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Automated manufacture of ΔNPM1 TCR-engineered T cells for AML therapy.
Yonezawa Ogusuku IE, Herbel V, Lennartz S, Brandes C, Argiro E, Fabian C, Hauck C, Hoogstraten C, Veld S, Hageman L, Teppert K, Koutsoumpli G, Griffioen M, Mockel-Tenbrinck N, Schaser T, de Groot R, Johnston ICD, Lock D. Yonezawa Ogusuku IE, et al. Among authors: koutsoumpli g. Mol Ther Methods Clin Dev. 2024 Feb 27;32(2):101224. doi: 10.1016/j.omtm.2024.101224. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38516690 Free PMC article.
An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML.
van der Lee DI, Koutsoumpli G, Reijmers RM, Honders MW, de Jong RCM, Remst DFG, Wachsmann TLA, Hagedoorn RS, Franken KLMC, Kester MGD, Harber KJ, Roelofsen LM, Schouten AM, Mulder A, Drijfhout JW, Veelken H, van Veelen PA, Heemskerk MHM, Falkenburg JHF, Griffioen M. van der Lee DI, et al. Among authors: koutsoumpli g. Cancers (Basel). 2021 Oct 27;13(21):5390. doi: 10.3390/cancers13215390. Cancers (Basel). 2021. PMID: 34771556 Free PMC article.
Expanding the repertoire reveals recurrent, cryptic and hematopoietic HLA class I minor histocompatibility antigens.
Fuchs KJ, van de Meent M, Honders MW, Khatri I, Kester MGD, Koster EAS, Koutsoumpli G, de Ru AH, Van Bergen CAM, van Veelen PA, 't Hoen PAC, van Balen P, van den Akker EB, Veelken H, Halkes CJJ, Falkenburg JHF, Griffioen M. Fuchs KJ, et al. Among authors: koutsoumpli g. Blood. 2024 Mar 1:blood.2023022343. doi: 10.1182/blood.2023022343. Online ahead of print. Blood. 2024. PMID: 38427583 Free article.