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Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.
Lamoot A, Jangra S, Laghlali G, Warang P, Singh G, Chang LA, Park SC, Singh G, De Swarte K, Zhong Z, Louage B, De Lombaerde E, Ye T, Chen Y, Cuadrado-Castano S, Lienenklaus S, Sanders NN, Lambrecht BN, García-Sastre A, Schotsaert M, De Geest BG. Lamoot A, et al. Among authors: laghlali g. Small. 2024 Mar;20(10):e2306892. doi: 10.1002/smll.202306892. Epub 2023 Oct 22. Small. 2024. PMID: 37867244
A multicomponent intranasal adjuvant drives durable humoral, cellular, and mucosal immune responses to SARS-CoV-2 in young and aged mice.
Jangra S, Landers JJ, Laghlali G, Rathnasinghe R, O'Konek JJ, Janczak KW, García-Sastre A, Baker JR Jr, Schotsaert M, Wong PT. Jangra S, et al. Among authors: laghlali g. Res Sq [Preprint]. 2023 Jan 20:rs.3.rs-2457013. doi: 10.21203/rs.3.rs-2457013/v1. Res Sq. 2023. PMID: 36711479 Free PMC article. Updated. Preprint.
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*.
Jangra S, De Vrieze J, Choi A, Rathnasinghe R, Laghlali G, Uvyn A, Van Herck S, Nuhn L, Deswarte K, Zhong Z, Sanders NN, Lienenklaus S, David SA, Strohmeier S, Amanat F, Krammer F, Hammad H, Lambrecht BN, Coughlan L, García-Sastre A, De Geest BG, Schotsaert M. Jangra S, et al. Among authors: laghlali g. Angew Chem Int Ed Engl. 2021 Apr 19;60(17):9467-9473. doi: 10.1002/anie.202015362. Epub 2021 Mar 11. Angew Chem Int Ed Engl. 2021. PMID: 33464672 Free PMC article.
Enhanced mucosal B- and T-cell responses against SARS-CoV-2 after heterologous intramuscular mRNA prime/intranasal protein boost vaccination with a combination adjuvant.
Laghlali G, Wiest MJ, Karadag D, Warang P, O'Konek JJ, Chang LA, Park S, Farazuddin M, Landers JJ, Janczak KW, García-Sastre A, Baker JR, Wong PT, Schotsaert M. Laghlali G, et al. bioRxiv [Preprint]. 2024 Mar 29:2024.03.28.587260. doi: 10.1101/2024.03.28.587260. bioRxiv. 2024. PMID: 38586014 Free PMC article. Preprint.
12 results