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Year Number of Results
2013 1
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2015 1
2017 3
2018 1
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2020 3
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Page 1
Rational-Based Discovery of Novel β-Carboline Derivatives as Potential Antimalarials: From In Silico Identification of Novel Targets to Inhibition of Experimental Cerebral Malaria.
Alves FM, Bellei JCB, Barbosa CS, Duarte CL, Fonseca ALD, Pinto ACS, Raimundo FO, Carpinter BA, Lemos ASO, Coimbra ES, Taranto AG, Rocha VN, de Pilla Varotti F, Ribeiro Viana GH, Scopel KKG. Alves FM, et al. Among authors: ribeiro viana gh. Pathogens. 2022 Dec 13;11(12):1529. doi: 10.3390/pathogens11121529. Pathogens. 2022. PMID: 36558863 Free PMC article.
Metabolic activation enhances the cytotoxicity, genotoxicity and mutagenicity of two synthetic alkaloids with selective effects against human tumour cell lines.
Oliveira JT, Franco FN, Tecchio KB, Gonçalves AMMN, Barbosa CS, Ribeiro RIMA, Viana GHR, Santos VJDSVD, Santos FVD. Oliveira JT, et al. Among authors: viana ghr. Mutat Res Genet Toxicol Environ Mutagen. 2021 Jan-Feb;861-862:503294. doi: 10.1016/j.mrgentox.2020.503294. Epub 2020 Nov 7. Mutat Res Genet Toxicol Environ Mutagen. 2021. PMID: 33551097 Free article.
Design, synthesis, and biodistribution studies of new analogues of marine alkaloids: Potent in vitro and in vivo fungicidal agents against Candida spp.
Andrade JT, Lima WG, Sousa JF, Saldanha AA, Nívea Pereira De Sá, Morais FB, Prates Silva MK, Ribeiro Viana GH, Johann S, Soares AC, Araújo LA, Antunes Fernandes SO, Cardoso VN, Siqueira Ferreira JM. Andrade JT, et al. Among authors: ribeiro viana gh. Eur J Med Chem. 2021 Jan 15;210:113048. doi: 10.1016/j.ejmech.2020.113048. Epub 2020 Dec 3. Eur J Med Chem. 2021. PMID: 33316690
Improvement of antimalarial activity of a 3-alkylpiridine alkaloid analog by replacing the pyridine ring to a thiazole-containing heterocycle: Mode of action, mutagenicity profile, and Caco-2 cell-based permeability.
Guimarães DSM, de Sousa Luz LS, do Nascimento SB, Silva LR, de Miranda Martins NR, de Almeida HG, de Souza Reis V, Maluf SEC, Budu A, Marinho JA, Abramo C, Carmona AK, da Silva MG, da Silva GR, Kemmer VM, Butera AP, Ribeiro-Viana RM, Gazarini ML, Júnior CSN, Guimarães L, Dos Santos FV, de Castro WV, Viana GHR, de Brito CFA, de Pilla Varotti F. Guimarães DSM, et al. Among authors: viana ghr. Eur J Pharm Sci. 2019 Oct 1;138:105015. doi: 10.1016/j.ejps.2019.105015. Epub 2019 Jul 22. Eur J Pharm Sci. 2019. PMID: 31344442
Nanoemulsion composed of 10-(4,5-dihydrothiazol-2-yl)thio)decan-1-ol), a synthetic analog of 3-alkylpiridine marine alkaloid: development, characterization, and antimalarial activity.
Silva MGD, Cardoso JF, Perasoli FB, Branquinho RT, Mourão RS, Tavares HDS, Xocaira MLCT, Guimarães DSM, Viana GHR, Varotti FP, Silva GRD. Silva MGD, et al. Among authors: viana ghr. Eur J Pharm Sci. 2020 Aug 1;151:105382. doi: 10.1016/j.ejps.2020.105382. Epub 2020 May 26. Eur J Pharm Sci. 2020. PMID: 32470575
Synthesis and evaluation of the mutagenicity of 3-alkylpyridine marine alkaloid analogues with anticancer potential.
Barbosa MCS, de Souza Barbosa C, de Oliveira JT, Moreira NCS, de Miranda Martins NR, Alves Gomes GK, Caldeira CA, Alves E Costa ML, Martins Guimarães DS, Guimarães L, Nascimento CS Jr, de Pilla Varotti F, Ribeiro Viana GH, Santos FVD. Barbosa MCS, et al. Among authors: ribeiro viana gh. Mutat Res Genet Toxicol Environ Mutagen. 2018 Jan;825:31-39. doi: 10.1016/j.mrgentox.2017.11.006. Epub 2017 Nov 24. Mutat Res Genet Toxicol Environ Mutagen. 2018. PMID: 29307373
New quinoline derivatives demonstrate a promising antimalarial activity against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.
Soares RR, da Silva JM, Carlos BC, da Fonseca CC, de Souza LS, Lopes FV, de Paula Dias RM, Moreira PO, Abramo C, Viana GH, de Pila Varotti F, da Silva AD, Scopel KK. Soares RR, et al. Among authors: viana gh. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2308-13. doi: 10.1016/j.bmcl.2015.04.014. Epub 2015 Apr 11. Bioorg Med Chem Lett. 2015. PMID: 25920564
Antimalarial activity of 4-metoxychalcones: docking studies as falcipain/plasmepsin inhibitors, ADMET and lipophilic efficiency analysis to identify a putative oral lead candidate.
de Oliveira ME, Cenzi G, Nunes RR, Andrighetti CR, de Sousa Valadão DM, Dos Reis C, Simões CM, Nunes RJ, Júnior MC, Taranto AG, Sanchez BA, Viana GH, de Pilla Varotti F. de Oliveira ME, et al. Among authors: viana gh. Molecules. 2013 Dec 10;18(12):15276-87. doi: 10.3390/molecules181215276. Molecules. 2013. PMID: 24335577 Free PMC article.
Target-Guided Synthesis and Antiplasmodial Evaluation of a New Fluorinated 3-Alkylpyridine Marine Alkaloid Analog.
Barbosa CS, Guimarães DSM, Gonçalves AMMN, Barbosa MCDS, Alves E Costa ML, Nascimento Júnior CS, Guimarães L, Ribeiro-Viana RM, Dos Santos FV, Alves de Brito CF, de Pilla Varotti F, Ribeiro Viana GH. Barbosa CS, et al. Among authors: ribeiro viana gh. ACS Omega. 2017 Nov 30;2(11):8264-8272. doi: 10.1021/acsomega.7b01302. Epub 2017 Nov 21. ACS Omega. 2017. PMID: 30023579 Free PMC article.
11 results