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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1985 1
1986 1
1987 1
1988 3
1989 1
1990 3
1991 3
1992 1
1993 2
1994 1
1995 3
1996 3
1997 2
1998 2
1999 1
2000 3
2001 4
2002 2
2003 4
2004 3
2005 11
2006 8
2007 5
2008 6
2009 5
2010 12
2011 7
2012 6
2013 12
2014 11
2015 5
2016 2
2017 3
2018 9
2019 3
2020 1
2023 2
2024 0

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141 results

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Page 1
Nonlinear Protein Binding: Not What You Think.
Deitchman AN, Singh RSP, Derendorf H. Deitchman AN, et al. J Pharm Sci. 2018 Jul;107(7):1754-1760. doi: 10.1016/j.xphs.2018.03.023. Epub 2018 Apr 4. J Pharm Sci. 2018. PMID: 29626534 Free PMC article. Review.
Pharmacokinetic/pharmacodynamic profile of posaconazole.
Li Y, Theuretzbacher U, Clancy CJ, Nguyen MH, Derendorf H. Li Y, et al. Clin Pharmacokinet. 2010 Jun;49(6):379-96. doi: 10.2165/11319340-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20481649 Review.
Posaconazole has a median terminal elimination half-life of 15-35 hours. The renal elimination of posaconazole is less than 1 mL/h, which is negligible compared with the mean total oral clearance of 16.3 L/h. ...
Posaconazole has a median terminal elimination half-life of 15-35 hours. The renal elimination of posaconazole is less than 1 mL/h, w …
Clinical Pharmacokinetics and Pharmacodynamics of Ceftazidime-Avibactam Combination: A Model-Informed Strategy for its Clinical Development.
Sy SKB, Zhuang L, Sy S, Derendorf H. Sy SKB, et al. Clin Pharmacokinet. 2019 May;58(5):545-564. doi: 10.1007/s40262-018-0705-y. Clin Pharmacokinet. 2019. PMID: 30097887 Review.
Ceftazidime and avibactam have complementary pharmacokinetic (PK) profiles. Both drugs have a half-life of approximately 2 h, making them suitable to be combined in a fixed-dose combination ratio of 4:1 (ceftazidime:avibactam). ...The clinical dosing regimen of 2/0.5 g cef …
Ceftazidime and avibactam have complementary pharmacokinetic (PK) profiles. Both drugs have a half-life of approximately 2 h, making …
Pharmacokinetics and bioavailability of the flavonol quercetin in humans.
Graefe EU, Derendorf H, Veit M. Graefe EU, et al. Int J Clin Pharmacol Ther. 1999 May;37(5):219-33. Int J Clin Pharmacol Ther. 1999. PMID: 10363620 Review.
The pharmacokinetic parameters following intravenous injection were determined in two studies. The elimination half-life was reported to be 2.4 h and 0.7 h, the volume of distribution at steady-state was 92.6 l and 6.2 l, and total body clearance was 34.6 lxh(-1) an …
The pharmacokinetic parameters following intravenous injection were determined in two studies. The elimination half-life was reported to be …
Class-dependent relevance of tissue distribution in the interpretation of anti-infective pharmacokinetic/pharmacodynamic indices.
Barbour A, Scaglione F, Derendorf H. Barbour A, et al. Int J Antimicrob Agents. 2010 May;35(5):431-8. doi: 10.1016/j.ijantimicag.2010.01.023. Int J Antimicrob Agents. 2010. PMID: 20219329 Review.
The most common indices include the time free drug concentration in plasma is above the minimum inhibitory concentration (MIC) (fT(>MIC)) expressed as a percent of the dosing interval, the ratio of maximum concentration to MIC (C(max)/MIC), and the ratio of the area under the …
The most common indices include the time free drug concentration in plasma is above the minimum inhibitory concentration (MIC) (fT(>MIC)) …
141 results