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A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice.
Lazo L, Bequet-Romero M, Lemos G, Musacchio A, Cabrales A, Bruno AJ, Ariel Espinosa L, Saloheimo M, Vitikainen M, Hernández A, Emalfarb M, Tchelet R, Suzarte E, Guillén G. Lazo L, et al. Among authors: lemos g. Vaccine. 2022 Feb 16;40(8):1162-1169. doi: 10.1016/j.vaccine.2022.01.007. Epub 2022 Jan 19. Vaccine. 2022. PMID: 35078661 Free PMC article.
Impact of the Route and Schedule of Immunization on the Serological and Virological Response of Chronic Hepatitis B Patients Treated with HeberNasvac.
Freyre FM, Aguiar JA, Cinza Z, Figueroa N, Diaz PA, Muzio VL, Lemos G, Freyre G, Coizeau E, Rodríguez C, Pentón E, Campos M, Santos IL, Mahtab MA, Akbar SMF, Guillen GE, Aguilar JC. Freyre FM, et al. Among authors: lemos g. Euroasian J Hepatogastroenterol. 2023 Jul-Dec;13(2):73-78. doi: 10.5005/jp-journals-10018-1402. Euroasian J Hepatogastroenterol. 2023. PMID: 38222949 Free PMC article.
Chimeric Antigen by the Fusion of SARS-CoV-2 Receptor Binding Domain with the Extracellular Domain of Human CD154: A Promising Improved Vaccine Candidate.
Ávalos I, Lao T, Rodríguez EM, Zamora Y, Rodríguez A, Ramón A, Lemos G, Cabrales A, Bequet-Romero M, Casillas D, Andújar I, Espinosa LA, González LJ, Alvarez Y, Carpio Y, Estrada MP. Ávalos I, et al. Among authors: lemos g. Vaccines (Basel). 2022 Jun 3;10(6):897. doi: 10.3390/vaccines10060897. Vaccines (Basel). 2022. PMID: 35746505 Free PMC article.
Murine monoclonal antibodies against RBD of the SARS-CoV-2 spike protein as useful analytical tools for subunit vaccine development and clinical trials.
Blanco OR, Dorta D, Hernández CA, Abreu D, Domínguez AG, Luna Y, Valdivia O, Pérez-Bernal M, Tamayo C, Lemos G, Pasarón IM, Pérez JJ, Benítez L, Bequet-Romero M, Fragas A, Cabrera Y, Pérez ER. Blanco OR, et al. Among authors: lemos g. J Immunol Methods. 2022 Jan;500:113195. doi: 10.1016/j.jim.2021.113195. Epub 2021 Nov 26. J Immunol Methods. 2022. PMID: 34843713 Free PMC article.
A first-in-class, first-in-human, phase I trial of CIGB-552, a synthetic peptide targeting COMMD1 to inhibit the oncogenic activity of NF-κB in patients with advanced solid tumors.
Vallespi MG, Mestre B, Marrero MA, Uranga R, Rey D, Lugiollo M, Betancourt M, Silva K, Corrales D, Lamadrid Y, Rodriguez Y, Maceo A, Chaviano PP, Lemos G, Cabrales A, Freyre FM, Santana H, Garay HE, Oliva B, Fernandez JR. Vallespi MG, et al. Among authors: lemos g. Int J Cancer. 2021 Sep 15;149(6):1313-1321. doi: 10.1002/ijc.33695. Epub 2021 May 27. Int J Cancer. 2021. PMID: 34019700 Free article. Clinical Trial.
HeberNasvac, a Therapeutic Vaccine for Chronic Hepatitis B, Stimulates Local and Systemic Markers of Innate Immunity: Potential Use in SARS-CoV-2 Postexposure Prophylaxis.
Fleites YA, Aguiar J, Cinza Z, Bequet M, Marrero E, Vizcaíno M, Esquivel I, Diaz M, Sin-Mayor A, Garcia M, Martinez SM, Beato A, Galarraga AG, Mendoza-Mari Y, Valdés I, García G, Lemos G, González I, Canaán-Haden C, Figueroa N, Oquendo R, Akbar SM, Mahtab MA, Uddin MH, Guillén GE, Muzio VL, Pentón E, Aguilar JC. Fleites YA, et al. Among authors: lemos g. Euroasian J Hepatogastroenterol. 2021 Jul-Dec;11(2):59-70. doi: 10.5005/jp-journals-10018-1344. Euroasian J Hepatogastroenterol. 2021. PMID: 34786358 Free PMC article.
Silent celiac disease in a cohort of healthy adults.
Galván JA, Lemos G, Fernández de Cossio ME, Ruenes C, Martínez Y, Tejeda Y, Roca J, Palenzuela DO, Novoa LI, Nazabal M. Galván JA, et al. Among authors: lemos g. Autoimmunity. 2009;42(8):705-8. doi: 10.3109/08916930903214009. Autoimmunity. 2009. PMID: 19886741