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Lysosome Fission: Planning for an Exit.
Trends Cell Biol. 2019 Aug;29(8):635-646. doi: 10.1016/j.tcb.2019.05.003. Epub 2019 Jun 3.
Trends Cell Biol. 2019.
PMID: 31171420
Review.
Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity.
Saffi GT, Wang CA, Mangialardi EM, Vacher J, Botelho RJ, Salmena L.
Saffi GT, et al.
J Biol Chem. 2022 Aug;298(8):102187. doi: 10.1016/j.jbc.2022.102187. Epub 2022 Jun 26.
J Biol Chem. 2022.
PMID: 35760104
Free PMC article.
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Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition.
Saffi GT, Tang E, Mamand S, Inpanathan S, Fountain A, Salmena L, Botelho RJ.
Saffi GT, et al.
PLoS One. 2021 Nov 23;16(11):e0259313. doi: 10.1371/journal.pone.0259313. eCollection 2021.
PLoS One. 2021.
PMID: 34813622
Free PMC article.
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Amyloid-β Inhibits PDGFβ Receptor Activation and Prevents PDGF-BBInduced Neuroprotection.
Liu H, Saffi GT, Vasefi MS, Choi Y, Kruk JS, Ahmed N, Gondora N, Mielke J, Leonenko Z, Beazely MA.
Liu H, et al. Among authors: saffi gt.
Curr Alzheimer Res. 2018;15(7):618-627. doi: 10.2174/1567205015666180110110321.
Curr Alzheimer Res. 2018.
PMID: 29332578
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Characterization of a PIP Binding Site in the N-Terminal Domain of V-ATPase a4 and Its Role in Plasma Membrane Association.
Chu A, Yao Y, Saffi GT, Chung JH, Botelho RJ, Glibowicka M, Deber CM, Manolson MF.
Chu A, et al. Among authors: saffi gt.
Int J Mol Sci. 2023 Mar 2;24(5):4867. doi: 10.3390/ijms24054867.
Int J Mol Sci. 2023.
PMID: 36902293
Free PMC article.
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