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Showing results for homing yao
Your search for Haoming Yao retrieved no results
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging.
Mogilenko DA, Shpynov O, Andhey PS, Arthur L, Swain A, Esaulova E, Brioschi S, Shchukina I, Kerndl M, Bambouskova M, Yao Z, Laha A, Zaitsev K, Burdess S, Gillfilan S, Stewart SA, Colonna M, Artyomov MN. Mogilenko DA, et al. Immunity. 2021 Jan 12;54(1):99-115.e12. doi: 10.1016/j.immuni.2020.11.005. Epub 2020 Dec 2. Immunity. 2021. PMID: 33271118 Free article.
Taa cells were highly clonal, had specific epigenetic and transcriptional signatures, developed in response to an aged host environment, and expressed markers of exhaustion and tissue homing. Activated Taa cells were the primary source of GZMK, which enhanced inflammatory …
Taa cells were highly clonal, had specific epigenetic and transcriptional signatures, developed in response to an aged host environment, and …
DLL3 as an Emerging Target for the Treatment of Neuroendocrine Neoplasms.
Yao J, Bergsland E, Aggarwal R, Aparicio A, Beltran H, Crabtree JS, Hann CL, Ibrahim T, Byers LA, Sasano H, Umejiego J, Pavel M. Yao J, et al. Oncologist. 2022 Nov 3;27(11):940-951. doi: 10.1093/oncolo/oyac161. Oncologist. 2022. PMID: 35983951 Free PMC article. Review.
DISCUSSION: DLL3 is overexpressed in many NENs, implicated in tumor progression, and is typically associated with poor clinical outcomes, particularly in patients with NEC. Targeted therapies using DLL3 as a homing beacon for cytotoxic activity mediated via several differe …
DISCUSSION: DLL3 is overexpressed in many NENs, implicated in tumor progression, and is typically associated with poor clinical outcomes, pa …
Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses.
Druzd D, Matveeva O, Ince L, Harrison U, He W, Schmal C, Herzel H, Tsang AH, Kawakami N, Leliavski A, Uhl O, Yao L, Sander LE, Chen CS, Kraus K, de Juan A, Hergenhan SM, Ehlers M, Koletzko B, Haas R, Solbach W, Oster H, Scheiermann C. Druzd D, et al. Immunity. 2017 Jan 17;46(1):120-132. doi: 10.1016/j.immuni.2016.12.011. Epub 2017 Jan 10. Immunity. 2017. PMID: 28087238 Free PMC article.
Here, we show that lymphocyte migration through lymph nodes and lymph occurred in a non-continuous, circadian manner. Lymphocyte homing to lymph nodes peaked at night onset, with cells leaving the tissue during the day. ...
Here, we show that lymphocyte migration through lymph nodes and lymph occurred in a non-continuous, circadian manner. Lymphocyte homing …
Mesenchymal stem cell homing to improve therapeutic efficacy in liver disease.
Yuan M, Hu X, Yao L, Jiang Y, Li L. Yuan M, et al. Stem Cell Res Ther. 2022 May 3;13(1):179. doi: 10.1186/s13287-022-02858-4. Stem Cell Res Ther. 2022. PMID: 35505419 Free PMC article. Review.
A sufficient number of MSCs must be home to the target tissues after administration for successful application. However, inefficient homing of MSCs after systemic administration is a major limitation in MSC therapy. Here, we review the mechanisms and clinical application s …
A sufficient number of MSCs must be home to the target tissues after administration for successful application. However, inefficient homi …
VCAM-1(+) macrophages guide the homing of HSPCs to a vascular niche.
Li D, Xue W, Li M, Dong M, Wang J, Wang X, Li X, Chen K, Zhang W, Wu S, Zhang Y, Gao L, Chen Y, Chen J, Zhou BO, Zhou Y, Yao X, Li L, Wu D, Pan W. Li D, et al. Nature. 2018 Dec;564(7734):119-124. doi: 10.1038/s41586-018-0709-7. Epub 2018 Nov 19. Nature. 2018. PMID: 30455424 Free PMC article.
