The effect of β-1,3-glucan on the photosynthetic apparatus and oxidative stress parameters of tomato (Lycopersicon esculentum Mill., cv. Tamara) leaves under fusarium wilt caused artificially by the fungal pathogen Fusarium oxysporum sp. was studied in 2-month-old tomato plants. Infection of tomato plants with a pathogen causes activation of lipid peroxidation (LPO) processes in leaves and significant changes in the photosynthetic apparatus, which is reflected in a decrease in the chlorophyll (Chl) a and Chl a/Chl b ratio and carotenoid content, disturbances in the absorption and utilisation of light energy in PSII. Pretreatment of plants with β-1,3-glucan contributes to the stabilisation of LPO and normalises the level of a photosynthetic pigments and a course of photochemical processes in the chloroplasts of infected leaves, which indicates the protective activity of a drug.