pharmacology model for cannabinoid CB1 receptor mediated by Gi/Gs protein competition.
Yang L, Finlay DB, Green HM, Zhu X, Glass M, Duffull S.
Yang L, et al. Among authors: green hm.
Br J Pharmacol. 2024 Apr;181(8):1324-1340. doi: 10.1111/bph.16293. Epub 2024 Jan 12.
Br J Pharmacol. 2024.
PMID: 38072805
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Positive allosteric modulation of the cannabinoid CB1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics.
Green HM, Manning JJ, Greig IR, Ross RA, Finlay DB, Glass M.
Green HM, et al.
Br J Pharmacol. 2024 Jun 3. doi: 10.1111/bph.16433. Online ahead of print.
Br J Pharmacol. 2024.
PMID: 38831545
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