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Showing results for homing wan
Search for Haoming Wan instead (1 results)
Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients.
Zhang JL, Li YH, Wang LL, Liu HQ, Lu SY, Liu Y, Li K, Liu B, Li SY, Shao FM, Wang K, Sheng N, Li R, Cui JJ, Sun PC, Ma CX, Zhu B, Wang Z, Wan YH, Yu SS, Che Y, Wang CY, Wang C, Zhang Q, Zhao LM, Peng XZ, Cheng Z, Chang JB, Jiang JD. Zhang JL, et al. Signal Transduct Target Ther. 2021 Dec 6;6(1):414. doi: 10.1038/s41392-021-00835-6. Signal Transduct Target Ther. 2021. PMID: 34873151 Free PMC article.
Oral administration of FNC in rats revealed a substantial thymus-homing feature, with FNC triphosphate (the active form) concentrated in the thymus and peripheral blood mononuclear cells (PBMC). ...
Oral administration of FNC in rats revealed a substantial thymus-homing feature, with FNC triphosphate (the active form) concentrated …
Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment.
Wu Y, Wan S, Yang S, Hu H, Zhang C, Lai J, Zhou J, Chen W, Tang X, Luo J, Zhou X, Yu L, Wang L, Wu A, Fan Q, Wu J. Wu Y, et al. J Nanobiotechnology. 2022 Dec 27;20(1):542. doi: 10.1186/s12951-022-01746-6. J Nanobiotechnology. 2022. PMID: 36575429 Free PMC article. Review.
In this review, we have summarized the advances in the fabrication, characterization and homing capacity of macrophage membrane cloaking nanoparticles in various diseases, including cancers, immune diseases, cardiovascular diseases, central nervous system diseases, and mic …
In this review, we have summarized the advances in the fabrication, characterization and homing capacity of macrophage membrane cloak …
Neutrophil extracellular traps as a unique target in the treatment of chemotherapy-induced peripheral neuropathy.
Wang CY, Lin TT, Hu L, Xu CJ, Hu F, Wan L, Yang X, Wu XF, Zhang XT, Li Y, Yin HY, Jiang CY, Xin HL, Liu WT. Wang CY, et al. EBioMedicine. 2023 Apr;90:104499. doi: 10.1016/j.ebiom.2023.104499. Epub 2023 Mar 2. EBioMedicine. 2023. PMID: 36870200 Free PMC article.
IVIS Spectrum imaging and Laser Doppler Flow Metry are applied to explore the microcirculation hypoxia induced by NETs in the development of CIPN. Stroke Homing peptide (SHp)-guided deoxyribonuclease 1 (DNase1) is used to degrade NETs. ...
IVIS Spectrum imaging and Laser Doppler Flow Metry are applied to explore the microcirculation hypoxia induced by NETs in the development of …
Spermatogonial Stem Cell Transplantation in Large Animals.
Zhao X, Wan W, Zhang X, Wu Z, Yang H. Zhao X, et al. Animals (Basel). 2021 Mar 24;11(4):918. doi: 10.3390/ani11040918. Animals (Basel). 2021. PMID: 33805058 Free PMC article. Review.
This paper reviews the current knowledge on SSCT in large animals, addressing (1) donor spermatogonial stem cell (SSC) preparation, (2) recipient male treatment, and (3) SSC injection, homing, and detection. The major studies showing unequivocal evidence of donor SSC-deriv …
This paper reviews the current knowledge on SSCT in large animals, addressing (1) donor spermatogonial stem cell (SSC) preparation, (2) reci …
CAR T Cell Therapy: Remedies of Current Challenges in Design, Injection, Infiltration and Working.
Zhu Y, Feng J, Wan R, Huang W. Zhu Y, et al. Drug Des Devel Ther. 2023 Jun 14;17:1783-1792. doi: 10.2147/DDDT.S413348. eCollection 2023. Drug Des Devel Ther. 2023. PMID: 37337518 Free PMC article. Review.
