Guangchuan Wang - Search Results

Year	Number of Results
2009	1
2010	2
2011	1
2012	2
2013	5
2014	10
2015	12
2016	7
2017	6
2018	6
2019	17
2020	11
2021	8
2022	9
2023	15
2024	5

1

Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity.

Yan C, Zheng L, Jiang S, Yang H, Guo J, Jiang LY, Li T, Zhang H, Bai Y, Lou Y, Zhang Q, Liang T, Schamel W, Wang H, Yang W, Wang G, Zhu ZJ, Song BL, Xu C. Yan C, et al. Among authors: wang g. Cancer Cell. 2023 Jul 10;41(7):1276-1293.e11. doi: 10.1016/j.ccell.2023.04.016. Epub 2023 May 26. Cancer Cell. 2023. PMID: 37244259

2

A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy.

Ye L, Park JJ, Peng L, Yang Q, Chow RD, Dong MB, Lam SZ, Guo J, Tang E, Zhang Y, Wang G, Dai X, Du Y, Kim HR, Cao H, Errami Y, Clark P, Bersenev A, Montgomery RR, Chen S. Ye L, et al. Among authors: wang g. Cell Metab. 2022 Apr 5;34(4):595-614.e14. doi: 10.1016/j.cmet.2022.02.009. Epub 2022 Mar 10. Cell Metab. 2022. PMID: 35276062 Free PMC article.

3

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells.

Dong MB, Wang G, Chow RD, Ye L, Zhu L, Dai X, Park JJ, Kim HR, Errami Y, Guzman CD, Zhou X, Chen KY, Renauer PA, Du Y, Shen J, Lam SZ, Zhou JJ, Lannin DR, Herbst RS, Chen S. Dong MB, et al. Among authors: wang g. Cell. 2019 Aug 22;178(5):1189-1204.e23. doi: 10.1016/j.cell.2019.07.044. Cell. 2019. PMID: 31442407 Free PMC article.

4

CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade.

Wang G, Chow RD, Zhu L, Bai Z, Ye L, Zhang F, Renauer PA, Dong MB, Dai X, Zhang X, Du Y, Cheng Y, Niu L, Chu Z, Kim K, Liao C, Clark P, Errami Y, Chen S. Wang G, et al. Cancer Discov. 2020 Dec;10(12):1912-1933. doi: 10.1158/2159-8290.CD-19-1448. Epub 2020 Sep 4. Cancer Discov. 2020. PMID: 32887696 Free PMC article.

5

Immunogenetic Metabolomics Reveals Key Enzymes That Modulate CAR T-cell Metabolism and Function.

Renauer P, Park JJ, Bai M, Acosta A, Lee WH, Lin GH, Zhang Y, Dai X, Wang G, Errami Y, Wu T, Clark P, Ye L, Yang Q, Chen S. Renauer P, et al. Among authors: wang g. Cancer Immunol Res. 2023 Aug 3;11(8):1068-1084. doi: 10.1158/2326-6066.CIR-22-0565. Cancer Immunol Res. 2023. PMID: 37253111 Free PMC article.

6

In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma.

Ye L, Park JJ, Dong MB, Yang Q, Chow RD, Peng L, Du Y, Guo J, Dai X, Wang G, Errami Y, Chen S. Ye L, et al. Among authors: wang g. Nat Biotechnol. 2019 Nov;37(11):1302-1313. doi: 10.1038/s41587-019-0246-4. Epub 2019 Sep 23. Nat Biotechnol. 2019. PMID: 31548728 Free PMC article.

7

Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells.

Meng D, Li Z, Wang G, Ling L, Wu Y, Zhang C. Meng D, et al. Among authors: wang g. Biomed Pharmacother. 2018 Dec;108:1617-1627. doi: 10.1016/j.biopha.2018.10.005. Epub 2018 Oct 10. Biomed Pharmacother. 2018. PMID: 30372864 Free article.

8

Gasdermin D-mediated pyroptosis is regulated by AMPK-mediated phosphorylation in tumor cells.

Chu X, Xiao X, Wang G, Uosef A, Lou X, Arnold P, Wang Y, Kong G, Wen M, Minze LJ, Li XC. Chu X, et al. Among authors: wang g. Cell Death Dis. 2023 Jul 26;14(7):469. doi: 10.1038/s41419-023-06013-6. Cell Death Dis. 2023. PMID: 37495617 Free PMC article.

9

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.

Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, Renauer P, Bilguvar K, Gunel M, Sharp PA, Zhang F, Platt RJ, Chen S. Chow RD, et al. Among authors: wang g. Nat Neurosci. 2017 Oct;20(10):1329-1341. doi: 10.1038/nn.4620. Epub 2017 Aug 14. Nat Neurosci. 2017. PMID: 28805815 Free PMC article.

10

Deep Convolutional Neural Network-Aided Detection of Portal Hypertension in Patients With Cirrhosis.

Liu Y, Ning Z, Örmeci N, An W, Yu Q, Han K, Huang Y, Liu D, Liu F, Li Z, Ding H, Luo H, Zuo C, Liu C, Wang J, Zhang C, Ji J, Wang W, Wang Z, Wang W, Yuan M, Li L, Zhao Z, Wang G, Li M, Liu Q, Lei J, Liu C, Tang T, Akçalar S, Çelebioğlu E, Üstüner E, Bilgiç S, Ellik Z, Asiller ÖÖ, Liu Z, Teng G, Chen Y, Hou J, Li X, He X, Dong J, Tian J, Liang P, Ju S, Zhang Y, Qi X. Liu Y, et al. Among authors: wang g. Clin Gastroenterol Hepatol. 2020 Dec;18(13):2998-3007.e5. doi: 10.1016/j.cgh.2020.03.034. Epub 2020 Mar 21. Clin Gastroenterol Hepatol. 2020. PMID: 32205218

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