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Optical Coherence Tomography-Guided versus Angiography-Guided PCI.
Ali ZA, Landmesser U, Maehara A, Matsumura M, Shlofmitz RA, Guagliumi G, Price MJ, Hill JM, Akasaka T, Prati F, Bezerra HG, Wijns W, Leistner D, Canova P, Alfonso F, Fabbiocchi F, Dogan O, McGreevy RJ, McNutt RW, Nie H, Buccola J, West NEJ, Stone GW; ILUMIEN IV Investigators. Ali ZA, et al. N Engl J Med. 2023 Oct 19;389(16):1466-1476. doi: 10.1056/NEJMoa2305861. Epub 2023 Aug 27. N Engl J Med. 2023. PMID: 37634188 Clinical Trial.
Impact of elevated lipoprotein(a) on coronary artery disease phenotype and severity.
Leistner DM, Laguna-Fernandez A, Haghikia A, Abdelwahed YS, Schatz AS, Erbay A, Roehle R, Fonseca AF, Ferber P, Landmesser U. Leistner DM, et al. Eur J Prev Cardiol. 2024 Feb 13:zwae007. doi: 10.1093/eurjpc/zwae007. Online ahead of print. Eur J Prev Cardiol. 2024. PMID: 38348689

Compared with the normal (Lp(a) < 65 nmol/L) group, elevated Lp(a) groups (e.g. 150 nmol/L) had a higher proportion of patients with prior CAD (48.4% vs. 62.7%; P < 0.01), prior coronary revascularization (39.1% vs. 51.6%; P = 0.01), prior coronary artery bypass graf

…

Compared with the normal (Lp(a) < 65 nmol/L) group, elevated Lp(a) groups (e.g. 150 nmol/L) had a higher proportion of patients wi

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Process development for scale-up production of a therapeutic L-asparaginase by Streptomyces brollosae NEAE-115 from shake flasks to bioreactor.
El-Naggar NE, Moawad H, El-Shweihy NM, El-Ewasy SM, Elsehemy IA, Abdelwahed NAM. El-Naggar NE, et al. Sci Rep. 2019 Sep 19;9(1):13571. doi: 10.1038/s41598-019-49709-6. Sci Rep. 2019. PMID: 31537817 Free PMC article.
As a result, a medium of the following formula is the optimum for producing L-asparaginase in the culture filtrate of Streptomyces brollosae NEAE-115: Dextrose 2 g, starch 20 g, L-asparagine 10 g, KNO(3) 1 g, K(2)HPO(4) 1 g, MgSO(4).7H(2)O 0.5 …
As a result, a medium of the following formula is the optimum for producing L-asparaginase in the culture filtrate of Streptomyces brollosae …
Optimization strategy of Bacillus subtilis MT453867 levansucrase and evaluation of levan role in pancreatic cancer treatment.
Gamal AA, Abbas HY, Abdelwahed NAM, Kashef MT, Mahmoud K, Esawy MA, Ramadan MA. Gamal AA, et al. Int J Biol Macromol. 2021 Jul 1;182:1590-1601. doi: 10.1016/j.ijbiomac.2021.05.056. Epub 2021 May 17. Int J Biol Macromol. 2021. PMID: 34015407
In this work, among eighteen bacterial honey isolates, Bacillus subtilis MT453867 showed the highest levan yield (33 g/L) and levansucrase production (8.31 U/mL). One-factor-at-a-time technique increased levansucrase activity by 60% when MgSO(4) was eliminated. The additio …
In this work, among eighteen bacterial honey isolates, Bacillus subtilis MT453867 showed the highest levan yield (33 g/L) and levansu …
Zika Virus Amplification Using Strand Displacement Isothermal Method and Sequencing Using Nanopore Technology.
Hansen S, Faye O, Sanabani SS, Faye M, Böhlken-Fascher S, Faye O, Sall AA, Bekaert M, Weidmann M, Czerny CP, Abd El Wahed A. Hansen S, et al. Methods Mol Biol. 2020;2142:123-136. doi: 10.1007/978-1-0716-0581-3_11. Methods Mol Biol. 2020. PMID: 32367364
Development of novel point of care diagnostic methods in order to help in implementing disease control program and identifying the causative agent of an outbreak is crucial. Classical diagnostic techniques, e.g., real-time polymerase chain reaction (PCR), rely on the prese …
Development of novel point of care diagnostic methods in order to help in implementing disease control program and identifying the causative …
Suture Coding: A Novel Educational Guide for Suture Patterns.
Gaber M, Abdel-Wahed R. Gaber M, et al. J Surg Educ. 2015 Sep-Oct;72(5):995-1004. doi: 10.1016/j.jsurg.2015.04.016. J Surg Educ. 2015. PMID: 26278657
METHODS: Guide points are fixed on both edges of the wound to act as a guideline to help practice suture pattern techniques. The arrangement is fixed as 1-3-5-7 and a-c-e-g on one side (whether right or left) and as 2-4-6-8 and b-d-f-h on the other side. ...
METHODS: Guide points are fixed on both edges of the wound to act as a guideline to help practice suture pattern techniques. The arrangement …
Chenopodium murale Juice Shows Anti-Fungal Efficacy in Experimental Oral Candidiasis in Immunosuppressed Rats in Relation to Its Chemical Profile.
El-Newary SA, Abd Elkarim AS, Abdelwahed NAM, Omer EA, Elgamal AM, ELsayed WM. El-Newary SA, et al. Molecules. 2023 May 24;28(11):4304. doi: 10.3390/molecules28114304. Molecules. 2023. PMID: 37298777 Free PMC article.
An oral ulcer candidiasis model was created in three stages: (i) immunosuppression by drinking dexamethasone (0.5 mg/L) for two weeks; (ii) Candida albicans infection (3.00 10(6) viable cell/mL) for one week; and (iii) treatment with CMJ (0.5 and 1.0 g/kg orally) or nystat …
An oral ulcer candidiasis model was created in three stages: (i) immunosuppression by drinking dexamethasone (0.5 mg/L) for two weeks; (ii) …
Prognostic Impact of Pancoronary Quantitative Flow Ratio Assessment in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndromes.
Erbay A, Penzel L, Abdelwahed YS, Klotsche J, Heuberger A, Schatz AS, Steiner J, Haghikia A, Sinning D, Fröhlich GM, Landmesser U, Stähli BE, Leistner DM. Erbay A, et al. Circ Cardiovasc Interv. 2021 Dec;14(12):e010698. doi: 10.1161/CIRCINTERVENTIONS.121.010698. Epub 2021 Oct 22. Circ Cardiovasc Interv. 2021. PMID: 34674555
Application of statistical design for the optimization of dextranase production by a novel fungus isolated from Red Sea sponge.
Abdelwahed NA, Ahmed EF, El-Gammal EW, Hawas UW. Abdelwahed NA, et al. 3 Biotech. 2014 Oct;4(5):533-544. doi: 10.1007/s13205-013-0187-4. Epub 2013 Dec 17. 3 Biotech. 2014. PMID: 28324388 Free PMC article.
The model predicted a dextranase activity of 438.15 U/ml when dextran concentration, medium volume and incubation time were 2.1 g/l, 52.47/250 ml flask and 80.48 h, respectively. Verification of the model showed that dextranase production of 440 U/ml was observed un …
The model predicted a dextranase activity of 438.15 U/ml when dextran concentration, medium volume and incubation time were 2.1 g/l, …