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2019 3
2020 2
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Page 1
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C. Carreras-Sureda A, et al. Among authors: bustos g. Nat Cell Biol. 2019 Jun;21(6):755-767. doi: 10.1038/s41556-019-0329-y. Epub 2019 May 20. Nat Cell Biol. 2019. PMID: 31110288 Free PMC article.
Complex I and II are required for normal mitochondrial Ca2+ homeostasis.
Jaña F, Bustos G, Rivas J, Cruz P, Urra F, Basualto-Alarcón C, Sagredo E, Ríos M, Lovy A, Dong Z, Cerda O, Madesh M, Cárdenas C. Jaña F, et al. Among authors: bustos g. Mitochondrion. 2019 Nov;49:73-82. doi: 10.1016/j.mito.2019.07.004. Epub 2019 Jul 13. Mitochondrion. 2019. PMID: 31310854 Free PMC article.
Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum-to-mitochondria Ca2+ transfer for survival.
Cardenas C, Lovy A, Silva-Pavez E, Urra F, Mizzoni C, Ahumada-Castro U, Bustos G, Jaňa F, Cruz P, Farias P, Mendoza E, Huerta H, Murgas P, Hunter M, Rios M, Cerda O, Georgakoudi I, Zakarian A, Molgó J, Foskett JK. Cardenas C, et al. Among authors: bustos g. Sci Signal. 2020 Jul 14;13(640):eaay1212. doi: 10.1126/scisignal.aay1212. Sci Signal. 2020. PMID: 32665411 Free PMC article.
Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression.
Erices R, Cubillos S, Aravena R, Santoro F, Marquez M, Orellana R, Ramírez C, González P, Fuenzalida P, Bravo ML, Oliva B, Kato S, Ibañez C, Brañes J, Bravo E, Alonso C, García K, Arab C, Torres VA, Godoy AS, Pereira J, Bustos G, Cardenas JC, Cuello MA, Owen GI. Erices R, et al. Among authors: bustos g. Oncotarget. 2017 Mar 28;8(13):20865-20880. doi: 10.18632/oncotarget.15348. Oncotarget. 2017. PMID: 28209916 Free PMC article.
FR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathway.
Urra FA, Muñoz F, Córdova-Delgado M, Ramírez MP, Peña-Ahumada B, Rios M, Cruz P, Ahumada-Castro U, Bustos G, Silva-Pavez E, Pulgar R, Morales D, Varela D, Millas-Vargas JP, Retamal E, Ramírez-Rodríguez O, Pessoa-Mahana H, Pavani M, Ferreira J, Cárdenas C, Araya-Maturana R. Urra FA, et al. Among authors: bustos g. Sci Rep. 2018 Sep 4;8(1):13190. doi: 10.1038/s41598-018-31367-9. Sci Rep. 2018. PMID: 30181620 Free PMC article.
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