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A potent and selective CXCR2 antagonist improves neuroimmune dysregulation through the inhibition of NF-κB and notch inflammatory signaling in the BTBR mouse model of autism.
Alomar HA, Ansari MA, Nadeem A, Attia SM, Bakheet SA, Al-Mazroua HA, Hussein MH, Alqarni SA, Ahmad SF. Alomar HA, et al. Among authors: al mazroua ha. J Neuroimmunol. 2023 Apr 15;377:578069. doi: 10.1016/j.jneuroim.2023.578069. Epub 2023 Mar 10. J Neuroimmunol. 2023. PMID: 36931207
Histamine H4 Receptor Antagonist Ameliorates the Progression of Experimental Autoimmune Encephalomyelitis via Regulation of T-Cell Imbalance.
Aldossari AA, Assiri MA, Ansari MA, Nadeem A, Attia SM, Bakheet SA, Albekairi TH, Alomar HA, Al-Mazroua HA, Almanaa TN, Al-Hamamah MA, Alwetaid MY, Ahmad SF. Aldossari AA, et al. Among authors: al mazroua ha. Int J Mol Sci. 2023 Oct 17;24(20):15273. doi: 10.3390/ijms242015273. Int J Mol Sci. 2023. PMID: 37894952 Free PMC article.
S3I-201, a selective stat3 inhibitor, ameliorates clinical symptoms in a mouse model of experimental autoimmune encephalomyelitis through the regulation of multiple intracellular signalling in Th1, Th17, and treg cells.
Ahmad SF, Ansari MA, Nadeem A, Bakheet SA, Al-Mazroua HA, Alomar HA, Al-Hamamah MA, Attia SM. Ahmad SF, et al. Among authors: al mazroua ha. Mult Scler Relat Disord. 2023 May;73:104658. doi: 10.1016/j.msard.2023.104658. Epub 2023 Mar 23. Mult Scler Relat Disord. 2023. PMID: 36989705
Lead (Pb) exposure exacerbates behavioral and immune abnormalities by upregulating Th17 and NF-κB-related signaling in BTBR T+ Itpr3tf/J autistic mouse model.
Almutairi MM, Nadeem A, Ansari MA, Bakheet SA, Attia SM, Albekairi TH, Alhosaini K, Algahtani M, Alsaad AMS, Al-Mazroua HA, Ahmad SF. Almutairi MM, et al. Among authors: al mazroua ha. Neurotoxicology. 2022 Jul;91:340-348. doi: 10.1016/j.neuro.2022.06.007. Epub 2022 Jun 26. Neurotoxicology. 2022. PMID: 35760230
Cathepsin B inhibitor alleviates Th1, Th17, and Th22 transcription factor signaling dysregulation in experimental autoimmune encephalomyelitis.
Ansari MA, Nadeem A, Alshammari MA, Attia SM, Bakheet SA, Khan MR, Albekairi TH, Alasmari AF, Alhosaini K, Alqahtani F, Al-Mazroua HA, Ahmad SF. Ansari MA, et al. Among authors: al mazroua ha. Exp Neurol. 2022 May;351:113997. doi: 10.1016/j.expneurol.2022.113997. Epub 2022 Feb 2. Exp Neurol. 2022. PMID: 35122866
25 results