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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1966 1
1969 1
1973 1
1974 3
1975 25
1976 43
1977 18
1978 24
1979 30
1980 44
1981 50
1982 57
1983 42
1984 59
1985 55
1986 57
1987 52
1988 62
1989 71
1990 64
1991 62
1992 96
1993 102
1994 107
1995 138
1996 167
1997 169
1998 234
1999 250
2000 338
2001 394
2002 435
2003 505
2004 549
2005 572
2006 510
2007 509
2008 545
2009 550
2010 529
2011 626
2012 670
2013 650
2014 671
2015 678
2016 520
2017 433
2018 620
2019 609
2020 653
2021 657
2022 608
2023 510
2024 106

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13,977 results

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Page 1
Involvement of RhoA/Rho-kinase in l-cysteine/H(2)S pathway-induced inhibition of agonist-mediated corpus cavernosal smooth muscle contraction.
Aydinoglu F, Adıbelli EÖ, Yılmaz-Oral D, Ogulener N. Aydinoglu F, et al. Nitric Oxide. 2019 Apr 1;85:54-60. doi: 10.1016/j.niox.2019.02.001. Epub 2019 Feb 13. Nitric Oxide. 2019. PMID: 30768962
Also, importance of l-cysteine/H(2)S pathway in erectile tissue has been shown; however it is currently unknown the role RhoA/Rho-kinase pathway in H(2)S-induced inhibition in cavernosal tissue. We investigated the role of RhoA/Rho-kinase …
Also, importance of l-cysteine/H(2)S pathway in erectile tissue has been shown; however it is currently unknown the role RhoA/ …
Tensional homeostasis and the malignant phenotype.
Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM. Paszek MJ, et al. Cancer Cell. 2005 Sep;8(3):241-54. doi: 10.1016/j.ccr.2005.08.010. Cancer Cell. 2005. PMID: 16169468 Free article.
Matrix stiffness perturbs epithelial morphogenesis by clustering integrins to enhance ERK activation and increase ROCK-generated contractility and focal adhesions. Contractile, EGF-transformed epithelia with elevated ERK and Rho activity could be phenotypically reverted to …
Matrix stiffness perturbs epithelial morphogenesis by clustering integrins to enhance ERK activation and increase ROCK-generated contractili …
The role of rhoA/rho-kinase and PKC in the inhibitory effect of L-cysteine/H(2)S pathway on the carbachol-mediated contraction of mouse bladder smooth muscle.
Dalkir FT, Aydinoglu F, Ogulener N. Dalkir FT, et al. Naunyn Schmiedebergs Arch Pharmacol. 2023 Sep;396(9):2023-2038. doi: 10.1007/s00210-023-02440-6. Epub 2023 Mar 10. Naunyn Schmiedebergs Arch Pharmacol. 2023. PMID: 36894621
We investigated the role of RhoA/Rho-kinase (ROCK) and PKC in the inhibitory effect of L-cysteine/hydrogen sulfide (H(2)S) pathway on the carbachol-mediated contraction of mouse bladder smooth muscle. Carbachol (10(-8)-10(-4) M) induced a concentration-depend …
We investigated the role of RhoA/Rho-kinase (ROCK) and PKC in the inhibitory effect of L-cysteine/hydrogen sulfide (H(2)S …
H(2)S-mediated inhibition of RhoA/ROCK pathway and noncoding RNAs in ischemic stroke.
Lu W, Wen J. Lu W, et al. Metab Brain Dis. 2023 Jan;38(1):163-176. doi: 10.1007/s11011-022-01130-1. Epub 2022 Dec 5. Metab Brain Dis. 2023. PMID: 36469178 Review.
Accumulating evidences have revealed that hydrogen sulphide (H(2)S) could reduce brain injury in animal model of ischemic stroke via inhibiting the RhoA/ROCK pathway. ...Numerous studies have uncovered the role of RhoA/ROCK pathway and ncRNAs in ischemic stroke. In …
Accumulating evidences have revealed that hydrogen sulphide (H(2)S) could reduce brain injury in animal model of ischemic stro …
The role of arachidonic acid/cyclooxygenase cascade, phosphodiesterase IV and Rho-kinase in H(2)S-induced relaxation in the mouse corpus cavernosum.
