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Showing results for homing zeng
Your search for Haoming Zeng retrieved no results
Cell membrane coated-nanoparticles for cancer immunotherapy.
Zeng Y, Li S, Zhang S, Wang L, Yuan H, Hu F. Zeng Y, et al. Acta Pharm Sin B. 2022 Aug;12(8):3233-3254. doi: 10.1016/j.apsb.2022.02.023. Epub 2022 Feb 28. Acta Pharm Sin B. 2022. PMID: 35967284 Free PMC article. Review.
Cell membrane-coated nanoparticles (CMCNs) inherit abundant source cell-relevant functions, including "self" markers, cross-talking with the immune system, biological targeting, and homing to specific regions. These enable them to possess preferred characteristics, includi …
Cell membrane-coated nanoparticles (CMCNs) inherit abundant source cell-relevant functions, including "self" markers, cross-talking with the …
CDK4/6 inhibition triggers ICAM1-driven immune response and sensitizes LKB1 mutant lung cancer to immunotherapy.
Bai X, Guo ZQ, Zhang YP, Fan ZZ, Liu LJ, Liu L, Long LL, Ma SC, Wang J, Fang Y, Tang XR, Zeng YJ, Pan X, Wu DH, Dong ZY. Bai X, et al. Nat Commun. 2023 Mar 4;14(1):1247. doi: 10.1038/s41467-023-36892-4. Nat Commun. 2023. PMID: 36871040 Free PMC article.
Ectopic expression of Icam1 in Lkb1-deficient tumor increases homing and activation of adoptively transferred SIINFEKL-specific CD8(+) T cells, reactivates tumor-effector cell interactions and re-sensitises tumors to ICB. ...
Ectopic expression of Icam1 in Lkb1-deficient tumor increases homing and activation of adoptively transferred SIINFEKL-specific CD8(+ …
Cosmc controls B cell homing.
Zeng J, Eljalby M, Aryal RP, Lehoux S, Stavenhagen K, Kudelka MR, Wang Y, Wang J, Ju T, von Andrian UH, Cummings RD. Zeng J, et al. Nat Commun. 2020 Aug 10;11(1):3990. doi: 10.1038/s41467-020-17765-6. Nat Commun. 2020. PMID: 32778659 Free PMC article.
The molecular mechanisms regulating lymphocyte homing into lymph nodes are only partly understood. Here, we report that B cell-specific deletion of the X-linked gene, Cosmc, and the consequent decrease of protein O-glycosylation, induces developmental blocks of mouse B cel …
The molecular mechanisms regulating lymphocyte homing into lymph nodes are only partly understood. Here, we report that B cell-specif …
Tumor-Homing and Immune-Reprogramming Cellular Nanovesicles for Photoacoustic Imaging-Guided Phototriggered Precise Chemoimmunotherapy.
Fan Z, Wang Y, Li L, Zeng F, Shang Q, Liao Y, Liang C, Nie L. Fan Z, et al. ACS Nano. 2022 Oct 25;16(10):16177-16190. doi: 10.1021/acsnano.2c04983. Epub 2022 Sep 22. ACS Nano. 2022. PMID: 36136614
In this work, we synthesized engineered cellular nanovesicles (ECNVs) with tumor-homing and immune-reprogramming functions for photoacoustic (PA) imaging-guided precision chemoimmunotherapy. M1-macrophage-derived cellular nanovesicles (CNVs) were loaded with gold nanorods …
In this work, we synthesized engineered cellular nanovesicles (ECNVs) with tumor-homing and immune-reprogramming functions for photoa …
LRP12 is an endogenous transmembrane inactivator of α4 integrins.
Huang M, Lu L, Lin C, Zheng Y, Pan X, Wang S, Chen S, Zhang Y, Liu C, Ge G, Zeng YA, Chen J. Huang M, et al. Cell Rep. 2023 Jun 27;42(6):112667. doi: 10.1016/j.celrep.2023.112667. Epub 2023 Jun 17. Cell Rep. 2023. PMID: 37330909 Free article.
