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TMEM41B Is a Pan-flavivirus Host Factor.
Hoffmann HH, Schneider WM, Rozen-Gagnon K, Miles LA, Schuster F, Razooky B, Jacobson E, Wu X, Yi S, Rudin CM, MacDonald MR, McMullan LK, Poirier JT, Rice CM. Hoffmann HH, et al. Cell. 2021 Jan 7;184(1):133-148.e20. doi: 10.1016/j.cell.2020.12.005. Epub 2020 Dec 9. Cell. 2021. PMID: 33338421 Free PMC article.
Replication and single-cycle delivery of SARS-CoV-2 replicons.
Ricardo-Lax I, Luna JM, Thao TTN, Le Pen J, Yu Y, Hoffmann HH, Schneider WM, Razooky BS, Fernandez-Martinez J, Schmidt F, Weisblum Y, Trüeb BS, Berenguer Veiga I, Schmied K, Ebert N, Michailidis E, Peace A, Sánchez-Rivera FJ, Lowe SW, Rout MP, Hatziioannou T, Bieniasz PD, Poirier JT, MacDonald MR, Thiel V, Rice CM. Ricardo-Lax I, et al. Among authors: hoffmann hh. Science. 2021 Nov 26;374(6571):1099-1106. doi: 10.1126/science.abj8430. Epub 2021 Oct 14. Science. 2021. PMID: 34648371 Free PMC article.
Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.
Lee D, Le Pen J, Yatim A, Dong B, Aquino Y, Ogishi M, Pescarmona R, Talouarn E, Rinchai D, Zhang P, Perret M, Liu Z, Jordan I, Elmas Bozdemir S, Bayhan GI, Beaufils C, Bizien L, Bisiaux A, Lei W, Hasan M, Chen J, Gaughan C, Asthana A, Libri V, Luna JM, Jaffré F, Hoffmann HH, Michailidis E, Moreews M, Seeleuthner Y, Bilguvar K, Mane S, Flores C, Zhang Y, Arias AA, Bailey R, Schlüter A, Milisavljevic B, Bigio B, Le Voyer T, Materna M, Gervais A, Moncada-Velez M, Pala F, Lazarov T, Levy R, Neehus AL, Rosain J, Peel J, Chan YH, Morin MP, Pino-Ramirez RM, Belkaya S, Lorenzo L, Anton J, Delafontaine S, Toubiana J, Bajolle F, Fumadó V, DeDiego ML, Fidouh N, Rozenberg F, Pérez-Tur J, Chen S, Evans T, Geissmann F, Lebon P, Weiss SR, Bonnet D, Duval X; CoV-Contact Cohort§; COVID Human Genetic Effort¶; Pan-Hammarström Q, Planas AM, Meyts I, Haerynck F, Pujol A, Sancho-Shimizu V, Dalgard CL, Bustamante J, Puel A, Boisson-Dupuis S, Boisson B, Maniatis T, Zhang Q, Bastard P, Notarangelo L, Béziat V, Perez de Diego R, Rodriguez-Gallego C, Su HC, Lifton RP, Jouanguy E, Cobat A, Alsina L, Keles S, Haddad E, Abel L, Belot A, Quintana-Murci L, Rice CM, Silverman RH, Zhang SY, Casanova JL. Lee D, et al. Among authors: hoffmann hh. Science. 2023 Feb 10;379(6632):eabo3627. doi: 10.1126/science.abo3627. Epub 2023 Feb 10. Science. 2023. PMID: 36538032 Free PMC article.
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.
Chung H, Calis JJA, Wu X, Sun T, Yu Y, Sarbanes SL, Dao Thi VL, Shilvock AR, Hoffmann HH, Rosenberg BR, Rice CM. Chung H, et al. Among authors: hoffmann hh. Cell. 2018 Feb 8;172(4):811-824.e14. doi: 10.1016/j.cell.2017.12.038. Epub 2018 Jan 25. Cell. 2018. PMID: 29395325 Free PMC article.
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks.
Schneider WM, Luna JM, Hoffmann HH, Sánchez-Rivera FJ, Leal AA, Ashbrook AW, Le Pen J, Ricardo-Lax I, Michailidis E, Peace A, Stenzel AF, Lowe SW, MacDonald MR, Rice CM, Poirier JT. Schneider WM, et al. Among authors: hoffmann hh. Cell. 2021 Jan 7;184(1):120-132.e14. doi: 10.1016/j.cell.2020.12.006. Epub 2020 Dec 9. Cell. 2021. PMID: 33382968 Free PMC article.
Pan-sarbecovirus prophylaxis with human anti-ACE2 monoclonal antibodies.
Zhang F, Jenkins J, de Carvalho RVH, Nakandakari-Higa S, Chen T, Abernathy ME, Baharani VA, Nyakatura EK, Andrew D, Lebedeva IV, Lorenz IC, Hoffmann HH, Rice CM, Victora GD, Barnes CO, Hatziioannou T, Bieniasz PD. Zhang F, et al. Among authors: hoffmann hh. Nat Microbiol. 2023 Jun;8(6):1051-1063. doi: 10.1038/s41564-023-01389-9. Epub 2023 May 15. Nat Microbiol. 2023. PMID: 37188812 Free PMC article.
Common human genetic variants of APOE impact murine COVID-19 mortality.
Ostendorf BN, Patel MA, Bilanovic J, Hoffmann HH, Carrasco SE, Rice CM, Tavazoie SF. Ostendorf BN, et al. Among authors: hoffmann hh. Nature. 2022 Nov;611(7935):346-351. doi: 10.1038/s41586-022-05344-2. Epub 2022 Sep 21. Nature. 2022. PMID: 36130725 Free PMC article.
TMEM41B is a pan-flavivirus host factor.
Hoffmann HH, Schneider WM, Rozen-Gagnon K, Miles LA, Schuster F, Razooky B, Jacobson E, Wu X, Yi S, Rudin CM, MacDonald MR, McMullan LK, Poirier JT, Rice CM. Hoffmann HH, et al. bioRxiv [Preprint]. 2020 Oct 11:2020.10.09.334128. doi: 10.1101/2020.10.09.334128. bioRxiv. 2020. PMID: 33052348 Free PMC article. Updated. Preprint.
Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection.
Wang Z, Muecksch F, Schaefer-Babajew D, Finkin S, Viant C, Gaebler C, Hoffmann HH, Barnes CO, Cipolla M, Ramos V, Oliveira TY, Cho A, Schmidt F, Da Silva J, Bednarski E, Aguado L, Yee J, Daga M, Turroja M, Millard KG, Jankovic M, Gazumyan A, Zhao Z, Rice CM, Bieniasz PD, Caskey M, Hatziioannou T, Nussenzweig MC. Wang Z, et al. Nature. 2021 Jul;595(7867):426-431. doi: 10.1038/s41586-021-03696-9. Epub 2021 Jun 14. Nature. 2021. PMID: 34126625 Free PMC article.
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes.
Sarbanes SL, Blomen VA, Lam E, Heissel S, Luna JM, Brummelkamp TR, Falck-Pedersen E, Hoffmann HH, Rice CM. Sarbanes SL, et al. Among authors: hoffmann hh. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2015794118. doi: 10.1073/pnas.2015794118. Epub 2020 Dec 21. Proc Natl Acad Sci U S A. 2021. PMID: 33443154 Free PMC article.
18 results