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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
2004 2
2005 3
2006 5
2008 1
2009 1
2010 2
2011 2
2013 2
2014 2
2015 8
2016 11
2017 8
2018 8
2019 11
2020 20
2021 16
2022 10
2023 23
2024 12

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121 results

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Page 1
Tendon basic science: Development, repair, regeneration, and healing.
Andarawis-Puri N, Flatow EL, Soslowsky LJ. Andarawis-Puri N, et al. J Orthop Res. 2015 Jun;33(6):780-4. doi: 10.1002/jor.22869. Epub 2015 Apr 24. J Orthop Res. 2015. PMID: 25764524 Free PMC article. Review.
Despite the prevalence of these injuries, a limited number of investigators are conducting fundamental, basic science studies focused on understanding processes governing tendinopathies and tendon healing. Development of effective therapeutics is hindered by the lack of fu …
Despite the prevalence of these injuries, a limited number of investigators are conducting fundamental, basic science studies focused on und …
Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma.
Calsina B, Piñeiro-Yáñez E, Martínez-Montes ÁM, Caleiras E, Fernández-Sanromán Á, Monteagudo M, Torres-Pérez R, Fustero-Torre C, Pulgarín-Alfaro M, Gil E, Letón R, Jiménez S, García-Martín S, Martin MC, Roldán-Romero JM, Lanillos J, Mellid S, Santos M, Díaz-Talavera A, Rubio Á, González P, Hernando B, Bechmann N, Dona M, Calatayud M, Guadalix S, Álvarez-Escolá C, Regojo RM, Aller J, Del Olmo-Garcia MI, López-Fernández A, Fliedner SMJ, Rapizzi E, Fassnacht M, Beuschlein F, Quinkler M, Toledo RA, Mannelli M, Timmers HJ, Eisenhofer G, Rodríguez-Perales S, Domínguez O, Macintyre G, Currás-Freixes M, Rodríguez-Antona C, Cascón A, Leandro-García LJ, Montero-Conde C, Roncador G, García-García JF, Pacak K, Al-Shahrour F, Robledo M. Calsina B, et al. Nat Commun. 2023 Feb 28;14(1):1122. doi: 10.1038/s41467-023-36769-6. Nat Commun. 2023. PMID: 36854674 Free PMC article.
The mechanisms triggering metastasis in pheochromocytoma/paraganglioma are unknown, hindering therapeutic options for patients with metastatic tumors (mPPGL). ...
The mechanisms triggering metastasis in pheochromocytoma/paraganglioma are unknown, hindering therapeutic options for patients with m …
Rapid recruitment and IFN-I-mediated activation of monocytes dictate focal radiotherapy efficacy.
Tadepalli S, Clements DR, Saravanan S, Arroyo Hornero R, Lüdtke A, Blackmore B, Paulo JA, Gottfried-Blackmore A, Seong D, Park S, Chan L, Kopecky BJ, Liu Z, Ginhoux F, Lavine KJ, Murphy JP, Mack M, Graves EE, Idoyaga J. Tadepalli S, et al. Sci Immunol. 2023 Jun 2;8(84):eadd7446. doi: 10.1126/sciimmunol.add7446. Epub 2023 Jun 9. Sci Immunol. 2023. PMID: 37294749
We also demonstrate that monocyte accumulation in the tumor microenvironment is hindered when RT inadvertently affects healthy tissues, as occurs in non-CRT. ...
We also demonstrate that monocyte accumulation in the tumor microenvironment is hindered when RT inadvertently affects healthy tissue …
Candidemia in the Intensive Care Unit.
Epelbaum O, Chasan R. Epelbaum O, et al. Clin Chest Med. 2017 Sep;38(3):493-509. doi: 10.1016/j.ccm.2017.04.010. Epub 2017 Jun 16. Clin Chest Med. 2017. PMID: 28797491 Review.
The absence of well-established molecular techniques for early detection of candidemia hinders efforts to reduce the heavy clinical and economic impact of this infection. ...
The absence of well-established molecular techniques for early detection of candidemia hinders efforts to reduce the heavy clinical a …
Targeting immunogenic cell stress and death for cancer therapy.
