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Two cycles of plasma rich in growth factors (PRGF-Endoret) intra-articular injections improve stiffness and activities of daily living but not pain compared to one cycle on patients with symptomatic knee osteoarthritis.
Vaquerizo V, Padilla S, Aguirre JJ, Begoña L, Orive G, Anitua E. Vaquerizo V, et al. Knee Surg Sports Traumatol Arthrosc. 2018 Sep;26(9):2615-2621. doi: 10.1007/s00167-017-4565-z. Epub 2017 May 19. Knee Surg Sports Traumatol Arthrosc. 2018. PMID: 28526995 Clinical Trial.
Infiltration of plasma rich in growth factors enhances in vivo angiogenesis and improves reperfusion and tissue remodeling after severe hind limb ischemia.
Anitua E, Pelacho B, Prado R, Aguirre JJ, Sánchez M, Padilla S, Aranguren XL, Abizanda G, Collantes M, Hernandez M, Perez-Ruiz A, Peñuelas I, Orive G, Prosper F. Anitua E, et al. J Control Release. 2015 Mar 28;202:31-9. doi: 10.1016/j.jconrel.2015.01.029. Epub 2015 Jan 24. J Control Release. 2015. PMID: 25626084