Cosmc controls B cell homing.
Zeng J, Eljalby M, Aryal RP, Lehoux S, Stavenhagen K, Kudelka MR, Wang Y, Wang J, Ju T, von Andrian UH, Cummings RD.
Zeng J, et al.
Nat Commun. 2020 Aug 10;11(1):3990. doi: 10.1038/s41467-020-17765-6.
Nat Commun. 2020.
PMID: 32778659
Free PMC article.
The molecular mechanisms regulating lymphocyte homing into lymph nodes are only partly understood. Here, we report that B cell-specific deletion of the X-linked gene, Cosmc, and the consequent decrease of protein O-glycosylation, induces developmental blocks of mouse B cel …
The molecular mechanisms regulating lymphocyte homing into lymph nodes are only partly understood. Here, we report that B cell-specif …