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Page 1
Showing results for guiding zhou
Search for Guixing Zhou instead (1 results)
Spatial transcriptomics.
Anderson AC, Yanai I, Yates LR, Wang L, Swarbrick A, Sorger P, Santagata S, Fridman WH, Gao Q, Jerby L, Izar B, Shang L, Zhou X. Anderson AC, et al. Cancer Cell. 2022 Sep 12;40(9):895-900. doi: 10.1016/j.ccell.2022.08.021. Cancer Cell. 2022. PMID: 36099884 Free article.
We asked experts to discuss some aspects of this technology from revealing the tumor microenvironment and heterogeneity, to tracking tumor evolution, to guiding tumor therapy, to current technical challenges....
We asked experts to discuss some aspects of this technology from revealing the tumor microenvironment and heterogeneity, to tracking tumor e …
Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex.
Kato K, Zhou W, Okazaki S, Isayama Y, Nishizawa T, Gootenberg JS, Abudayyeh OO, Nishimasu H. Kato K, et al. Cell. 2022 Jun 23;185(13):2324-2337.e16. doi: 10.1016/j.cell.2022.05.003. Epub 2022 May 27. Cell. 2022. PMID: 35643083 Free article.
The type III-E CRISPR-Cas effector Cas7-11, with dual RNase activities for precursor CRISPR RNA (pre-crRNA) processing and crRNA-guided target RNA cleavage, is a new platform for bacterial and mammalian RNA targeting. ...
The type III-E CRISPR-Cas effector Cas7-11, with dual RNase activities for precursor CRISPR RNA (pre-crRNA) processing and crRNA-guided …
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA. Jinek M, et al. Science. 2014 Mar 14;343(6176):1247997. doi: 10.1126/science.1247997. Epub 2014 Feb 6. Science. 2014. PMID: 24505130 Free PMC article.
Type II CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems use an RNA-guided DNA endonuclease, Cas9, to generate double-strand breaks in invasive DNA during an adaptive bacterial immune response. ...The observation that exten …
Type II CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems use an RNA-guided DNA endo …
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
Jiang F, Taylor DW, Chen JS, Kornfeld JE, Zhou K, Thompson AJ, Nogales E, Doudna JA. Jiang F, et al. Science. 2016 Feb 19;351(6275):867-71. doi: 10.1126/science.aad8282. Epub 2016 Jan 14. Science. 2016. PMID: 26841432 Free PMC article.
Bacterial adaptive immunity and genome engineering involving the CRISPR (clustered regularly interspaced short palindromic repeats)-associated (Cas) protein Cas9 begin with RNA-guided DNA unwinding to form an RNA-DNA hybrid and a displaced DNA strand inside the protein. .. …
Bacterial adaptive immunity and genome engineering involving the CRISPR (clustered regularly interspaced short palindromic repeats)-associat …
Good-enough attentional guidance.
Yu X, Zhou Z, Becker SI, Boettcher SEP, Geng JJ. Yu X, et al. Trends Cogn Sci. 2023 Apr;27(4):391-403. doi: 10.1016/j.tics.2023.01.007. Epub 2023 Feb 24. Trends Cogn Sci. 2023. PMID: 36841692 Free article. Review.
The template is often thought to contain veridical target features, akin to a photograph, and to guide attention to objects that match the exact target features. However, recent evidence suggests that attentional guidance is highly flexible and often guided by non-v …
The template is often thought to contain veridical target features, akin to a photograph, and to guide attention to objects that matc …
Invariant inhibition to calculate prediction errors?
Creed MC, Loureiro M, Lüscher C. Creed MC, et al. Trends Neurosci. 2023 Apr;46(4):257-259. doi: 10.1016/j.tins.2023.01.004. Epub 2023 Jan 26. Trends Neurosci. 2023. PMID: 36707259
Much of the research on the VTA has focused on the mesocorticolimbic dopamine projections and their role in the computation of a 'reward prediction error' (RPE) for reward-guided learning. In a recent study, Zhou et al. report that VTA GABA neurons, the axons of whi …
Much of the research on the VTA has focused on the mesocorticolimbic dopamine projections and their role in the computation of a 'reward pre …
Current perioperative management of cerebrospinal fluid drains.
Zhou SF, Tanaka A, Estrera A. Zhou SF, et al. Ann Cardiothorac Surg. 2023 Sep 28;12(5):487-488. doi: 10.21037/acs-2023-scp-19. Epub 2023 Jul 24. Ann Cardiothorac Surg. 2023. PMID: 37817845 Free PMC article. No abstract available.
Renal Tumor Biopsy Technique.
Zhang L, Li XS, Zhou LQ. Zhang L, et al. Chin Med J (Engl). 2016 May 20;129(10):1236-40. doi: 10.4103/0366-6999.181957. Chin Med J (Engl). 2016. PMID: 27174334 Free PMC article. Review.
RESULTS: Computed tomography and ultrasound were usually used for guiding RTB with respective advantages. Core biopsy is more preferred over fine needle aspiration because of superior accuracy. A minimum of two good-quality cores for a single renal tumor is generally accep …
RESULTS: Computed tomography and ultrasound were usually used for guiding RTB with respective advantages. Core biopsy is more preferr …
Hypoxia-activated nanomedicines for effective cancer therapy.
Zhou M, Xie Y, Xu S, Xin J, Wang J, Han T, Ting R, Zhang J, An F. Zhou M, et al. Eur J Med Chem. 2020 Jun 1;195:112274. doi: 10.1016/j.ejmech.2020.112274. Epub 2020 Mar 30. Eur J Med Chem. 2020. PMID: 32259703 Review.
These approaches include: i) inhibitors of hypoxia-associated signaling pathways; ii) prodrugs activated by hypoxia; iii) nanocarriers responsive to hypoxia, and iv) bacteria mediated hypoxia targeting therapy. These strategies have guided and will continue to guide …
These approaches include: i) inhibitors of hypoxia-associated signaling pathways; ii) prodrugs activated by hypoxia; iii) nanocarriers respo …
Expert consensus on digital guided therapy for endodontic diseases.
Wei X, Du Y, Zhou X, Yue L, Yu Q, Hou B, Chen Z, Liang J, Chen W, Qiu L, Huang X, Meng L, Huang D, Wang X, Tian Y, Tang Z, Zhang Q, Miao L, Zhao J, Yang D, Yang J, Ling J. Wei X, et al. Int J Oral Sci. 2023 Dec 6;15(1):54. doi: 10.1038/s41368-023-00261-0. Int J Oral Sci. 2023. PMID: 38052782 Free PMC article. Review.
Digital guided therapy (DGT) has been advocated as a contemporary computer-aided technique for treating endodontic diseases in recent decades. The concept of DGT for endodontic diseases is categorized into static guided endodontics (SGE), necessitating a meticulousl …
Digital guided therapy (DGT) has been advocated as a contemporary computer-aided technique for treating endodontic diseases in recent …
9,732 results