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Diminazene Aceturate Reduces Angiotensin II Constriction and Interacts with the Spike Protein of Severe Acute Respiratory Syndrome Coronavirus 2.
Matsoukas JM, Gadanec LK, Zulli A, Apostolopoulos V, Kelaidonis K, Ligielli I, Moschovou K, Georgiou N, Plotas P, Chasapis CT, Moore G, Ridgway H, Mavromoustakos T. Matsoukas JM, et al. Among authors: ridgway h. Biomedicines. 2022 Jul 18;10(7):1731. doi: 10.3390/biomedicines10071731. Biomedicines. 2022. PMID: 35885036 Free PMC article.
Discovery of a new generation of angiotensin receptor blocking drugs: Receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2.
Ridgway H, Moore GJ, Mavromoustakos T, Tsiodras S, Ligielli I, Kelaidonis K, Chasapis CT, Gadanec LK, Zulli A, Apostolopoulos V, Petty R, Karakasiliotis I, Gorgoulis VG, Matsoukas JM. Ridgway H, et al. Comput Struct Biotechnol J. 2022;20:2091-2111. doi: 10.1016/j.csbj.2022.04.010. Epub 2022 Apr 9. Comput Struct Biotechnol J. 2022. PMID: 35432786 Free PMC article.
Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System.
Moore GJ, Ridgway H, Kelaidonis K, Chasapis CT, Ligielli I, Mavromoustakos T, Bojarska J, Matsoukas JM. Moore GJ, et al. Among authors: ridgway h. Molecules. 2022 Jul 29;27(15):4854. doi: 10.3390/molecules27154854. Molecules. 2022. PMID: 35956801 Free PMC article.
Computational and Enzymatic Studies of Sartans in SARS-CoV-2 Spike RBD-ACE2 Binding: The Role of Tetrazole and Perspectives as Antihypertensive and COVID-19 Therapeutics.
Kelaidonis K, Ligielli I, Letsios S, Vidali VP, Mavromoustakos T, Vassilaki N, Moore GJ, Hoffmann W, Węgrzyn K, Ridgway H, Chasapis CT, Matsoukas JM. Kelaidonis K, et al. Among authors: ridgway h. Int J Mol Sci. 2023 May 8;24(9):8454. doi: 10.3390/ijms24098454. Int J Mol Sci. 2023. PMID: 37176159 Free PMC article.
W254 in furin functions as a molecular gate promoting anti-viral drug binding: Elucidation of putative drug tunneling and docking by non-equilibrium molecular dynamics.
Ridgway H, Orbell JD, Matsoukas MT, Kelaidonis K, Moore GJ, Tsiodras S, Gorgoulis VG, Chasapis CT, Apostolopoulos V, Matsoukas JM. Ridgway H, et al. Comput Struct Biotechnol J. 2023 Sep 9;21:4589-4612. doi: 10.1016/j.csbj.2023.09.003. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 37817778 Free PMC article.
12 results