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Sézary syndrome originates from heavily mutated hematopoietic progenitors.
Harro CM, Sprenger KB, Chaurio RA, Powers JJ, Innamarato P, Anadon CM, Zhang Y, Biswas S, Mandal G, Mine JA, Cortina C, Nagy MZ, Martin AL, Handley KF, Borjas GJ, Chen PL, Pinilla-Ibarz J, Sokol L, Yu X, Conejo-Garcia JR. Harro CM, et al. Among authors: borjas gj. Blood Adv. 2023 Sep 26;7(18):5586-5602. doi: 10.1182/bloodadvances.2022008562. Blood Adv. 2023. PMID: 37531660 Free PMC article.
A Phase II Study of Durvalumab for Bacillus Calmette-Guerin (BCG) Unresponsive Urothelial Carcinoma In Situ of the Bladder.
Li R, Sexton WJ, Dhillon J, Berglund A, Naidu S, Borjas G, Rose K, Kim Y, Wang X, Conejo-Garcia JR, Jain RK, Poch MA, Spiess PE, Pow-Sang J, Gilbert SM, Zhang J. Li R, et al. Among authors: borjas g. Clin Cancer Res. 2023 Oct 2;29(19):3875-3881. doi: 10.1158/1078-0432.CCR-23-0354. Clin Cancer Res. 2023. PMID: 37505486 Clinical Trial.
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity.
Kang S, Mansurov A, Kurtanich T, Chun HR, Slezak AJ, Volpatti LR, Chang K, Wang T, Alpar AT, Refvik KC, Hansen OI, Borjas GJ, Shim HN, Hultgren KT, Gomes S, Solanki A, Ishihara J, Swartz MA, Hubbell JA. Kang S, et al. Among authors: borjas gj. Sci Adv. 2023 Dec;9(48):eadh9879. doi: 10.1126/sciadv.adh9879. Epub 2023 Nov 29. Sci Adv. 2023. PMID: 38019919 Free PMC article.
LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice.
Volpatti LR, de Matos SN, Borjas G, Reda J, Watkins EA, Zhou Z, Nguyen M, Solanki A, Fang Y, Hubbell JA. Volpatti LR, et al. Among authors: borjas g. bioRxiv [Preprint]. 2024 Mar 6:2024.03.04.582839. doi: 10.1101/2024.03.04.582839. bioRxiv. 2024. PMID: 38496521 Free PMC article. Preprint.