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Page 1
Bioactive Natural Product and Superacid Chemistry for Lead Compound Identification: A Case Study of Selective hCA III and L-Type Ca2+ Current Inhibitors for Hypotensive Agent Discovery.
Molecules. 2017 May 31;22(6):915. doi: 10.3390/molecules22060915.
Molecules. 2017.
PMID: 28561785
Free PMC article.
Review.
The hypotensive agent dodoneine inhibits L-type Ca2+ current with negative inotropic effect on rat heart.
Carré G, Carreyre H, Ouedraogo M, Becq F, Bois P, Thibaudeau S, Vandebrouck C, Bescond J.
Carré G, et al.
Eur J Pharmacol. 2014 Apr 5;728:119-27. doi: 10.1016/j.ejphar.2014.01.059. Epub 2014 Feb 5.
Eur J Pharmacol. 2014.
PMID: 24508520
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Vasorelaxation induced by dodoneine is mediated by calcium channels blockade and carbonic anhydrase inhibition on vascular smooth muscle cells.
Carre G, Ouedraogo M, Magaud C, Carreyre H, Becq F, Bois P, Supuran CT, Thibaudeau S, Vandebrouck C, Bescond J.
Carre G, et al.
J Ethnopharmacol. 2015 Jul 1;169:8-17. doi: 10.1016/j.jep.2015.03.037. Epub 2015 Apr 3.
J Ethnopharmacol. 2015.
PMID: 25847623
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Natural product hybrid and its superacid synthesized analogues: dodoneine and its derivatives show selective inhibition of carbonic anhydrase isoforms I, III, XIII and XIV.
Carreyre H, Coustard JM, Carré G, Vandebrouck C, Bescond J, Ouédraogo M, Marrot J, Vullo D, Supuran CT, Thibaudeau S.
Carreyre H, et al. Among authors: carre g.
Bioorg Med Chem. 2013 Jul 1;21(13):3790-4. doi: 10.1016/j.bmc.2013.04.041. Epub 2013 Apr 23.
Bioorg Med Chem. 2013.
PMID: 23685174
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