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Page 1
3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin analogues with antiproliferative activity.
Mar Drugs. 2015 Apr 3;13(4):1901-24. doi: 10.3390/md13041901.
Mar Drugs. 2015.
PMID: 25854642
Free PMC article.
Discovery of new G-quadruplex binding chemotypes.
Ohnmacht SA, Varavipour E, Nanjunda R, Pazitna I, Di Vita G, Gunaratnam M, Kumar A, Ismail MA, Boykin DW, Wilson WD, Neidle S.
Ohnmacht SA, et al. Among authors: di vita g.
Chem Commun (Camb). 2014 Jan 28;50(8):960-3. doi: 10.1039/c3cc48616h.
Chem Commun (Camb). 2014.
PMID: 24302123
Free PMC article.
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Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule.
Marchetti C, Zyner KG, Ohnmacht SA, Robson M, Haider SM, Morton JP, Marsico G, Vo T, Laughlin-Toth S, Ahmed AA, Di Vita G, Pazitna I, Gunaratnam M, Besser RJ, Andrade ACG, Diocou S, Pike JA, Tannahill D, Pedley RB, Evans TRJ, Wilson WD, Balasubramanian S, Neidle S.
Marchetti C, et al. Among authors: di vita g.
J Med Chem. 2018 Mar 22;61(6):2500-2517. doi: 10.1021/acs.jmedchem.7b01781. Epub 2018 Feb 7.
J Med Chem. 2018.
PMID: 29356532
Free PMC article.
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A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer.
Ohnmacht SA, Marchetti C, Gunaratnam M, Besser RJ, Haider SM, Di Vita G, Lowe HL, Mellinas-Gomez M, Diocou S, Robson M, Šponer J, Islam B, Pedley RB, Hartley JA, Neidle S.
Ohnmacht SA, et al. Among authors: di vita g.
Sci Rep. 2015 Jun 16;5:11385. doi: 10.1038/srep11385.
Sci Rep. 2015.
PMID: 26077929
Free PMC article.
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Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogues.
Carbone A, Parrino B, Di Vita G, Attanzio A, Spanò V, Montalbano A, Barraja P, Tesoriere L, Livrea MA, Diana P, Cirrincione G.
Carbone A, et al. Among authors: di vita g.
Mar Drugs. 2015 Jan 16;13(1):460-92. doi: 10.3390/md13010460.
Mar Drugs. 2015.
PMID: 25603343
Free PMC article.
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