Synthesis of 3,4,7,8-tetrahydronaphthalene-1,5(2H,6H)-dione

Garrett B Minne; Pierre J De Clercq

doi:10.3390/12020183

Synthesis of 3,4,7,8-tetrahydronaphthalene-1,5(2H,6H)-dione

Molecules. 2007 Feb 13;12(2):183-7. doi: 10.3390/12020183.

Authors

Garrett B Minne¹, Pierre J De Clercq

Affiliation

¹ Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan 281 (S4), B-9000 Gent, Belgium.

Abstract

A short and high yielding route for the preparation of the title compound, starting from commercially available 1,5-dihydroxynaphthalene, is described. The key step in the sequence is the air oxidation of a bis(trimethylsilyloxy)diene precursor.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, Thin Layer
Molecular Structure
Tetrahydronaphthalenes / chemical synthesis*
Tetrahydronaphthalenes / chemistry

Substances

Tetrahydronaphthalenes