We finally compared the influence of different injection methods on therapeutic efficacy. We also carefully explored the difficulties of designing, homing, and working of CAR T cells, and ultimately came up with better solutions for each process to help CAR T cells reach t …
We finally compared the influence of different injection methods on therapeutic efficacy. We also carefully explored the difficulties of des …
Targeted mRNA Nanoparticles Ameliorate Blood-Brain Barrier Disruption Postischemic Stroke by Modulating Microglia Polarization.
Gao M, Li Y, Ho W, Chen C, Chen Q, Li F, Tang M, Fan Q, Wan J, Yu W, Xu X, Li P, Zhang XQ. Gao M, et al. ACS Nano. 2024 Jan 30;18(4):3260-3275. doi: 10.1021/acsnano.3c09817. Epub 2024 Jan 16. ACS Nano. 2024. PMID: 38227975
By leveraging the pathological progression of an ischemic stroke, we developed an M2 microglia-targeting lipid nanoparticle (termed MLNP) approach that can selectively deliver mRNA encoding phenotype-switching interleukin-10 (mIL-10) to the ischemic brain, creating a beneficial f …
By leveraging the pathological progression of an ischemic stroke, we developed an M2 microglia-targeting lipid nanoparticle (termed MLNP) ap …
New therapeutic targets for cancer bone metastasis.
Krzeszinski JY, Wan Y. Krzeszinski JY, et al. Trends Pharmacol Sci. 2015 Jun;36(6):360-73. doi: 10.1016/j.tips.2015.04.006. Epub 2015 May 9. Trends Pharmacol Sci. 2015. PMID: 25962679 Free PMC article. Review.
This complicated process begins with the successful tumor cell epithelial-mesenchymal transition, escape from the original site, and penetration into the circulation. The homing of tumor cells to the bone depends on both tumor-intrinsic traits and various molecules supplie …
This complicated process begins with the successful tumor cell epithelial-mesenchymal transition, escape from the original site, and penetra …
Low-dose nicotine reduces the homing ability of murine BMSCs during fracture healing.
Zhang J, Wan Q, Yu X, Cheng G, Ni Y, Li Z. Zhang J, et al. Am J Transl Res. 2018 Sep 15;10(9):2796-2809. eCollection 2018. Am J Transl Res. 2018. PMID: 30323867 Free PMC article.
CCK8 test significantly increased at a high nicotine concentration of 1 mM while calcium nodule staining with Alizarin red decreased at the same concentration. In vitro scratch test, Transwell tests and in vivo BMSCs homing tests showed negative effects on BMSCs migration …
CCK8 test significantly increased at a high nicotine concentration of 1 mM while calcium nodule staining with Alizarin red decreased at the …
Roles of Dental Mesenchymal Stem Cells in the Management of Immature Necrotic Permanent Teeth.
Cui D, Yu S, Zhou X, Liu Y, Gan L, Pan Y, Zheng L, Wan M. Cui D, et al. Front Cell Dev Biol. 2021 May 19;9:666186. doi: 10.3389/fcell.2021.666186. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34095133 Free PMC article. Review.
Regeneration endodontics procedures (REPs) have been developed and considered as an alternative strategy for management of immature permanent teeth with pulpal necrosis, including cell-free and cell-based REPs. Cell-free REPs, including revascularization and cell homing wi …
Regeneration endodontics procedures (REPs) have been developed and considered as an alternative strategy for management of immature permanen …
Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment.
Huang X, Guo B, Liu S, Wan J, Broxmeyer HE. Huang X, et al. Nat Commun. 2018 Jul 16;9(1):2741. doi: 10.1038/s41467-018-05178-5. Nat Commun. 2018. PMID: 30013077 Free PMC article.
Enhancement of hematopoietic stem cell (HSC) homing and engraftment is clinically critical, especially for cord blood (CB) hematopoietic cell transplantation. ...Inhibition of nuclear factor-kappaB (NF-kappaB) signaling suppresses HDAC5-mediated CXCR4 upregulation, enhance …
Enhancement of hematopoietic stem cell (HSC) homing and engraftment is clinically critical, especially for cord blood (CB) hematopoie …
68 results