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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1957 1
1959 2
1960 1
1965 1
1967 6
1968 3
1970 6
1971 7
1972 6
1973 7
1974 5
1975 10
1976 13
1977 14
1978 27
1979 17
1980 28
1981 35
1982 37
1983 38
1984 35
1985 48
1986 51
1987 55
1988 67
1989 77
1990 90
1991 97
1992 95
1993 135
1994 109
1995 139
1996 116
1997 117
1998 153
1999 143
2000 165
2001 172
2002 209
2003 159
2004 219
2005 269
2006 253
2007 271
2008 251
2009 255
2010 286
2011 334
2012 352
2013 351
2014 359
2015 346
2016 336
2017 337
2018 342
2019 346
2020 379
2021 380
2022 271
2023 298
2024 101

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8,070 results

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37 articles found by citation matching
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Page 1
Tumour suppressor genes.
Klein G. Klein G. J Cell Sci Suppl. 1988;10:171-80. doi: 10.1242/jcs.1988.supplement_10.13. J Cell Sci Suppl. 1988. PMID: 3077935 Review.
Such tumour suppressor genes will probably turn out to be as, if not more, diversified as the oncogenes. Consideration of both kinds of genes may reveal common or interrelated functional properties....
Such tumour suppressor genes will probably turn out to be as, if not more, diversified as the oncogenes. Consideration of both kinds …
Intrachromosomal Recombination in Yeast.
Epshtein A, Symington LS, Klein HL. Epshtein A, et al. Methods Mol Biol. 2021;2153:193-200. doi: 10.1007/978-1-0716-0644-5_14. Methods Mol Biol. 2021. PMID: 32840781
This chapter describes commonly used types of reporters where a gene is duplicated as direct repeats and both copies are mutated with different mutations, rendering the cell defective for the gene and auxotrophic for the gene product. Recombination between th …
This chapter describes commonly used types of reporters where a gene is duplicated as direct repeats and both copies are mutated with …
Gene family information facilitates variant interpretation and identification of disease-associated genes in neurodevelopmental disorders.
Lal D, May P, Perez-Palma E, Samocha KE, Kosmicki JA, Robinson EB, Møller RS, Krause R, Nürnberg P, Weckhuysen S, De Jonghe P, Guerrini R, Niestroj LM, Du J, Marini C; EuroEPINOMICS-RES Consortium; Ware JS, Kurki M, Gormley P, Tang S, Wu S, Biskup S, Poduri A, Neubauer BA, Koeleman BPC, Helbig KL, Weber YG, Helbig I, Majithia AR, Palotie A, Daly MJ. Lal D, et al. Genome Med. 2020 Mar 17;12(1):28. doi: 10.1186/s13073-020-00725-6. Genome Med. 2020. PMID: 32183904 Free PMC article.
We developed a gene family de novo enrichment framework that identified 43 exome-wide enriched gene families including 98 de novo variant carrying genes in NDD patients of which 28 represent novel candidate genes for NDD which are brain expressed and u …
We developed a gene family de novo enrichment framework that identified 43 exome-wide enriched gene families including 98 de n …
Evolutionary aspects of cancer resistance.
Klein G. Klein G. Semin Cancer Biol. 2014 Apr;25:10-4. doi: 10.1016/j.semcancer.2014.01.001. Epub 2014 Jan 15. Semin Cancer Biol. 2014. PMID: 24440448 Review.
The inhibitory capacity of the fibroblast differs depending on the site of origin, and is also different between normal and cancer derived stroma cells. Preliminary gene analysis points to major differences in gene expression in between inhibitory and non-inhibitory …
The inhibitory capacity of the fibroblast differs depending on the site of origin, and is also different between normal and cancer derived s …
Identifying modules of cooperating cancer drivers.
Klein MI, Cannataro VL, Townsend JP, Newman S, Stern DF, Zhao H. Klein MI, et al. Mol Syst Biol. 2021 Mar;17(3):e9810. doi: 10.15252/msb.20209810. Mol Syst Biol. 2021. PMID: 33769711 Free PMC article.
The tomato cis-prenyltransferase gene family.
Akhtar TA, Matsuba Y, Schauvinhold I, Yu G, Lees HA, Klein SE, Pichersky E. Akhtar TA, et al. Plant J. 2013 Feb;73(4):640-52. doi: 10.1111/tpj.12063. Epub 2012 Dec 31. Plant J. 2013. PMID: 23134568 Free article.
Six of the SlCPT genes encode proteins with N-terminal targeting sequences, which, when fused to GFP, mediated GFP transport to the plastids of Arabidopsis protoplasts. ...RNAi-mediated suppression of NDPS1 led to a large decrease in beta-phellandrene (which is produced fr …
Six of the SlCPT genes encode proteins with N-terminal targeting sequences, which, when fused to GFP, mediated GFP transport to the p …
An Ac/Ds-mediated gene trap system for functional genomics in barley.
Lazarow K, Lütticke S. Lazarow K, et al. BMC Genomics. 2009 Jan 29;10:55. doi: 10.1186/1471-2164-10-55. BMC Genomics. 2009. PMID: 19178688 Free PMC article.
BACKGROUND: Gene trapping is a powerful tool for gene discovery and functional genomics in both animals and plants. ...Consequently, detection of reporter gene expression allows the identification of genes based on their expression pattern. ...
BACKGROUND: Gene trapping is a powerful tool for gene discovery and functional genomics in both animals and plants. ...Consequ …
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.
Kalman LV, Agúndez J, Appell ML, Black JL, Bell GC, Boukouvala S, Bruckner C, Bruford E, Caudle K, Coulthard SA, Daly AK, Del Tredici A, den Dunnen JT, Drozda K, Everts RE, Flockhart D, Freimuth RR, Gaedigk A, Hachad H, Hartshorne T, Ingelman-Sundberg M, Klein TE, Lauschke VM, Maglott DR, McLeod HL, McMillin GA, Meyer UA, Müller DJ, Nickerson DA, Oetting WS, Pacanowski M, Pratt VM, Relling MV, Roberts A, Rubinstein WS, Sangkuhl K, Schwab M, Scott SA, Sim SC, Thirumaran RK, Toji LH, Tyndale RF, van Schaik R, Whirl-Carrillo M, Yeo K, Zanger UM. Kalman LV, et al. Clin Pharmacol Ther. 2016 Feb;99(2):172-85. doi: 10.1002/cpt.280. Epub 2015 Nov 20. Clin Pharmacol Ther. 2016. PMID: 26479518 Free PMC article. Review.
In addition, PGx analysis may detect different sets of variants for each gene, which can affect interpretation of results. This practice has caused confusion and may thereby impede the adoption of clinical PGx testing. ...
In addition, PGx analysis may detect different sets of variants for each gene, which can affect interpretation of results. This pract …
Search for unknown tumor-antagonizing genes.
Imreh S, Klein G, Zabarovsky ER. Imreh S, et al. Genes Chromosomes Cancer. 2003 Dec;38(4):307-21. doi: 10.1002/gcc.10271. Genes Chromosomes Cancer. 2003. PMID: 14566849 Review.
The loss of heterozygosity (LOH) technique, introduced by Cavenee and colleagues, was an important milestone toward the confirmation of Knudson's hypothesis and the identification of the gene. Subsequently, the LOH technique has provided important clues that have led to th …
The loss of heterozygosity (LOH) technique, introduced by Cavenee and colleagues, was an important milestone toward the confirmation of Knud …
8,070 results