After HSPCs emerge from endothelial cells within the developing dorsal aorta, homing allows the nascent cells to anchor in their niches for further expansion and differentiation(2-5). ...These cells, named 'usher cells', together with caudal venous capillaries and plexus, …
After HSPCs emerge from endothelial cells within the developing dorsal aorta, homing allows the nascent cells to anchor in their nich …
Chitin-based hydrogel loaded with bFGF and SDF-1 for inducing endogenous mesenchymal stem cells homing to improve stress urinary incontinence.
Yang L, Xie F, Li Y, Lu Y, Li B, Hong S, Tang J, Liu J, Cheng J, He Y, Zhang Z, Zhang S, Chen M, Li L, Yao L, Yan S, Cai J, Hong L. Yang L, et al. Carbohydr Polym. 2023 Nov 1;319:121144. doi: 10.1016/j.carbpol.2023.121144. Epub 2023 Jun 29. Carbohydr Polym. 2023. PMID: 37567701 Free article.
In the later stage, it slowly releasing factors and promoting the homing of MSCs in vivo, which can improve the local microenvironment, increase collagen deposition, repair the tissue around urethra and finally improve SUI (Scheme 1). This is the first bold attempt in the …
In the later stage, it slowly releasing factors and promoting the homing of MSCs in vivo, which can improve the local microenvironmen …
Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice.
Sun L, Lv Z, Chen X, Ye R, Tian S, Wang C, Xie X, Yan L, Yao X, Shao Y, Cui S, Chen J, Liu J. Sun L, et al. Elife. 2024 Jan 25;12:RP89316. doi: 10.7554/eLife.89316. Elife. 2024. PMID: 38271475 Free PMC article.
Plzf, Id4, Setdb1, Stra8, Tial1/Tiar, Bcas2, Ddx5, Srsf10, Uhrf1, and Bud31) were bound by SRSF1 in the mouse testes. Specific deletion of Srsf1 in mouse germ cells impairs homing of precursor SSCs leading to male infertility. Whole-mount staining data showed the absence o …
Plzf, Id4, Setdb1, Stra8, Tial1/Tiar, Bcas2, Ddx5, Srsf10, Uhrf1, and Bud31) were bound by SRSF1 in the mouse testes. Specific deletion of S …
An ischemia-homing bioengineered nano-scavenger for specifically alleviating multiple pathogeneses in ischemic stroke.
Duan R, Sun K, Fang F, Wang N, He R, Gao Y, Jing L, Li Y, Gong Z, Yao Y, Luan T, Zhang C, Zhang J, Zhao Y, Xie H, Zhou Y, Teng J, Zhang J, Jia Y. Duan R, et al. J Nanobiotechnology. 2022 Aug 31;20(1):397. doi: 10.1186/s12951-022-01602-7. J Nanobiotechnology. 2022. PMID: 36045405 Free PMC article.
However, the performance of current therapeutic regimens is limited due to their poor target specificity, narrow therapeutic time window, and compromised therapeutic effect. To overcome these barriers, we designed an ischemia-homing bioengineered nano-scavenger by camoufla …
However, the performance of current therapeutic regimens is limited due to their poor target specificity, narrow therapeutic time window, an …
Role of selectins and their ligands in human implantation stage.
Feng Y, Ma X, Deng L, Yao B, Xiong Y, Wu Y, Wang L, Ma Q, Ma F. Feng Y, et al. Glycobiology. 2017 May 1;27(5):385-391. doi: 10.1093/glycob/cwx009. Glycobiology. 2017. PMID: 28115423 Review.
Selectins and their ligands are not only involved in physiological processes such as leukocyte homing and pathological processes such as cancer, but also play an essential role in the human implantation. ...
Selectins and their ligands are not only involved in physiological processes such as leukocyte homing and pathological processes such …
138 results