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Synthesis and biological evaluation of xanthine derivatives with phenacyl group as tryptophan hydroxylase 1 (TPH1) inhibitors for obesity and fatty liver disease.
Yoon J, Choi WI, Parameswaran S, Lee GB, Choi BW, Kim P, Shin DS, Jeong HN, Lee SM, Oh CJ, Jeon JH, Lee IK, Bae MA, Kim H, Ahn JH. Yoon J, et al. Among authors: lee gb. Bioorg Med Chem Lett. 2023 Oct 1;94:129461. doi: 10.1016/j.bmcl.2023.129461. Epub 2023 Aug 29. Bioorg Med Chem Lett. 2023. PMID: 37652099
Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes.
Pagire SH, Pagire HS, Lee GB, Han SJ, Kwak HJ, Kim JY, Kim KY, Rhee SD, Ryu JI, Song JS, Bae MA, Park MJ, Kim D, Lee DH, Ahn JH. Pagire SH, et al. Among authors: lee gb. Eur J Med Chem. 2015 Aug 28;101:716-35. doi: 10.1016/j.ejmech.2015.06.043. Epub 2015 Jun 27. Eur J Med Chem. 2015. PMID: 26218650