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Page 1
Showing results for gene bax
Search for Gege Bao instead (1 results)
Puerarin attenuates neurological deficits via Bcl-2/Bax/cleaved caspase-3 and Sirt3/SOD2 apoptotic pathways in subarachnoid hemorrhage mice.
Zhang Y, Yang X, Ge X, Zhang F. Zhang Y, et al. Biomed Pharmacother. 2019 Jan;109:726-733. doi: 10.1016/j.biopha.2018.10.161. Epub 2018 Nov 5. Biomed Pharmacother. 2019. PMID: 30551525 Free article.
But whether puerarin can reduce brain nerve damage after SAH is not clear.In this study, we hypothesized that puerarin had the neuroprotective effect after SAH, and this protection could be mediated by bothBcl-2/Bax/Cleaved caspase-3 and SIRT3/SOD2 apoptotic signaling path …
But whether puerarin can reduce brain nerve damage after SAH is not clear.In this study, we hypothesized that puerarin had the neuroprotecti …
Mammalian pro-apoptotic bax gene enhances tobacco resistance to pathogens.
Dong S, Zhang Z, Zheng X, Wang Y. Dong S, et al. Plant Cell Rep. 2008 Sep;27(9):1559-69. doi: 10.1007/s00299-008-0554-5. Epub 2008 May 29. Plant Cell Rep. 2008. PMID: 18509654
In this study, a rice phenylalanine ammonia-lyase promoter is used to regulate the expression of the mouse pro-apoptotic bax gene in transgenic tobacco plants. Ectopic expression of the bax negatively affects the growth of transgenic plants. ...These results …
In this study, a rice phenylalanine ammonia-lyase promoter is used to regulate the expression of the mouse pro-apoptotic bax gene …
Impaired BAX protein expression in breast cancer: mutational analysis of the BAX and the p53 gene.
Sturm I, Papadopoulos S, Hillebrand T, Benter T, Lück HJ, Wolff G, Dörken B, Daniel PT. Sturm I, et al. Int J Cancer. 2000 Aug 15;87(4):517-21. doi: 10.1002/1097-0215(20000815)87:4<517::aid-ijc9>3.0.co;2-b. Int J Cancer. 2000. PMID: 10918191 Free article.
The expression of BAX protein was assessed by immunohistochemistry. In addition, we screened for mutations in the exons 5-8 of the p53 gene by SSCP-PCR to assess whether mutations in the DNA-binding domain of this upstream regulator of BAX gene transcr …
The expression of BAX protein was assessed by immunohistochemistry. In addition, we screened for mutations in the exons 5-8 of the p5 …
Gene expression patterns of the Bcl-2 and Bax genes in preterm birth.
Demendi C, Börzsönyi B, Végh V, Nagy ZB, Rigó J Jr, Pajor A, Joó JG. Demendi C, et al. Acta Obstet Gynecol Scand. 2012 Oct;91(10):1212-7. doi: 10.1111/j.1600-0412.2012.01428.x. Epub 2012 Aug 13. Acta Obstet Gynecol Scand. 2012. PMID: 22524261 Free article.
OBJECTIVE: The apoptotic genes Bax and Bcl-2 are both involved in the pathogenesis of preterm delivery in conjunction with additional factors. We characterized gene expression patterns of these apoptotic regulatory genes as well as relevant environment …
OBJECTIVE: The apoptotic genes Bax and Bcl-2 are both involved in the pathogenesis of preterm delivery in conjunction with add …
Bax-induced apoptosis as a novel gene therapy approach for carcinoma of the cervix.
Huh WK, Gomez-Navarro J, Arafat WO, Xiang J, Mahasreshti PJ, Alvarez RD, Barnes MN, Curiel DT. Huh WK, et al. Gynecol Oncol. 2001 Nov;83(2):370-7. doi: 10.1006/gyno.2001.6403. Gynecol Oncol. 2001. PMID: 11606099
We generated a recombinant adenoviral vector that encodes the bax gene under inducible conditions. To this end, expression of this pro-apoptotic gene was controlled by a Cre-LoxP system. ...These data suggest that bax may be a candidate for human ge …
We generated a recombinant adenoviral vector that encodes the bax gene under inducible conditions. To this end, expression of …
Investigation of bax, bcl-2, bcl-x and p53 gene polymorphisms in multiple sclerosis.