Knockdown of LRP12 leads to increased NAs and enhanced cell migration. Consistently, LRP12-deficient T cells show an enhanced homing capability in mice and lead to aggravated chronic colitis in a T cell-transfer colitis model. ...
Knockdown of LRP12 leads to increased NAs and enhanced cell migration. Consistently, LRP12-deficient T cells show an enhanced homing
Mechanisms and rejuvenation strategies for aged hematopoietic stem cells.
Li X, Zeng X, Xu Y, Wang B, Zhao Y, Lai X, Qian P, Huang H. Li X, et al. J Hematol Oncol. 2020 Apr 6;13(1):31. doi: 10.1186/s13045-020-00864-8. J Hematol Oncol. 2020. PMID: 32252797 Free PMC article. Review.
Hematopoietic stem cell (HSC) aging, which is accompanied by reduced self-renewal ability, impaired homing, myeloid-biased differentiation, and other defects in hematopoietic reconstitution function, is a hot topic in stem cell research. ...
Hematopoietic stem cell (HSC) aging, which is accompanied by reduced self-renewal ability, impaired homing, myeloid-biased differenti …
Functionally Improved Mesenchymal Stem Cells to Better Treat Myocardial Infarction.
Chen Z, Chen L, Zeng C, Wang WE. Chen Z, et al. Stem Cells Int. 2018 Nov 25;2018:7045245. doi: 10.1155/2018/7045245. eCollection 2018. Stem Cells Int. 2018. PMID: 30622568 Free PMC article. Review.
Mesenchymal stem cell (MSC) transplantation is considered a promising approach and has made significant progress in preclinical studies and clinical trials for treating MI. However, hurdles including poor survival, retention, homing, and differentiation capacity largely li …
Mesenchymal stem cell (MSC) transplantation is considered a promising approach and has made significant progress in preclinical studies and …
Allogeneic cord blood regulatory T cells can resolve lung inflammation.
Lyu MA, Huang M, Zeng K, Li L, Khoury JD, Nishimoto M, Ma H, Sadeghi T, Mukherjee S, Slutsky AS, Flowers CR, Parmar S. Lyu MA, et al. Cytotherapy. 2023 Mar;25(3):245-253. doi: 10.1016/j.jcyt.2022.10.009. Epub 2022 Nov 24. Cytotherapy. 2023. PMID: 36437190
RESULTS: Ex vivo-expanded UCB Tregs exhibited a unique phenotype with co-expression of CD45RA(+)CD45RO(+) >80% and lung homing markers, including CD49d. UCB Tregs did not turn pathogenic when exposed to IL-6. ...
RESULTS: Ex vivo-expanded UCB Tregs exhibited a unique phenotype with co-expression of CD45RA(+)CD45RO(+) >80% and lung homing mar …
Important role of the SDF-1/CXCR4 axis in the homing of systemically transplanted human amnion-derived mesenchymal stem cells (hAD-MSCs) to ovaries in rats with chemotherapy-induced premature ovarian insufficiency (POI).
Ling L, Hou J, Liu D, Tang D, Zhang Y, Zeng Q, Pan H, Fan L. Ling L, et al. Stem Cell Res Ther. 2022 Feb 23;13(1):79. doi: 10.1186/s13287-022-02759-6. Stem Cell Res Ther. 2022. PMID: 35197118 Free PMC article.
However, the cellular mechanisms that direct the migration and homing of hAD-MSCs to ovaries with chemotherapy-induced POI are incompletely understood. ...Moreover, inhibition of the PI3K/Akt signalling pathway significantly reduced the number of systemically transplanted …
However, the cellular mechanisms that direct the migration and homing of hAD-MSCs to ovaries with chemotherapy-induced POI are incomp …
108 results