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Page 1
Anticancer Therapeutic Strategies Targeting p53 Aggregation.
Ferretti GDS, Quarti J, Dos Santos G, Rangel LP, Silva JL. Ferretti GDS, et al. Int J Mol Sci. 2022 Sep 20;23(19):11023. doi: 10.3390/ijms231911023. Int J Mol Sci. 2022. PMID: 36232329 Free PMC article. Review.
Targeting Biomolecular Condensation and Protein Aggregation against Cancer.
Silva JL, Foguel D, Ferreira VF, Vieira TCRG, Marques MA, Ferretti GDS, Outeiro TF, Cordeiro Y, de Oliveira GAP. Silva JL, et al. Among authors: ferretti gds. Chem Rev. 2023 Jul 26;123(14):9094-9138. doi: 10.1021/acs.chemrev.3c00131. Epub 2023 Jun 28. Chem Rev. 2023. PMID: 37379327 Review.
Recent Synthetic Approaches towards Small Molecule Reactivators of p53.
Silva JL, Lima CGS, Rangel LP, Ferretti GDS, Pauli FP, Ribeiro RCB, da Silva TB, da Silva FC, Ferreira VF. Silva JL, et al. Among authors: ferretti gds. Biomolecules. 2020 Apr 20;10(4):635. doi: 10.3390/biom10040635. Biomolecules. 2020. PMID: 32326087 Free PMC article. Review.
Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands.
Petronilho EC, Pedrote MM, Marques MA, Passos YM, Mota MF, Jakobus B, de Sousa GDS, Pereira da Costa F, Felix AL, Ferretti GDS, Almeida FP, Cordeiro Y, Vieira TCRG, de Oliveira GAP, Silva JL. Petronilho EC, et al. Among authors: ferretti gds. Chem Sci. 2021 Apr 26;12(21):7334-7349. doi: 10.1039/d1sc01739j. Chem Sci. 2021. PMID: 34163823 Free PMC article.
Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex.
Beraldo FH, Ostapchenko VG, Caetano FA, Guimaraes AL, Ferretti GD, Daude N, Bertram L, Nogueira KO, Silva JL, Westaway D, Cashman NR, Martins VR, Prado VF, Prado MA. Beraldo FH, et al. Among authors: ferretti gd. J Biol Chem. 2016 Oct 14;291(42):21945-21955. doi: 10.1074/jbc.M116.738286. Epub 2016 Aug 25. J Biol Chem. 2016. PMID: 27563063 Free PMC article.
HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer.
Ferretti GDS, Quaas CE, Bertolini I, Zuccotti A, Saatci O, Kashatus JA, Sharmin S, Lu DY, Poli ANR, Quesnelle AF, Rodriguez-Blanco J, de Cubas AA, Hobbs GA, Liu Q, O'Bryan JP, Salvino JM, Kashatus DF, Sahin O, Barnoud T. Ferretti GDS, et al. Cell Death Differ. 2024 May 28. doi: 10.1038/s41418-024-01310-9. Online ahead of print. Cell Death Differ. 2024. PMID: 38802657
11 results