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Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions.
Khanna N, Zhang Y, Lucas JS, Dudko OK, Murre C. Khanna N, et al. Nat Commun. 2019 Jun 24;10(1):2771. doi: 10.1038/s41467-019-10628-9. Nat Commun. 2019. PMID: 31235807 Free PMC article.
How such interactions are orchestrated remains unknown. Here we develop a strategy to track V(H)-D(H)J(H) motion in B-lymphocytes. We find that V(H) and D(H)J(H) segments are trapped in configurations that allow only local motion, such that spatially proximal segmen …
How such interactions are orchestrated remains unknown. Here we develop a strategy to track V(H)-D(H)J(H) motion in B-lymphocy …
Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack.
Johnston SC, Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Jonasson J, Minematsu K, Molina CA, Wang Y, Wong KS; SOCRATES Steering Committee and Investigators. Johnston SC, et al. N Engl J Med. 2016 Jul 7;375(1):35-43. doi: 10.1056/NEJMoa1603060. Epub 2016 May 10. N Engl J Med. 2016. PMID: 27160892 Free article. Clinical Trial.
Long-lasting antinociceptive effects of green light in acute and chronic pain in rats.
Ibrahim MM, Patwardhan A, Gilbraith KB, Moutal A, Yang X, Chew LA, Largent-Milnes T, Malan TP, Vanderah TW, Porreca F, Khanna R. Ibrahim MM, et al. Pain. 2017 Feb;158(2):347-360. doi: 10.1097/j.pain.0000000000000767. Pain. 2017. PMID: 28092651 Free PMC article.
We investigated the effects of light-emitting diodes (LEDs), in the visible spectrum, on acute sensory thresholds in naive rats as well as in experimental neuropathic pain. Rats receiving green LED light (wavelength 525 nm, 8 h/d) showed significantly increased paw …
We investigated the effects of light-emitting diodes (LEDs), in the visible spectrum, on acute sensory thresholds in naive rats as well as i …
Preliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.
Kachapila M, Ademuyiwa AO, Biccard BM, Ghosh DN, Glasbey J, Monahan M, Moore R, Morton DG, Oppong R, Pearse R, Roberts TE; NIHR Global Health Research Unit on Global Surgery; ASOS Investigators; STARSurg Collaborative. Kachapila M, et al. PLoS One. 2021 Aug 12;16(8):e0254698. doi: 10.1371/journal.pone.0254698. eCollection 2021. PLoS One. 2021. PMID: 34383776 Free PMC article.
Advanced glycosylation end-products in diabetic rats on peritoneal dialysis using various solutions.
Lee JH, Reddy DK, Saran R, Moore HL, Twardowski ZJ, Nolph KD, Khanna R. Lee JH, et al. Perit Dial Int. 2000 Nov-Dec;20(6):643-51. Perit Dial Int. 2000. PMID: 11216553
Significant differences in D/D0 glucose and D/P urea were found between group C and group H (D/D0: 0.40 +/- 0.01 vs 0.35 +/- 0.01, p < 0.05; D/P urea: 0.87 +/- 0.03 vs 0.97 +/- 0.02, p < 0.05). ...
Significant differences in D/D0 glucose and D/P urea were found between group C and group H (D/D0: 0.40 +/- 0.01 vs 0.35 +/- 0 …
Risk for Major Bleeding in Patients Receiving Ticagrelor Compared With Aspirin After Transient Ischemic Attack or Acute Ischemic Stroke in the SOCRATES Study (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes).
Easton JD, Aunes M, Albers GW, Amarenco P, Bokelund-Singh S, Denison H, Evans SR, Held P, Jahreskog M, Jonasson J, Minematsu K, Molina CA, Wang Y, Wong KSL, Johnston SC; SOCRATES Steering Committee and Investigators. Easton JD, et al. Circulation. 2017 Sep 5;136(10):907-916. doi: 10.1161/CIRCULATIONAHA.117.028566. Epub 2017 Jun 27. Circulation. 2017. PMID: 28655834