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MIJ821 (onfasprodil) in healthy volunteers: First-in-human, randomized, placebo-controlled study (single ascending dose and repeated intravenous dose).
Gomez-Mancilla B, Levy JA, Ganesan S, Faller T, Issachar G, Peremen Z, Laufer O, Shani-Hershkovich R, Biliouris K, Walker E, Healy MP, Sverdlov O, Desai S, Ghaemi SN, Cha JH, Shanker YG. Gomez-Mancilla B, et al. Among authors: issachar g. Clin Transl Sci. 2023 Nov;16(11):2236-2252. doi: 10.1111/cts.13623. Epub 2023 Oct 10. Clin Transl Sci. 2023. PMID: 37817426 Free PMC article. Clinical Trial.
Identification of an early-stage Parkinson's disease neuromarker using event-related potentials, brain network analytics and machine-learning.
Hassin-Baer S, Cohen OS, Israeli-Korn S, Yahalom G, Benizri S, Sand D, Issachar G, Geva AB, Shani-Hershkovich R, Peremen Z. Hassin-Baer S, et al. Among authors: issachar g. PLoS One. 2022 Jan 7;17(1):e0261947. doi: 10.1371/journal.pone.0261947. eCollection 2022. PLoS One. 2022. PMID: 34995285 Free PMC article. Clinical Trial.
A Study of Novel Exploratory Tools, Digital Technologies, and Central Nervous System Biomarkers to Characterize Unipolar Depression.
Sverdlov O, Curcic J, Hannesdottir K, Gou L, De Luca V, Ambrosetti F, Zhang B, Praestgaard J, Vallejo V, Dolman A, Gomez-Mancilla B, Biliouris K, Deurinck M, Cormack F, Anderson JJ, Bott NT, Peremen Z, Issachar G, Laufer O, Joachim D, Jagesar RR, Jongs N, Kas MJ, Zhuparris A, Zuiker R, Recourt K, Zuilhof Z, Cha JH, Jacobs GE. Sverdlov O, et al. Among authors: issachar g. Front Psychiatry. 2021 May 6;12:640741. doi: 10.3389/fpsyt.2021.640741. eCollection 2021. Front Psychiatry. 2021. PMID: 34025472 Free PMC article.