Galluzzi L, Guilbaud E, Schmidt D, Kroemer G, Marincola FM. Galluzzi L, et al. Nat Rev Drug Discov. 2024 Apr 15. doi: 10.1038/s41573-024-00920-9. Online ahead of print. Nat Rev Drug Discov. 2024. PMID: 38622310 Review.
Several therapeutic strategies to elicit ICD - either as standalone approaches or as means to convert immunologically cold tumours that are insensitive to immunotherapy into hot and immunotherapy-sensitive lesions - are being actively pursued. However, the development of ICD-indu …
Several therapeutic strategies to elicit ICD - either as standalone approaches or as means to convert immunologically cold tumours that are …
Caries Management-The Role of Surface Interactions in De- and Remineralization-Processes.
Flemming J, Hannig C, Hannig M. Flemming J, et al. J Clin Med. 2022 Nov 28;11(23):7044. doi: 10.3390/jcm11237044. J Clin Med. 2022. PMID: 36498618 Free PMC article. Review.
Proteinaceous layers on dental hard tissues can prevent or aggravate demineralization processes, whereas proteins within initial erosive or carious lesions might hinder remineralization considerably and restrict the entry of ions into lesions. ...
Proteinaceous layers on dental hard tissues can prevent or aggravate demineralization processes, whereas proteins within initial erosive or …
Dystrophin myonuclear domain restoration governs treatment efficacy in dystrophic muscle.
Morin A, Stantzou A, Petrova ON, Hildyard J, Tensorer T, Matouk M, Petkova MV, Richard I, Manoliu T, Goyenvalle A, Falcone S, Schuelke M, Laplace-Builhé C, Piercy RJ, Garcia L, Amthor H. Morin A, et al. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2206324120. doi: 10.1073/pnas.2206324120. Epub 2023 Jan 3. Proc Natl Acad Sci U S A. 2023. PMID: 36595689 Free PMC article.
However, its normal, spatial organization remains poorly understood, which hinders the interpretation of efficacy of its therapeutic restoration. ...
However, its normal, spatial organization remains poorly understood, which hinders the interpretation of efficacy of its therapeutic …
Defective proteostasis in celiac disease as a new therapeutic target.
Maiuri L, Villella VR, Piacentini M, Raia V, Kroemer G. Maiuri L, et al. Cell Death Dis. 2019 Feb 8;10(2):114. doi: 10.1038/s41419-019-1392-9. Cell Death Dis. 2019. PMID: 30737369 Free PMC article. Review.
These three phenomena (CFTR inhibition, TGM2 activation, and autophagy impairment) engage in multiple self-amplifying circuitries, thus forming an "infernal trio". The trio hinders enterocytes from returning to homeostasis and instead locks them in an irreversible pro-infl …
These three phenomena (CFTR inhibition, TGM2 activation, and autophagy impairment) engage in multiple self-amplifying circuitries, thus form …
Clinical predictors of COVID-19 mortality.
Yadaw AS, Li YC, Bose S, Iyengar R, Bunyavanich S, Pandey G. Yadaw AS, et al. medRxiv [Preprint]. 2020 May 22:2020.05.19.20103036. doi: 10.1101/2020.05.19.20103036. medRxiv. 2020. PMID: 32511520 Free PMC article. Updated. Preprint.
It can be difficult to accurately predict mortality among COVID-19 patients presenting with a spectrum of complications, hindering the prognostication and management of the disease. METHODS: We applied machine learning techniques to clinical data from a large cohort of 5,0 …
It can be difficult to accurately predict mortality among COVID-19 patients presenting with a spectrum of complications, hindering th …
Precision medicine for metastatic breast cancer--limitations and solutions.
Arnedos M, Vicier C, Loi S, Lefebvre C, Michiels S, Bonnefoi H, Andre F. Arnedos M, et al. Nat Rev Clin Oncol. 2015 Dec;12(12):693-704. doi: 10.1038/nrclinonc.2015.123. Epub 2015 Jul 21. Nat Rev Clin Oncol. 2015. PMID: 26196250 Review.
The development of precision medicine for the management of metastatic breast cancer is an appealing concept; however, major scientific and logistical challenges hinder its implementation in the clinic. The identification of driver mutational events remains the biggest cha …
The development of precision medicine for the management of metastatic breast cancer is an appealing concept; however, major scientific and …
121 results