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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 1
2006 1
2007 2
2008 2
2011 1
2013 1
2016 1
2019 2
2020 3
2021 5
2022 1
2023 7
2024 4

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32 results

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Page 1
Microbial peptides activate tumour-infiltrating lymphocytes in glioblastoma.
Naghavian R, Faigle W, Oldrati P, Wang J, Toussaint NC, Qiu Y, Medici G, Wacker M, Freudenmann LK, Bonté PE, Weller M, Regli L, Amigorena S, Rammensee HG, Walz JS, Brugger SD, Mohme M, Zhao Y, Sospedra M, Neidert MC, Martin R. Naghavian R, et al. Nature. 2023 May;617(7962):807-817. doi: 10.1038/s41586-023-06081-w. Epub 2023 May 17. Nature. 2023. PMID: 37198490 Free PMC article.
These peptides were also strongly stimulatory for bulk TILs and peripheral blood memory cells, which then respond to tumour-derived target peptides. Our data hint at how bacterial pathogens and bacterial gut microbiota can be involved in specific immune recognition of tumo …
These peptides were also strongly stimulatory for bulk TILs and peripheral blood memory cells, which then respond to tumour-derived target p …
Whipple disease.
Marth T, Schneider T. Marth T, et al. Curr Opin Gastroenterol. 2008 Mar;24(2):141-8. doi: 10.1097/MOG.0b013e3282f3f4f1. Curr Opin Gastroenterol. 2008. PMID: 18301263 Review.
The culture and subsequent genome analysis have led to improved diagnosis and monitoring of the disease, for example by PCR or immunohistochemistry. New experimental approaches hint of defects in T-cell and macrophage immunity in patients. Antibiotic therapy will soon be b …
The culture and subsequent genome analysis have led to improved diagnosis and monitoring of the disease, for example by PCR or immunohistoch …
Pharmacogenomics on the Treatment Response in Patients with Psoriasis: An Updated Review.
Wang CY, Wang CW, Chen CB, Chen WT, Chang YC, Hui RC, Chung WH. Wang CY, et al. Int J Mol Sci. 2023 Apr 15;24(8):7329. doi: 10.3390/ijms24087329. Int J Mol Sci. 2023. PMID: 37108492 Free PMC article. Review.
Genetic predisposition is known to contribute to the pathogenesis of psoriasis. Hence, pharmacogenomics gives the hint of predictive treatment response individually. This review highlights the current pharmacogenetic and pharmacogenomic studies of medical therapy in psoria …
Genetic predisposition is known to contribute to the pathogenesis of psoriasis. Hence, pharmacogenomics gives the hint of predictive …
Hyperuricemia remodels the serum proteome toward a higher inflammatory state.
Cabău G, Gaal O, Badii M, Nica V, Mirea AM, Hotea I; HINT-consortium; Pamfil C, Popp RA, Netea MG, Rednic S, Crișan TO, Joosten LAB. Cabău G, et al. iScience. 2023 Sep 14;26(10):107909. doi: 10.1016/j.isci.2023.107909. eCollection 2023 Oct 20. iScience. 2023. PMID: 37810213 Free PMC article.
Gut microbiota's causative relationship with peripheral artery disease: a Mendelian randomization study.
Tian Y, Yao G, Skudder-Hill L, Xu G, Qian Y, Tang F, Wang Q, Bao Q, Li L. Tian Y, et al. Front Microbiol. 2024 Mar 5;15:1340262. doi: 10.3389/fmicb.2024.1340262. eCollection 2024. Front Microbiol. 2024. PMID: 38505559 Free PMC article.
While traditional risk factors like smoking and hyperlipidemia are well-understood, our study aims to determine the potential causative association of gut microbiota with PAD using Mendelian Randomization. METHODS: Data from the International MiBioGen Consortium and the Fi …
While traditional risk factors like smoking and hyperlipidemia are well-understood, our study aims to determine the potential causative asso …
Precision Proteoform Design for 4R Tau Isoform Selective Templated Aggregation.
