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Catalpolaglycone disrupts mitochondrial thermogenesis by specifically binding to a conserved lysine residue of UCP2 on the proton leak tunnel.
Phytomedicine. 2024 Mar;125:155356. doi: 10.1016/j.phymed.2024.155356. Epub 2024 Jan 14.
Phytomedicine. 2024.
PMID: 38241920
Ligustilide covalently binds to Cys703 in the pre-S1 helix of TRPA1, blocking the opening of channel and relieving pain in rats with acute soft tissue injury.
Zhang K, Liu W, Shen F, Luan G, Han Y, Xu J, Fu C, Wu W, Hou Y, Jiang M, Zhang T, Bai G.
Zhang K, et al. Among authors: luan g.
J Ethnopharmacol. 2024 Apr 17:118217. doi: 10.1016/j.jep.2024.118217. Online ahead of print.
J Ethnopharmacol. 2024.
PMID: 38641072
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