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Showing results for ge gen qin
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Systems pharmacology reveals the mechanism of activity of Ge-Gen-Qin-Lian decoction against LPS-induced acute lung injury: A novel strategy for exploring active components and effective mechanism of TCM formulae.
Ding Z, Zhong R, Yang Y, Xia T, Wang W, Wang Y, Xing N, Luo Y, Li S, Shang L, Shu Z. Ding Z, et al. Pharmacol Res. 2020 Jun;156:104759. doi: 10.1016/j.phrs.2020.104759. Epub 2020 Mar 19. Pharmacol Res. 2020. PMID: 32200026
Acute lung injury (ALI), a severe and life-threatening inflammation of the lung, with high morbidity and mortality, underscoring the urgent need for novel treatments. Ge-Gen-Qin-Lian decoction (GQD), a classic Chinese herbal formula, has been widely used to t …
Acute lung injury (ALI), a severe and life-threatening inflammation of the lung, with high morbidity and mortality, underscoring the urgent …
Uncovering the mechanism of Ge-Gen-Qin-Lian decoction for treating ulcerative colitis based on network pharmacology and molecular docking verification.
Xu L, Zhang J, Wang Y, Zhang Z, Wang F, Tang X. Xu L, et al. Biosci Rep. 2021 Feb 26;41(2):BSR20203565. doi: 10.1042/BSR20203565. Biosci Rep. 2021. PMID: 33409535 Free PMC article.
BACKGROUND: Ge-Gen-Qin-Lian Decoction (GGQLD), a traditional Chinese medicine (TCM) formula, has been widely used for ulcerative colitis (UC) in China, but the pharmacological mechanisms remain unclear. ...
BACKGROUND: Ge-Gen-Qin-Lian Decoction (GGQLD), a traditional Chinese medicine (TCM) formula, has been widely used for u …
Antidiabetic Micro-/Nanoaggregates from Ge-Gen-Qin-Lian-Tang Decoction Increase Absorption of Baicalin and Cellular Antioxidant Activity In Vitro.
Lin D, Du Q, Wang H, Gao G, Zhou J, Ke L, Chen T, Shaw C, Rao P. Lin D, et al. Biomed Res Int. 2017;2017:9217912. doi: 10.1155/2017/9217912. Epub 2017 Jul 17. Biomed Res Int. 2017. PMID: 28798936 Free PMC article.
The antidiabetic effects of Ge-Gen-Qin-Lian-Tang decoction (GQD) have been proven clinically. In a pharmacological study conducted on STZ-induced diabetic rats, the constitutive aggregates/sediments of Ge-Gen-Qin-Lian-Tang decoction exhib …
The antidiabetic effects of Ge-Gen-Qin-Lian-Tang decoction (GQD) have been proven clinically. In a pharmacological stud …
Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway.
Liu H, Liu H, Zhou Z, Parise RA, Chu E, Schmitz JC. Liu H, et al. Cell Commun Signal. 2018 Feb 20;16(1):7. doi: 10.1186/s12964-018-0218-1. Cell Commun Signal. 2018. PMID: 29458395 Free PMC article.
METHODS: Cell proliferation and clonogenic assays, cell cycle analysis, immunoblot analysis and qRT-PCR were performed to investigate the mechanism(s) of action of the most active formula Huang-Qin-Ge-Gen-Tang (HQGGT) on growth of human CRC cells. In vivo ani …
METHODS: Cell proliferation and clonogenic assays, cell cycle analysis, immunoblot analysis and qRT-PCR were performed to investigate the me …
Metabonomic Study on the Plasma of High-Fat Diet-Induced Dyslipidemia Rats Treated with Ge Gen Qin Lian Decoction by Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry.
Xu Z, Sheng Y, Zeng G, Zeng Z, Li B, Jiang L, Xu G, Zhang Q. Xu Z, et al. Evid Based Complement Alternat Med. 2021 Jun 5;2021:6692456. doi: 10.1155/2021/6692456. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 34194524 Free PMC article.
