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Development and validation of LC-MS/MS methods for the simultaneous quantification of sofosbuvir and its major metabolite (GS-331007) in blood plasma and cerebrospinal and seminal fluid: Application to a pilot clinical trial with a focus on Zika.
Vilhena LS, de Azevedo da Silva AC, Dias da Silva DM, Pinto DP, Coelho EF, de Araújo JFGM, da Silveira GPE, Pereira HM, da Silva LSFV, Estrela Marins RCE, Bortolini RG, Souza TML, Dos Santos VGV, de Assis Nascimento V, Amendoeira FC, da Fonseca LB. Vilhena LS, et al. Biomed Chromatogr. 2023 May;37(5):e5606. doi: 10.1002/bmc.5606. Epub 2023 Mar 5. Biomed Chromatogr. 2023. PMID: 36797051 Clinical Trial.
Atazanavir Is a Competitive Inhibitor of SARS-CoV-2 Mpro, Impairing Variants Replication In Vitro and In Vivo.
Chaves OA, Sacramento CQ, Ferreira AC, Mattos M, Fintelman-Rodrigues N, Temerozo JR, Vazquez L, Pinto DP, da Silveira GPE, da Fonseca LB, Pereira HM, Carlos AS, d'Avila JC, Viola JPB, Monteiro RQ, Bozza PT, Castro-Faria-Neto HC, Souza TML. Chaves OA, et al. Among authors: da silveira gpe. Pharmaceuticals (Basel). 2021 Dec 24;15(1):21. doi: 10.3390/ph15010021. Pharmaceuticals (Basel). 2021. PMID: 35056078 Free PMC article.