Kuhlmann T, Glas M, zum Bruch C, Mueller W, Weber A, Zipp F, Brück W. Kuhlmann T, et al. J Neuroimmunol. 2002 Aug;129(1-2):154-60. doi: 10.1016/s0165-5728(02)00167-4. J Neuroimmunol. 2002. PMID: 12161031
We identified so far unpublished sequence alterations in the promotor region of the bxl-x gene, in exon 7 of the p53 gene, and in exon 1 of the bax gene. No differences were observed between MS patients and controls. Additional known polymorphisms were …
We identified so far unpublished sequence alterations in the promotor region of the bxl-x gene, in exon 7 of the p53 gene, and …
Target gene therapy of glioma: overexpression of BAX gene under the control of both tissue-specific promoter and hypoxia-inducible element.
Huang J, Gao J, Lv X, Li G, Hao D, Yao X, Zhou L, Liu D, Wang R. Huang J, et al. Acta Biochim Biophys Sin (Shanghai). 2010 Apr;42(4):274-80. doi: 10.1093/abbs/gmq016. Acta Biochim Biophys Sin (Shanghai). 2010. PMID: 20383466 Free article.
Glioma-specific transcription of tumor-killing genes has been exploited as a promising gene therapeutic modality in glioma patients. ...We constructed 4optHBS-Msi1/GFAP promoters and tested their ability to mediate BAX expression to induce apoptosis in glioma …
Glioma-specific transcription of tumor-killing genes has been exploited as a promising gene therapeutic modality in glioma pat …
Apoptosis-promoting gene (bax) transfer potentiates sensitivity of squamous cell carcinoma to cisplatin in vitro and in vivo.
Sugimoto C, Fujieda S, Seki M, Sunaga H, Fan GK, Tsuzuki H, Borner C, Saito H, Matsukawa S. Sugimoto C, et al. Int J Cancer. 1999 Sep 9;82(6):860-7. doi: 10.1002/(sici)1097-0215(19990909)82:6<860::aid-ijc15>3.0.co;2-6. Int J Cancer. 1999. PMID: 10446454 Free article.
To investigate the role of bax gene expression in modulating cisplatin (CDDP)-induced apoptosis in vitro, an established CDDP-resistant human head and neck SCC (IMC-3 cell line) was transfected with bax gene-bearing mammalian expression vector. ...In a …
To investigate the role of bax gene expression in modulating cisplatin (CDDP)-induced apoptosis in vitro, an established CDDP- …
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.
Rampino N, Yamamoto H, Ionov Y, Li Y, Sawai H, Reed JC, Perucho M. Rampino N, et al. Science. 1997 Feb 14;275(5302):967-9. doi: 10.1126/science.275.5302.967. Science. 1997. PMID: 9020077
More than 50 percent (21 out of 41) of human MMP+ colon adenocarcinomas examined were found to have frameshift mutations in a tract of eight deoxyguanosines [(G)8] within BAX, a gene that promotes apoptosis. These mutations were absent in MMP- tumors and were signif …
More than 50 percent (21 out of 41) of human MMP+ colon adenocarcinomas examined were found to have frameshift mutations in a tract of eight …
Involvement of the Bcl2 gene family in the signaling and control of retinal ganglion cell death.
Nickells RW, Semaan SJ, Schlamp CL. Nickells RW, et al. Prog Brain Res. 2008;173:423-35. doi: 10.1016/S0079-6123(08)01129-1. Prog Brain Res. 2008. PMID: 18929125 Review.
Perhaps the most critical molecule at play is the pro-apoptotic protein BAX. Without BAX, ganglion cell somas appear to survive an optic nerve insult indefinitely. ...Interacting with BAX are other members of this larger gene family, including the anti …
Perhaps the most critical molecule at play is the pro-apoptotic protein BAX. Without BAX, ganglion cell somas appear to surviv …
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