The changes in endogenous metabolites in the plasma of high-fat diet-induced dyslipidemia rats treated with Ge Gen Qin Lian Decoction (GGQLD) were studied to elucidate the therapeutic effects and mechanism of action of GGQLD in dyslipidemia. ...
The changes in endogenous metabolites in the plasma of high-fat diet-induced dyslipidemia rats treated with Ge Gen Qin …
A rapid UPLC method for simultaneous determination of eleven components in 'Ge-Gen-Qin-Lian' decoction.
An R, You L, Zhang Y, Wang X, Ma Y. An R, et al. Pharmacogn Mag. 2014 Oct;10(40):464-9. doi: 10.4103/0973-1296.141821. Pharmacogn Mag. 2014. PMID: 25422547 Free PMC article.
BACKGROUND: 'Ge-Gen-Qin-Lian' Decoction derived from 'Shang-Han-Lun' compiled by Zhang Zhongjing. ...The validated method was successfully applied to simultaneous analysis of these active components in 'Ge-Gen-Qin-Lian' decoction....
BACKGROUND: 'Ge-Gen-Qin-Lian' Decoction derived from 'Shang-Han-Lun' compiled by Zhang Zhongjing. ...The validated meth …
Comparing the antidiabetic effects and chemical profiles of raw and fermented Chinese Ge-Gen-Qin-Lian decoction by integrating untargeted metabolomics and targeted analysis.
Yan Y, Du C, Li Z, Zhang M, Li J, Jia J, Li A, Qin X, Song Q. Yan Y, et al. Chin Med. 2018 Oct 26;13:54. doi: 10.1186/s13020-018-0208-7. eCollection 2018. Chin Med. 2018. PMID: 30386417 Free PMC article.
Various beneficial effects of fermentation for applications in TCM or herbals have been reported, such as enhanced anti-ovarian cancer, antioxidative activity, and neuroprotective effects. Ge-Gen-Qin-Lian decoction (GQD), a classic TCM formula, has been used …
Various beneficial effects of fermentation for applications in TCM or herbals have been reported, such as enhanced anti-ovarian cancer, anti …
Metabonomic study on the plasma of streptozotocin-induced diabetic rats treated with Ge Gen Qin Lian Decoction by ultra high performance liquid chromatography-mass spectrometry.
Zhang Q, Xu G, Li J, Guo X, Wang H, Li B, Tu J, Zhang H. Zhang Q, et al. J Pharm Biomed Anal. 2016 Feb 20;120:175-80. doi: 10.1016/j.jpba.2015.12.031. Epub 2015 Dec 22. J Pharm Biomed Anal. 2016. PMID: 26744987
Changes in endogenous metabolites in the plasma of streptozotocin (STZ)-induced diabetic rats treated with Ge Gen Qin Lian Decoction (GGQLD) were studied. The endogenous compounds in plasma were detected using ultra high performance liquid chromatography coup …
Changes in endogenous metabolites in the plasma of streptozotocin (STZ)-induced diabetic rats treated with Ge Gen Qin L …
A network pharmacology approach to determine active compounds and action mechanisms of ge-gen-qin-lian decoction for treatment of type 2 diabetes.
Li H, Zhao L, Zhang B, Jiang Y, Wang X, Guo Y, Liu H, Li S, Tong X. Li H, et al. Evid Based Complement Alternat Med. 2014;2014:495840. doi: 10.1155/2014/495840. Epub 2014 Jan 16. Evid Based Complement Alternat Med. 2014. PMID: 24527048 Free PMC article.
In this study, we used a network pharmacology approach we previously developed to help determine the potential antidiabetic ingredients from the traditional Ge-Gen-Qin-Lian decoction (GGQLD) formula. We predicted the target profiles of all available GGQLD ing …
In this study, we used a network pharmacology approach we previously developed to help determine the potential antidiabetic ingredients from …
29 results