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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1995 1
2001 4
2002 1
2003 1
2004 3
2005 1
2006 2
2007 2
2008 2
2009 2
2010 1
2011 1
2012 1
2014 1
2015 1
2016 5
2017 3
2018 3
2019 2
2020 5
2021 4
2022 7
2023 2
2024 0

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51 results

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Page 1
A pharmacokinetic-pharmacodynamic model for chemoprotective agents against malaria.
Cherkaoui-Rbati MH, Andenmatten N, Burgert L, Egbelowo OF, Fendel R, Fornari C, Gabel M, Ward J, Möhrle JJ, Gobeau N. Cherkaoui-Rbati MH, et al. CPT Pharmacometrics Syst Pharmacol. 2023 Jan;12(1):50-61. doi: 10.1002/psp4.12875. Epub 2022 Nov 22. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36412499 Free PMC article.
A Limited Role for AMD3100 Induced Stem Cell Mobilization for Modulation of Thoracic Trauma Outcome.
Vogel M, Möhrle B, Sakk V, Brown A, Palmer A, Braumüller S, Huber-Lang M, Allgöwer A, Cancelas JA, Geiger H. Vogel M, et al. Shock. 2022 Jun 1;57(6):260-267. doi: 10.1097/SHK.0000000000001933. Shock. 2022. PMID: 35759306
We identified a transient, early increase in the number of inflammatory cells in PB and lung at 2 h post-TXT and a second wave of infiltrating SPCs in lungs by 48 h after TXT induction, suggesting a role for SPCs in tissue remodeling after the initial inflammatory p …
We identified a transient, early increase in the number of inflammatory cells in PB and lung at 2 h post-TXT and a second wave of inf …
Development and application of a PBPK modeling strategy to support antimalarial drug development.
Abla N, Howgate E, Rowland-Yeo K, Dickins M, Bergagnini-Kolev MC, Chen KF, McFeely S, Bonner JJ, Santos LGA, Gobeau N, Burt H, Barter Z, Jones HM, Wesche D, Charman SA, Möhrle JJ, Burrows JN, Almond LM. Abla N, et al. CPT Pharmacometrics Syst Pharmacol. 2023 Sep;12(9):1335-1346. doi: 10.1002/psp4.13013. Epub 2023 Aug 16. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37587640 Free PMC article.
Parasite-Host Dynamics throughout Antimalarial Drug Development Stages Complicate the Translation of Parasite Clearance.
Burgert L, Zaloumis S, Dini S, Marquart L, Cao P, Cherkaoui M, Gobeau N, McCarthy J, Simpson JA, Möhrle JJ, Penny MA. Burgert L, et al. Antimicrob Agents Chemother. 2021 Mar 18;65(4):e01539-20. doi: 10.1128/AAC.01539-20. Print 2021 Mar 18. Antimicrob Agents Chemother. 2021. PMID: 33526486 Free PMC article.
In Plasmodium berghei-NMRI mouse infections, we estimated a maximum parasite clearance rate of 0.2 (1/h); in Plasmodium falciparum-SCID mouse infections, 0.05 (1/h); and in human volunteer infection studies with P. falciparum, we found a maximum parasite clearance r …
In Plasmodium berghei-NMRI mouse infections, we estimated a maximum parasite clearance rate of 0.2 (1/h); in Plasmodium falciparum-SC …
Distinct Dynamics of Stem and Progenitor Cells in Blood of Polytraumatized Patients.
Vogel M, Christow H, Manz I, Denkinger M, Amoah A, Schütz D, Brown A, Möhrle B, Schaffer A, Kalbitz M, Gebhard F, Mayer B, Huber-Lang M, Geiger H. Vogel M, et al. Shock. 2019 Apr;51(4):430-438. doi: 10.1097/SHK.0000000000001198. Shock. 2019. PMID: 30289853 Free PMC article.
We found that the number of blood SPCs follows on average a synchronous, inverse bell-shaped distribution, with an increase at 0 to 3 h, followed by a strong decrease, with a nadir in SPC numbers in blood at 24 or 48 h. The change in numbers of SPCs in PB between 48 …
We found that the number of blood SPCs follows on average a synchronous, inverse bell-shaped distribution, with an increase at 0 to 3 h …
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Coadministered Ruxolitinib and Artemether-Lumefantrine in Healthy Adults.
Chughlay MF, Barnes KI, El Gaaloul M, Abla N, Möhrle JJ, Griffin P, van Giersbergen P, Reuter SE, Schultz HB, Kress A, Tapley P, Webster RA, Wells T, McCarthy JS, Barber BE, Marquart L, Boyle MJ, Engwerda CR, Chalon S. Chughlay MF, et al. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0158421. doi: 10.1128/AAC.01584-21. Epub 2021 Oct 25. Antimicrob Agents Chemother. 2022. PMID: 34694880 Free PMC article. Clinical Trial.
Eight healthy male and female participants ages 18 to 55 years were randomized to either ruxolitinib (20 mg) (n = 6) or placebo (n = 2) administered 2 h after artemether-lumefantrine (80/480 mg) twice daily for 3 days. ...
Eight healthy male and female participants ages 18 to 55 years were randomized to either ruxolitinib (20 mg) (n = 6) or placebo (n = 2) admi …
A Feasibility Study for Immediate Histological Assessment of Various Skin Biopsies Using Ex Vivo Confocal Laser Scanning Microscopy.
Ogrzewalla H, Möhrle M, Metzler G, Eigentler T, Münch AK, Forchhammer S. Ogrzewalla H, et al. Diagnostics (Basel). 2022 Dec 2;12(12):3030. doi: 10.3390/diagnostics12123030. Diagnostics (Basel). 2022. PMID: 36553036 Free PMC article.
BACKGROUND: Digitally stained ex vivo confocal laser scanning microscopy (CLSM) scans are a possible alternative to formalin-fixed and paraffin-embedded (FFPE) and hematoxylin-eosin (H&E) stained slides. This study explores the diagnostic accuracy of digitally-stained …
BACKGROUND: Digitally stained ex vivo confocal laser scanning microscopy (CLSM) scans are a possible alternative to formalin-fixed and paraf …
Cathepsins in basal cell carcinomas: activity, immunoreactivity and mRNA staining of cathepsins B, D, H and L.
Fröhlich E, Möhrle M, Klessen C. Fröhlich E, et al. Arch Dermatol Res. 2004 Mar;295(10):411-21. doi: 10.1007/s00403-003-0449-9. Epub 2004 Feb 7. Arch Dermatol Res. 2004. PMID: 14767779
We determined the activities, immunoreactivities and mRNA of cathepsins B, L and H in sections of different subtypes of BCC. BCC cells and peritumoral cells contained activities for cathepsins B and L. ...The results indicate that cathepsins B and L are involved in invasio …
We determined the activities, immunoreactivities and mRNA of cathepsins B, L and H in sections of different subtypes of BCC. BCC cell …
51 results