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Dose Finding and Food Effect Studies of a Novel Abiraterone Acetate Formulation for Oral Suspension in Comparison to a Reference Formulation in Healthy Male Subjects.
Jordán T, Basa-Dénes O, Angi R, Orosz J, Ötvös Z, Ujhelyi A, Filipcsei G, Molnár L, Solymosi T, Glavinas H, Capone D, Whitfield N, McDermott J, McKenzie L, Shurety L, Duus EM. Jordán T, et al. Among authors: filipcsei g. Pharmaceutics. 2021 Dec 16;13(12):2171. doi: 10.3390/pharmaceutics13122171. Pharmaceutics. 2021. PMID: 34959452 Free PMC article.
Novel formulation of abiraterone acetate might allow significant dose reduction and eliminates substantial positive food effect.
Solymosi T, Ötvös Z, Angi R, Ordasi B, Jordán T, Molnár L, McDermott J, Zann V, Church A, Mair S, Filipcsei G, Heltovics G, Glavinas H. Solymosi T, et al. Among authors: filipcsei g. Cancer Chemother Pharmacol. 2017 Oct;80(4):723-728. doi: 10.1007/s00280-017-3406-6. Epub 2017 Aug 3. Cancer Chemother Pharmacol. 2017. PMID: 28776077 Clinical Trial.
Development of an abiraterone acetate formulation with improved oral bioavailability guided by absorption modeling based on in vitro dissolution and permeability measurements.
Solymosi T, Ötvös Z, Angi R, Ordasi B, Jordán T, Semsey S, Molnár L, Ránky S, Filipcsei G, Heltovics G, Glavinas H. Solymosi T, et al. Among authors: filipcsei g. Int J Pharm. 2017 Oct 30;532(1):427-434. doi: 10.1016/j.ijpharm.2017.09.031. Epub 2017 Sep 15. Int J Pharm. 2017. PMID: 28919099
Swelling kinetics of anisotropic filler loaded PDMS networks.
Hajsz T, Csetneki I, Filipcsei G, Zrinyi M. Hajsz T, et al. Among authors: filipcsei g. Phys Chem Chem Phys. 2006 Feb 28;8(8):977-84. doi: 10.1039/b511995b. Epub 2005 Dec 8. Phys Chem Chem Phys. 2006. PMID: 16482340