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Targeted Isolation of Anti-inflammatory Lignans from Justicia aequilabris by Molecular Networking Approach.
E Silva JPR, Pereira LCO, Abreu LS, Lins FSV, de Souza TA, do Espírito-Santo RF, Barros RPC, Villarreal CF, de Melo JIM, Scotti MT, Costa VCO, Martorano LH, Dos Santos FM Jr, Filho RB, da Silva MS, Tavares JF. E Silva JPR, et al. J Nat Prod. 2022 Sep 23;85(9):2184-2191. doi: 10.1021/acs.jnatprod.2c00478. Epub 2022 Aug 23. J Nat Prod. 2022. PMID: 35998343 Review.
Three new lignans (aequilabrines A-C (1-3)) and three known compounds (lariciresinol-4'-O-beta-glucose (4), roseoside (5), and allantoin (6)) were obtained. ...
Three new lignans (aequilabrines A-C (1-3)) and three known compounds (lariciresinol-4'-O-beta-glucose (4), roseoside (5), and allant …
LASSBio-596: a New Pre-clinical Candidate for Rheumatoid Arthritis?
Viana MDM, de Lima AA, da Silva Neto GJ, da Silva SMA, Leite AB, Dos Santos EC, Bassi ÊJ, Campesatto EA, de Queiroz AC, Barreiro EJ, Lima LM, Alexandre-Moreira MS. Viana MDM, et al. Inflammation. 2022 Apr;45(2):528-543. doi: 10.1007/s10753-021-01564-2. Epub 2021 Oct 25. Inflammation. 2022. PMID: 34697722
In the abdominal writhing test, there was a dose-dependent inhibition, whose response occurred at the maximum dose (50 mg/kg, p.o.), used in the subsequent tests. LASSBio-596 also inhibited nociception induced by chemical (glutamate by 31.9%; and formalin, in both phases, …
In the abdominal writhing test, there was a dose-dependent inhibition, whose response occurred at the maximum dose (50 mg/kg, p.o.), …
Ozonized Water in Microbial Control: Analysis of the Stability, In Vitro Biocidal Potential, and Cytotoxicity.
Santos LMCD, Silva ESD, Oliveira FO, Rodrigues LAP, Neves PRF, Meira CS, Moreira GAF, Lobato GM, Nascimento C, Gerhardt M, Lessa AS, Mascarenhas LAB, Machado BAS. Santos LMCD, et al. Biology (Basel). 2021 Jun 12;10(6):525. doi: 10.3390/biology10060525. Biology (Basel). 2021. PMID: 34204772 Free PMC article.
The stability of O(3) was accessed following modifications of the physicochemical parameters of water, such as the temperature and pH, with or without buffering. ...Under the physicochemical conditions of 4 C and pH 5, O(3) remained the most stable and concentrated …
The stability of O(3) was accessed following modifications of the physicochemical parameters of water, such as the temperature and pH …
Anti-chikungunya virus seroprevalence in Indigenous groups in the São Francisco Valley, Brazil.
Nicacio JM, Khouri R, da Silva AML, Barral-Netto M, Lima JAC, Ladeia AMT, do Carmo RF, Armstrong ADC. Nicacio JM, et al. PLoS Negl Trop Dis. 2021 Jun 28;15(6):e0009468. doi: 10.1371/journal.pntd.0009468. eCollection 2021 Jun. PLoS Negl Trop Dis. 2021. PMID: 34181663 Free PMC article.
The study population included 433 individuals distributed as follows: 109 (25.2%) Truka, 272 (62.8%) Fulni-o, and 52 (12%) from the non-Indigenous urbanized control group. ...When the sample was stratified, positive CHIKV IgG was distributed as follows: no individuals in t …
The study population included 433 individuals distributed as follows: 109 (25.2%) Truka, 272 (62.8%) Fulni-o, and 52 (12%) from the n …
Antitumour Activity of the Microencapsulation of Annona vepretorum Essential Oil.
Bomfim LM, Menezes LR, Rodrigues AC, Dias RB, Rocha CA, Soares MB, Neto AF, Nascimento MP, Campos AF, Silva LC, Costa EV, Bezerra DP. Bomfim LM, et al. Basic Clin Pharmacol Toxicol. 2016 Mar;118(3):208-13. doi: 10.1111/bcpt.12488. Epub 2015 Oct 6. Basic Clin Pharmacol Toxicol. 2016. PMID: 26348780 Free article.
The essential oil included bicyclogermacrene (35.71%), spathulenol (18.89%), (E)-beta-ocimene (12.46%), alpha-phellandrene (8.08%), o-cymene (6.24%), germacrene D (3.27%) and alpha-pinene (2.18%) as major constituents. ...
The essential oil included bicyclogermacrene (35.71%), spathulenol (18.89%), (E)-beta-ocimene (12.46%), alpha-phellandrene (8.08%), o …
Nootkatone Inhibits Acute and Chronic Inflammatory Responses in Mice.
Bezerra Rodrigues Dantas L, Silva ALM, da Silva Júnior CP, Alcântara IS, Correia de Oliveira MR, Oliveira Brito Pereira Bezerra Martins A, Ribeiro-Filho J, Coutinho HDM, Rocha Santos Passos F, Quintans-Junior LJ, Alencar de Menezes IR, Pezzani R, Vitalini S. Bezerra Rodrigues Dantas L, et al. Molecules. 2020 May 7;25(9):2181. doi: 10.3390/molecules25092181. Molecules. 2020. PMID: 32392744 Free PMC article.
Effectiveness of ChAdOx1 vaccine in older adults during SARS-CoV-2 Gamma variant circulation in São Paulo.
Hitchings MDT, Ranzani OT, Dorion M, D'Agostini TL, de Paula RC, de Paula OFP, de Moura Villela EF, Torres MSS, de Oliveira SB, Schulz W, Almiron M, Said R, de Oliveira RD, Silva PV, de Araújo WN, Gorinchteyn JC, Andrews JR, Cummings DAT, Ko AI, Croda J. Hitchings MDT, et al. Nat Commun. 2021 Oct 28;12(1):6220. doi: 10.1038/s41467-021-26459-6. Nat Commun. 2021. PMID: 34711813 Free PMC article.
Urbanization and kidney dysfunction in Brazilian indigenous people: a burden for the youth.
Gomes OV, Guimarães MP, Nicacio JM, Morena L, Silva AMLD, Morais Junior JC, Souza CDF, Barral Netto M, Lima JAC, Armstrong ADC. Gomes OV, et al. Rev Assoc Med Bras (1992). 2023 Mar 3;69(2):240-245. doi: 10.1590/1806-9282.20220934. eCollection 2023. Rev Assoc Med Bras (1992). 2023. PMID: 36888763 Free PMC article.
METHODS: This is a cross-sectional study conducted between 2016 and 2017 in northeastern Brazil and includes individuals aged between 30 and 70 years from two specific indigenous groups who volunteered to participate in the study: the Fulni-o people (lowest degree of urban …
METHODS: This is a cross-sectional study conducted between 2016 and 2017 in northeastern Brazil and includes individuals aged between 30 and …
23 results