Aydinoglu F, Ogulener N. Aydinoglu F, et al. Pharmacol Rep. 2017 Aug;69(4):610-615. doi: 10.1016/j.pharep.2017.02.018. Epub 2017 Feb 24. Pharmacol Rep. 2017. PMID: 28501682
METHODS: The relaxant response to H(2)S (NaHS as exogenous H(2)S; 1-1000muM) were obtained in isolated mouse corpus cavernosum tissues which pre-contracted by phenylephrine (5muM). ...Furthermore, theophylline, rolipram and fasudil reduced H(2) …
METHODS: The relaxant response to H(2)S (NaHS as exogenous H(2)S; 1-1000muM) were obtained in isolated mouse cor …
Association of Fecal and Plasma Levels of Short-Chain Fatty Acids With Gut Microbiota and Clinical Severity in Patients With Parkinson Disease.
Chen SJ, Chen CC, Liao HY, Lin YT, Wu YW, Liou JM, Wu MS, Kuo CH, Lin CH. Chen SJ, et al. Neurology. 2022 Feb 22;98(8):e848-e858. doi: 10.1212/WNL.0000000000013225. Epub 2022 Jan 7. Neurology. 2022. PMID: 34996879 Free PMC article.
After adjustment for age, sex, disease duration, and anti-PD medication dosage, MDS-UPDRS part III motor scores correlated with reduced fecal levels of acetate (rho = -0.37, p = 0.012), propionate (rho = -0.32, p = 0.036), and butyrate (rho = -0.40, p = 0.004 …
After adjustment for age, sex, disease duration, and anti-PD medication dosage, MDS-UPDRS part III motor scores correlated with reduced feca …
Proerectile effects of the Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine (H-1152) in the rat penis.
Teixeira CE, Ying Z, Webb RC. Teixeira CE, et al. J Pharmacol Exp Ther. 2005 Oct;315(1):155-62. doi: 10.1124/jpet.105.086041. Epub 2005 Jun 23. J Pharmacol Exp Ther. 2005. PMID: 15976017
We aimed to investigate the functional effect of a novel Rho-kinase inhibitor, H-1152 [(S)-(+)-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine], both in vitro and in vivo as well as to demonstrate the expression of Rho guanine nucleotide …
We aimed to investigate the functional effect of a novel Rho-kinase inhibitor, H-1152 [(S)-(+)-2-methyl-1-[(4-methyl-5- …
RHO Family GTPases in the Biology of Lymphoma.
Voena C, Chiarle R. Voena C, et al. Cells. 2019 Jun 26;8(7):646. doi: 10.3390/cells8070646. Cells. 2019. PMID: 31248017 Free PMC article. Review.
The RAS family of GTPases that also belong to the RAS GTPase superfamily like the RHO GTPases, includes arguably the most frequently mutated genes in human cancers (K-RAS, N-RAS, and H-RAS) but has been extensively described elsewhere. This review focuses on the rol …
The RAS family of GTPases that also belong to the RAS GTPase superfamily like the RHO GTPases, includes arguably the most frequently …
Rho-dependent termination enables cellular pH homeostasis.
Bhardwaj K, Kalita A, Verma N, Prakash A, Thakur R, Dutta D. Bhardwaj K, et al. J Bacteriol. 2024 Jan 25;206(1):e0035623. doi: 10.1128/jb.00356-23. Epub 2024 Jan 3. J Bacteriol. 2024. PMID: 38169297 Free PMC article.
Since Rho overexpression may increase termination activities, the decrease in cellular pH could result from an excess H(+) ion production during ATP hydrolysis by overproduced Rho. ...Given that the Rho level remained unchanged, the alkaline pH increas …
Since Rho overexpression may increase termination activities, the decrease in cellular pH could result from an excess H(+) ion …
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