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Showing results for hae i ii
Search for Hae-Ri Wi instead (2 results)
Hereditary angioedema: Pathophysiology (HAE type I, HAE type II, and HAE nC1-INH).
Wedner HJ. Wedner HJ. Allergy Asthma Proc. 2020 Nov 1;41(Suppl 1):S14-S17. doi: 10.2500/aap.2020.41.200081. Allergy Asthma Proc. 2020. PMID: 33109319 Review.
The pathophysiology of hereditary angioedema (HAE) in virtually all cases is the result of the uncontrolled production of the vasoactive peptide bradykinin. ...Failure to adequately control the production of bradykinin is thus the major mechanism for HAE. Several ot …
The pathophysiology of hereditary angioedema (HAE) in virtually all cases is the result of the uncontrolled production of the vasoact …
Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology.
Sinnathamby ES, Issa PP, Roberts L, Norwood H, Malone K, Vemulapalli H, Ahmadzadeh S, Cornett EM, Shekoohi S, Kaye AD. Sinnathamby ES, et al. Adv Ther. 2023 Mar;40(3):814-827. doi: 10.1007/s12325-022-02401-0. Epub 2023 Jan 7. Adv Ther. 2023. PMID: 36609679 Free PMC article. Review.
HAE affects 1/50,000 people worldwide. Three main types of HAE exist: type I, type II, and type III. ...C1-INH is important in the coagulation complement, contact systems, and fibrinolysis. Most HAE cases are type I. Type I and II HAE res
HAE affects 1/50,000 people worldwide. Three main types of HAE exist: type I, type II, and type III. ...C1-INH is impor
Interventions for the long-term prevention of hereditary angioedema attacks.
Beard N, Frese M, Smertina E, Mere P, Katelaris C, Mills K. Beard N, et al. Cochrane Database Syst Rev. 2022 Nov 3;11(11):CD013403. doi: 10.1002/14651858.CD013403.pub2. Cochrane Database Syst Rev. 2022. PMID: 36326435 Free PMC article. Review.
People with Type I HAE (approximately 80% of all HAE cases) have insufficient amounts of C1 esterase inhibitor (C1-INH) protein; people with Type II HAE (approximately 20% of all cases) may have normal C1-INH concentrations, but, due to genetic mutatio …
People with Type I HAE (approximately 80% of all HAE cases) have insufficient amounts of C1 esterase inhibitor (C1-INH) protei …
Bradykinin-mediated diseases.
Kaplan AP. Kaplan AP. Chem Immunol Allergy. 2014;100:140-7. doi: 10.1159/000358619. Epub 2014 May 22. Chem Immunol Allergy. 2014. PMID: 24925394 Review.
Most cases have an IgG autoantibody to C1 inhibitor which inactivates it so that the presentation is strikingly similar to type I HAE. New therapies for types I and II HAE include C1 inhibitor replacement therapy, ecallantide, a kallikrein antagonist, and ica …
Most cases have an IgG autoantibody to C1 inhibitor which inactivates it so that the presentation is strikingly similar to type I HAE
Lanadelumab: First Global Approval.
Syed YY. Syed YY. Drugs. 2018 Oct;78(15):1633-1637. doi: 10.1007/s40265-018-0987-2. Drugs. 2018. PMID: 30267321 Review.
Shire is developing lanadelumab (Takhzyro) for the prevention of hereditary angioedema (HAE) attacks. Lanadelumab is a fully human monoclonal antibody that inhibits plasma kallikrein. ...Subcutaneous administration of lanadelumab significantly reduced HAE attacks ve …
Shire is developing lanadelumab (Takhzyro) for the prevention of hereditary angioedema (HAE) attacks. Lanadelumab is a fully human mo …
Investigational drugs in phase I and phase II clinical trials for hereditary angioedema.
Farkas H, Debreczeni ML, Kőhalmi KV. Farkas H, et al. Expert Opin Investig Drugs. 2018 Jan;27(1):87-103. doi: 10.1080/13543784.2018.1415325. Epub 2017 Dec 15. Expert Opin Investig Drugs. 2018. PMID: 29226721 Review.
By contrast, the investigational medicinal products under evaluation in Phase I and II clinical trials are targeted at the prevention of HAE attacks. ...This review summarizes the status and the findings of the currently ongoing Phase I and Phase II clinical …
By contrast, the investigational medicinal products under evaluation in Phase I and II clinical trials are targeted at the prevention …
Risk of angioedema following invasive or surgical procedures in HAE type I and II--the natural history.
Aygören-Pürsün E, Martinez Saguer I, Kreuz W, Klingebiel T, Schwabe D. Aygören-Pürsün E, et al. Allergy. 2013 Aug;68(8):1034-9. doi: 10.1111/all.12186. Allergy. 2013. PMID: 23968383 Free PMC article. Clinical Trial.
OBJECTIVES: This analysis examined rates of perioperative edema in patients with HAE not receiving prophylaxis. METHODS: This was a retrospective analysis of records of randomly selected patients with HAE type I or II treated at the Frankfurt Comprehensive Ca …
OBJECTIVES: This analysis examined rates of perioperative edema in patients with HAE not receiving prophylaxis. METHODS: This was a r …
The effects of DNA methylation by Hha I methylase on the cleavage reactions by Hae II, Aha II and Ban I endonucleases.
Kang SC, Choi WS, Yoo OJ. Kang SC, et al. Biochem Biophys Res Commun. 1987 May 29;145(1):482-7. doi: 10.1016/0006-291x(87)91346-5. Biochem Biophys Res Commun. 1987. PMID: 3036132
Considering that Hae II or Aha II methylase has not been isolated yet, the result explained above is a useful information for protecting a double stranded DNA from being cleaved by Hae II or Aha II endonuclease. In contrast to Hae
Considering that Hae II or Aha II methylase has not been isolated yet, the result explained above is a useful informati …
Pathophysiology of hereditary angioedema.
Zuraw BL, Christiansen SC. Zuraw BL, et al. Am J Rhinol Allergy. 2011 Nov-Dec;25(6):373-8. doi: 10.2500/ajra.2011.25.3661. Am J Rhinol Allergy. 2011. PMID: 22185738 Review.
METHODS: A literature review was conducted concerning the clinical characteristics and pathophysiology of types I and II hereditary angioedema (HAE), type III HAE, acquired C1 inhibitor (C1INH) deficiency, and angiotensin-converting enzyme (ACE) inhibitor-ass …
METHODS: A literature review was conducted concerning the clinical characteristics and pathophysiology of types I and II hereditary a …
Hereditary angioedema (HAE) in Belgium: results from a national survey.
Van der Poorten MM, Schrijvers R, Hermans C, Bartiaux M, Haerynck F, Lapeere H, Moutschen M, Michel O, Sabato V, Ebo DG, Van Gasse AL. Van der Poorten MM, et al. Front Allergy. 2023 May 26;4:1143897. doi: 10.3389/falgy.2023.1143897. eCollection 2023. Front Allergy. 2023. PMID: 37304167 Free PMC article.
METHODS: We set up a nation-wide, multicentric study involving the 8 Belgian hospitals known to follow-up patients with Type I and II HAE. All Belgium HAE patients were asked to fill out questionnaires that mainly covered demographic data, family history, and …
METHODS: We set up a nation-wide, multicentric study involving the 8 Belgian hospitals known to follow-up patients with Type I and II
593 results