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A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo.
Chan JF, Oh YJ, Yuan S, Chu H, Yeung ML, Canena D, Chan CC, Poon VK, Chan CC, Zhang AJ, Cai JP, Ye ZW, Wen L, Yuen TT, Chik KK, Shuai H, Wang Y, Hou Y, Luo C, Chan WM, Qin Z, Sit KY, Au WK, Legendre M, Zhu R, Hain L, Seferovic H, Tampé R, To KK, Chan KH, Thomas DG, Klausberger M, Xu C, Moon JJ, Stadlmann J, Penninger JM, Oostenbrink C, Hinterdorfer P, Yuen KY, Markovitz DM. Chan JF, et al. Among authors: seferovic h. Cell Rep Med. 2022 Oct 18;3(10):100774. doi: 10.1016/j.xcrm.2022.100774. Epub 2022 Sep 29. Cell Rep Med. 2022. PMID: 36195094 Free PMC article.
Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level.
Zhu R, Canena D, Sikora M, Klausberger M, Seferovic H, Mehdipour AR, Hain L, Laurent E, Monteil V, Wirnsberger G, Wieneke R, Tampé R, Kienzl NF, Mach L, Mirazimi A, Oh YJ, Penninger JM, Hummer G, Hinterdorfer P. Zhu R, et al. Among authors: seferovic h. Nat Commun. 2022 Dec 24;13(1):7926. doi: 10.1038/s41467-022-35641-3. Nat Commun. 2022. PMID: 36566234 Free PMC article.
Author Correction: Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level.
Zhu R, Canena D, Sikora M, Klausberger M, Seferovic H, Mehdipour AR, Hain L, Laurent E, Monteil V, Wirnsberger G, Wieneke R, Tampé R, Kienzl NF, Mach L, Mirazimi A, Oh YJ, Penninger JM, Hummer G, Hinterdorfer P. Zhu R, et al. Among authors: seferovic h. Nat Commun. 2023 Feb 28;14(1):1142. doi: 10.1038/s41467-023-36905-2. Nat Commun. 2023. PMID: 36854739 Free PMC article. No abstract available.