Population Genetics of the European Roma-A Review

Genes (Basel). 2022 Nov 8;13(11):2068. doi: 10.3390/genes13112068.

Abstract

The Roma are a group of populations with a common origin that share the Romani identity and cultural heritage. Their genetic history has been inferred through multiple studies based on uniparental and autosomal markers, and current genomic data have provided novel insights into their genetic background. This review was prompted by two factors: (i) new developments to estimate the genetic structure of the Roma at a fine-scale resolution have precisely identified the ancestral components and traced migrations that were previously documented only in historical sources, clarifying and solving debates on the origins and the diaspora of the Roma; (ii) while there has been an effort to review the health determinants of the Roma, the increasing literature on their population genetics has not been subjected to a dedicated review in the last two decades. We believe that a summary on the state of the art will benefit both the public and scholars that are approaching the subject.

Keywords: Romani; bottleneck; founder event; genetic structure; genomics; population genetics.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genetics, Population
  • Haplotypes
  • Human Migration
  • Humans
  • Roma* / genetics

Grants and funding

This work was supported by the Spanish Ministry of Science, Innovation and Universities (MCIU) and the Agencia Estatal de Investigación (AEI) [PID2019-106485GB-I00/AEI/10.13039/501100011033]; and “Unidad de Excelencia María de Maeztu” [AEI, CEX2018-000792-M].