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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1990 2
1991 1
1992 2
1993 2
1996 1
1997 2
1998 1
1999 4
2000 2
2001 2
2002 3
2003 2
2004 4
2006 3
2007 3
2008 2
2009 3
2010 2
2011 3
2012 1
2013 2
2014 3
2015 4
2016 2
2017 3
2018 2
2019 2
2020 5
2021 1
2022 4
2023 1
2024 2

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70 results

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Page 1
Features and Outcomes of Histologically Proven Myocarditis With Fulminant Presentation.
Kanaoka K, Onoue K, Terasaki S, Nakano T, Nakai M, Sumita Y, Hatakeyama K, Terasaki F, Kawakami R, Iwanaga Y, Miyamoto Y, Saito Y; Japanese Registry of Fulminant Myocarditis Investigators. Kanaoka K, et al. Circulation. 2022 Nov 8;146(19):1425-1433. doi: 10.1161/CIRCULATIONAHA.121.058869. Epub 2022 Sep 27. Circulation. 2022. PMID: 36164974
Liposomal methemoglobin as a potent antidote for hydrogen sulfide poisoning.
Suzuki Y, Taguchi K, Kure T, Enoki Y, Otagiri M, Sakai H, Matsumoto K. Suzuki Y, et al. Toxicol Appl Pharmacol. 2022 Sep 1;450:116159. doi: 10.1016/j.taap.2022.116159. Epub 2022 Jul 5. Toxicol Appl Pharmacol. 2022. PMID: 35803436
Hydrogen sulfide (H(2)S) induces acute and lethal toxicity at high concentrations. ...As the toxic mechanism of H(2)S poisoning is the same as that of cyanide poisoning, metHb@Lipo could potentially be used as an antidote for H(2)S poisoning. ...
Hydrogen sulfide (H(2)S) induces acute and lethal toxicity at high concentrations. ...As the toxic mechanism of H(2)S poisonin …
Complex formation by the mrpABCDEFG gene products, which constitute a principal Na+/H+ antiporter in Bacillus subtilis.
Kajiyama Y, Otagiri M, Sekiguchi J, Kosono S, Kudo T. Kajiyama Y, et al. J Bacteriol. 2007 Oct;189(20):7511-4. doi: 10.1128/JB.00968-07. Epub 2007 Aug 10. J Bacteriol. 2007. PMID: 17693497 Free PMC article.
The Bacillus subtilis Mrp (also referred to as Sha) is a particularly unusual Na(+)/H(+) antiporter encoded by mrpABCDEFG. Using His tagging of Mrp proteins, we showed complex formation by the mrpABCDEFG gene products by pull-down and blue native polyacrylamide gel electro …
The Bacillus subtilis Mrp (also referred to as Sha) is a particularly unusual Na(+)/H(+) antiporter encoded by mrpABCDEFG. Using His …
In vivo evaluation of drug dialyzability in a rat model of hemodialysis.
Fukunaga M, Kadowaki D, Mori M, Hagiwara S, Narita Y, Saruwatari J, Tanaka R, Watanabe H, Yamasaki K, Taguchi K, Ito H, Maruyama T, Otagiri M, Hirata S. Fukunaga M, et al. PLoS One. 2020 Jun 12;15(6):e0233925. doi: 10.1371/journal.pone.0233925. eCollection 2020. PLoS One. 2020. PMID: 32530952 Free PMC article.
Therefore, the aim of our study is to evaluate drug removal by utilizing a rat model of HD (HD rat) and to extrapolate this result to the drug removal rate in HD patients. HD rats received bilateral nephrectomy and HD for 2 h. The dialysis removal of 6 drugs was evaluated …
Therefore, the aim of our study is to evaluate drug removal by utilizing a rat model of HD (HD rat) and to extrapolate this result to the dr …
Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV.
Higashi-Kuwata N, Hayashi S, Kumamoto H, Ogata-Aoki H, Das D, Venzon D, Hattori SI, Bulut H, Hashimoto M, Otagiri M, Takamune N, Kishimoto N, Davis DA, Misumi S, Kakuni M, Tanaka Y, Mitsuya H. Higashi-Kuwata N, et al. J Hepatol. 2021 May;74(5):1075-1086. doi: 10.1016/j.jhep.2020.12.006. Epub 2020 Dec 15. J Hepatol. 2021. PMID: 33333207 Free PMC article.
Effects of arterial hemorrhage speed on the blood coagulation/fibrinolysis system and hemodynamics in rats.
Furukawa S, Sasao A, Yonemitsu K, Ohtsu Y, Tsutsumi H, Taguchi K, Otagiri M, Nishitani Y. Furukawa S, et al. Blood Coagul Fibrinolysis. 2020 Apr;31(3):198-206. doi: 10.1097/MBC.0000000000000899. Blood Coagul Fibrinolysis. 2020. PMID: 32004201 Clinical Trial.
Male Sprague-Dawley rats (301-396 g) were randomly assigned to five groups depending on hemorrhage speed and length of procedure: first, rapid (1.4 ml/min, 30-min bleeding); second, rapid-L (1.4 ml/min, 30-min bleeding and observation until 6 h); third, slow (0.1 ml/min, i …
Male Sprague-Dawley rats (301-396 g) were randomly assigned to five groups depending on hemorrhage speed and length of procedure: first, rap …
Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity.
Yamasaki K, Iohara D, Oyama Y, Nishizaki N, Kawazu S, Nishi K, Kadowaki D, Taguchi K, Otagiri M, Seo H. Yamasaki K, et al. J Pharm Pharmacol. 2020 Mar;72(3):356-363. doi: 10.1111/jphp.13212. Epub 2019 Dec 11. J Pharm Pharmacol. 2020. PMID: 31828807
Interactions between CDs and these furanocoumarins were also investigated by phase solubility and (1) H NMR studies. KEY FINDINGS: The inhibition of CYP3A by grapefruit juice was significantly attenuated by processing particularly with gammaCD. ...
Interactions between CDs and these furanocoumarins were also investigated by phase solubility and (1) H NMR studies. KEY FINDINGS: Th …
Antioxidant and renoprotective activity of 2-hydroxypropyl-β-cyclodextrin in nephrectomized rats.
Anraku M, Iohara D, Wada K, Taguchi K, Maruyama T, Otagiri M, Uekama K, Hirayama F. Anraku M, et al. J Pharm Pharmacol. 2016 May;68(5):608-14. doi: 10.1111/jphp.12446. Epub 2015 Jun 9. J Pharm Pharmacol. 2016. PMID: 26058311
In in vitro studies, the interaction of HP-beta-CD with a uremic toxin, indole molecule, was much higher than that for the other CDs, as evidenced by Proton nuclear magnetic resonance ((1) H NMR) measurements. CONCLUSIONS: These results suggest that the ingestion of HP-bet …
In in vitro studies, the interaction of HP-beta-CD with a uremic toxin, indole molecule, was much higher than that for the other CDs, as evi …
70 results