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Year Number of Results
1981 1
1984 3
1986 1
1987 4
1988 5
1989 8
1990 5
1991 6
1992 30
1993 23
1994 28
1995 31
1996 41
1997 45
1998 57
1999 64
2000 82
2001 89
2002 130
2003 183
2004 192
2005 228
2006 255
2007 305
2008 329
2009 408
2010 432
2011 511
2012 659
2013 794
2014 909
2015 1056
2016 1095
2017 1163
2018 1192
2019 1415
2020 1634
2021 1846
2022 1928
2023 1785
2024 885

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17,794 results

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The following term was not found in PubMed: Jean-Win
Page 1
The Function of RAS Mutation in Cancer and Advances in its Drug Research.
Chen S, Li F, Xu D, Hou K, Fang W, Li Y. Chen S, et al. Curr Pharm Des. 2019;25(10):1105-1114. doi: 10.2174/1381612825666190506122228. Curr Pharm Des. 2019. PMID: 31057104 Review.
RAS (H-ras, K-ras, and N-ras), as the second largest mutated gene driver in various human cancers, has long been a vital research target for cancer. ...In this paper, we started with the role of normal and mutant RAS genes in cancer, elucidated the relevant RAS regu …
RAS (H-ras, K-ras, and N-ras), as the second largest mutated gene driver in various human cancers, has long been a vital research tar …
Replacement of stacked transgenes in planta.
Chen W, Kaur G, Hou L, Li R, Ow DW. Chen W, et al. Plant Biotechnol J. 2019 Nov;17(11):2029-2031. doi: 10.1111/pbi.13172. Epub 2019 Jun 12. Plant Biotechnol J. 2019. PMID: 31127663 Free PMC article. No abstract available.
PHF6 maintains acute myeloid leukemia via regulating NF-κB signaling pathway.
Hou S, Wang X, Guo T, Lan Y, Yuan S, Yang S, Zhao F, Fang A, Liu N, Yang W, Chu Y, Jiang E, Cheng T, Sun X, Yuan W. Hou S, et al. Leukemia. 2023 Aug;37(8):1626-1637. doi: 10.1038/s41375-023-01953-6. Epub 2023 Jul 1. Leukemia. 2023. PMID: 37393343 Free PMC article.
Here with in vivo and in vitro models, we demonstrate that the Plant homeodomain finger gene 6 (PHF6) plays an important role in apoptosis and proliferation in myeloid leukemia. ...
Here with in vivo and in vitro models, we demonstrate that the Plant homeodomain finger gene 6 (PHF6) plays an important role in apop …
Inflammatory Immune-Associated eRNA: Mechanisms, Functions and Therapeutic Prospects.
Wan L, Li W, Meng Y, Hou Y, Chen M, Xu B. Wan L, et al. Front Immunol. 2022 Apr 19;13:849451. doi: 10.3389/fimmu.2022.849451. eCollection 2022. Front Immunol. 2022. PMID: 35514959 Free PMC article. Review.
It has been shown that both active enhancers and intranuclear eRNAs are preferentially expressed over inflammation-related genes in response to inflammatory stimuli, suggesting that enhancer transcription events and their products influence the expression and function of i …
It has been shown that both active enhancers and intranuclear eRNAs are preferentially expressed over inflammation-related genes in r …
Spirits in the Material World: Enhancer RNAs in Transcriptional Regulation.
Hou TY, Kraus WL. Hou TY, et al. Trends Biochem Sci. 2021 Feb;46(2):138-153. doi: 10.1016/j.tibs.2020.08.007. Epub 2020 Sep 1. Trends Biochem Sci. 2021. PMID: 32888773 Free PMC article. Review.
Responses to developmental and environmental cues depend on precise spatiotemporal control of gene transcription. Enhancers, which comprise DNA elements bound by regulatory proteins, can activate target genes in response to these external signals. Recent studies hav …
Responses to developmental and environmental cues depend on precise spatiotemporal control of gene transcription. Enhancers, which co …
Comprehensive mapping of alternative polyadenylation site usage and its dynamics at single-cell resolution.
Wang J, Chen W, Yue W, Hou W, Rao F, Zhong H, Qi Y, Hong N, Ni T, Jin W. Wang J, et al. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2113504119. doi: 10.1073/pnas.2113504119. Epub 2022 Dec 1. Proc Natl Acad Sci U S A. 2022. PMID: 36454750 Free PMC article.
Interestingly, cell cycle genes were significantly enriched in genes with high variation in polyA site usages. Furthermore, the 414 genes showing a polyA site usage switch after cell synchronization enriched cell cycle genes, while the differentially e …
Interestingly, cell cycle genes were significantly enriched in genes with high variation in polyA site usages. Furthermore, th …
Comprehensive systematic review and meta-analysis of the association between common genetic variants and autism spectrum disorder.
Fang Y, Cui Y, Yin Z, Hou M, Guo P, Wang H, Liu N, Cai C, Wang M. Fang Y, et al. Gene. 2023 Dec 15;887:147723. doi: 10.1016/j.gene.2023.147723. Epub 2023 Aug 18. Gene. 2023. PMID: 37598788 Review.
Odds ratio and 95 % confidence interval were used as effect indexes to evaluate the association between the SNPs of candidate genes and the risk of ASD. Heterogeneity was explored through subgroup, sensitivity, and meta-regression analyses. ...In addition, TSA analysis wer …
Odds ratio and 95 % confidence interval were used as effect indexes to evaluate the association between the SNPs of candidate genes a …
Nuclear factors: roles related to mitochondrial deafness.
Luo LF, Hou CC, Yang WX. Luo LF, et al. Gene. 2013 May 15;520(2):79-89. doi: 10.1016/j.gene.2013.03.041. Epub 2013 Mar 17. Gene. 2013. PMID: 23510774 Review.
The specific nuclear genes involved in HL can be classified into two categories depending on whether mitochondrial gene mutations co-exist (modifier genes) or not (deafness-causing genes). TFB1M, MTO1, GTPBP3, and TRMU are modifier genes. A muta …
The specific nuclear genes involved in HL can be classified into two categories depending on whether mitochondrial gene mutati …
Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING.
Hou MH, Wang YC, Yang CS, Liao KF, Chang JW, Shih O, Yeh YQ, Sriramoju MK, Weng TW, Jeng US, Hsu SD, Chen Y. Hou MH, et al. Nat Commun. 2023 Dec 21;14(1):8519. doi: 10.1038/s41467-023-44052-x. Nat Commun. 2023. PMID: 38129386 Free PMC article.
The cyclic GMP-AMP synthase (cGAS)/stimulator of interferon gene (STING) signaling pathway plays a critical protective role against viral infections. ...
The cyclic GMP-AMP synthase (cGAS)/stimulator of interferon gene (STING) signaling pathway plays a critical protective role against v …
Size-dependent enhancement on conjugative transfer of antibiotic resistance genes by micro/nanoplastics.
Zha Y, Li Z, Zhong Z, Ruan Y, Sun L, Zuo F, Li L, Hou S. Zha Y, et al. J Hazard Mater. 2022 Jun 5;431:128561. doi: 10.1016/j.jhazmat.2022.128561. Epub 2022 Feb 23. J Hazard Mater. 2022. PMID: 35278945
We found that influence of MNPs on gene transfer was size-dependent. Small MNPs (10 nm in radius) caused an increase and then a decrease in gene transfer efficiency with their concentration increasing. Moderate-sized MNPs (50 nm in radius) caused an increase in g …
We found that influence of MNPs on gene transfer was size-dependent. Small MNPs (10 nm in radius) caused an increase and then a decre …
17,794 results
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