The Role of Pyrazolopyridine Derivatives on Different Steps of Herpes Simplex Virus Type-1 In Vitro Replicative Cycle.
Miranda MD, Chaves OA, Rosa AS, Azevedo AR, Pinheiro LCDS, Soares VC, Dias SSG, Abrantes JL, Bernardino AMR, Paixão ICP, Souza TML, Fontes CFL.
Miranda MD, et al.
Int J Mol Sci. 2022 Jul 23;23(15):8135. doi: 10.3390/ijms23158135.
Int J Mol Sci. 2022.
PMID: 35897709
Free PMC article.
We show that the 50% effective concentration (EC(50)) values of the compounds ARA-04, ARA-05, and AM-57 were 1.00 0.10, 1.00 0.05, and 0.70 0.10 M, respectively. These compounds presented high 50% cytotoxic concentration (CC(50)) values, which resulted in a selective index …
We show that the 50% effective concentration (EC(50)) values of the compounds ARA-04, ARA-05, and AM-57 were 1.00 0.10, 1.00 0.05, and 0.70 …