Longhini AP, DuBose A, Lobo S, Vijayan V, Bai Y, Rivera EK, Sala-Jarque J, Nikitina A, Carrettiero DC, Unger M, Sclafani O, Fu V, Vigers M, Buee L, Landrieu I, Shell S, Shea JE, Han S, Kosik KS. Longhini AP, et al. bioRxiv [Preprint]. 2023 Nov 28:2023.08.31.555649. doi: 10.1101/2023.08.31.555649. bioRxiv. 2023. PMID: 37693456 Free PMC article. Updated. Preprint.
These peptide fibrils function as partial prions to recruit naive 4R tau-ten times the length of the peptide-and serve as a critical template for 4R tauopathy propagation. These results hint at opportunities for tau isoform-specific therapeutic interventions....
These peptide fibrils function as partial prions to recruit naive 4R tau-ten times the length of the peptide-and serve as a critical templat …
Precision proteoform design for 4R tau isoform selective templated aggregation.
Longhini AP, DuBose A, Lobo S, Vijayan V, Bai Y, Rivera EK, Sala-Jarque J, Nikitina A, Carrettiero DC, Unger MT, Sclafani OR, Fu V, Beckett ER, Vigers M, Buée L, Landrieu I, Shell S, Shea JE, Han S, Kosik KS. Longhini AP, et al. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2320456121. doi: 10.1073/pnas.2320456121. Epub 2024 Apr 3. Proc Natl Acad Sci U S A. 2024. PMID: 38568974 Free PMC article.
These peptide fibrils function as partial prions to recruit naive 4R tau-ten times the length of the peptide-and serve as a critical template for 4R tauopathy propagation. These results hint at opportunities for tau isoform-specific therapeutic interventions....
These peptide fibrils function as partial prions to recruit naive 4R tau-ten times the length of the peptide-and serve as a critical templat …
From axiomatic systems to the Dogmatic gene and beyond.
Blanchard E, Longo G. Blanchard E, et al. Biosystems. 2021 Jun;204:104396. doi: 10.1016/j.biosystems.2021.104396. Epub 2021 Mar 13. Biosystems. 2021. PMID: 33722644
We expand on this sometimes fruitful confusion with some case studies. We then hint to the historical creation of sense as a component of an epistemology of mathematics. ...The analysis of the evolutionary production of variability, adaptivity and ecosystemic diversity is …
We expand on this sometimes fruitful confusion with some case studies. We then hint to the historical creation of sense as a componen …
Plasminogen as a prognostic biomarker for HBV-related acute-on-chronic liver failure.
Wu D, Zhang S, Xie Z, Chen E, Rao Q, Liu X, Huang K, Yang J, Xiao L, Ji F, Jiang Z, Zhao Y, Ouyang X, Zhu D, Dai X, Hou Z, Liu B, Deng B, Zhou N, Gao H, Sun Z, Li L. Wu D, et al. J Clin Invest. 2020 Apr 1;130(4):2069-2080. doi: 10.1172/JCI130197. J Clin Invest. 2020. PMID: 32175919 Free PMC article. Clinical Trial.
The P5 score, a prognostic panel incorporating plasminogen levels, hepatic encephalopathy occurrence, age, international normalized ratio (INR), and total bilirubin, was significantly superior to the Child-Pugh, Model for End-stage Liver Disease (MELD), Chronic Liver Failure C …
The P5 score, a prognostic panel incorporating plasminogen levels, hepatic encephalopathy occurrence, age, international normalized ratio (I …
An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor.
Zaidman D, Gehrtz P, Filep M, Fearon D, Gabizon R, Douangamath A, Prilusky J, Duberstein S, Cohen G, Owen CD, Resnick E, Strain-Damerell C, Lukacik P; Covid-Moonshot Consortium; Barr H, Walsh MA, von Delft F, London N. Zaidman D, et al. Cell Chem Biol. 2021 Dec 16;28(12):1795-1806.e5. doi: 10.1016/j.chembiol.2021.05.018. Epub 2021 Jun 25. Cell Chem Biol. 2021. PMID: 34174194 Free PMC article.
The docking was validated by 12 co-crystal structures. Together these examples hint at the vast number of covalent inhibitors accessible through our protocol....
The docking was validated by 12 co-crystal structures. Together these examples hint at the vast number of covalent inhibitors accessi …
32 results