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Page 1
Carboxylesterase 2a deletion provokes hepatic steatosis and insulin resistance in mice involving impaired diacylglycerol and lysophosphatidylcholine catabolism.
Mol Metab. 2023 Jun;72:101725. doi: 10.1016/j.molmet.2023.101725. Epub 2023 Apr 12.
Mol Metab. 2023.
PMID: 37059417
Free PMC article.
Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes.
Grabner GF, Guttenberger N, Mayer N, Migglautsch-Sulzer AK, Lembacher-Fadum C, Fawzy N, Bulfon D, Hofer P, Züllig T, Hartig L, Kulminskaya N, Chalhoub G, Schratter M, Radner FPW, Preiss-Landl K, Masser S, Lass A, Zechner R, Gruber K, Oberer M, Breinbauer R, Zimmermann R.
Grabner GF, et al. Among authors: chalhoub g.
J Am Chem Soc. 2022 Apr 13;144(14):6237-6250. doi: 10.1021/jacs.1c10836. Epub 2022 Apr 1.
J Am Chem Soc. 2022.
PMID: 35362954
Free PMC article.
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Lipid droplet-mitochondria coupling via perilipin 5 augments respiratory capacity but is dispensable for FA oxidation.
Kien B, Kolleritsch S, Kunowska N, Heier C, Chalhoub G, Tilp A, Wolinski H, Stelzl U, Haemmerle G.
Kien B, et al. Among authors: chalhoub g.
J Lipid Res. 2022 Mar;63(3):100172. doi: 10.1016/j.jlr.2022.100172. Epub 2022 Jan 21.
J Lipid Res. 2022.
PMID: 35065923
Free PMC article.
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Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease.
Chalhoub G, Kolleritsch S, Maresch LK, Taschler U, Pajed L, Tilp A, Eisner H, Rosina P, Kien B, Radner FPW, Schicho R, Oberer M, Schoiswohl G, Haemmerle G.
Chalhoub G, et al.
J Lipid Res. 2021;62:100075. doi: 10.1016/j.jlr.2021.100075. Epub 2021 Apr 17.
J Lipid Res. 2021.
PMID: 33872605
Free PMC article.
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Oxidative cyclization of N-methyl-dopa by a fungal flavoenzyme of the amine oxidase family.
Lahham M, Pavkov-Keller T, Fuchs M, Niederhauser J, Chalhoub G, Daniel B, Kroutil W, Gruber K, Macheroux P.
Lahham M, et al. Among authors: chalhoub g.
J Biol Chem. 2018 Nov 2;293(44):17021-17032. doi: 10.1074/jbc.RA118.004227. Epub 2018 Sep 7.
J Biol Chem. 2018.
PMID: 30194285
Free PMC article.
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The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1.
Eisner H, Riegler-Berket L, Gamez CFR, Sagmeister T, Chalhoub G, Darnhofer B, Jazleena PJ, Birner-Gruenberger R, Pavkov-Keller T, Haemmerle G, Schoiswohl G, Oberer M.
Eisner H, et al. Among authors: chalhoub g.
Int J Mol Sci. 2022 Oct 28;23(21):13101. doi: 10.3390/ijms232113101.
Int J Mol Sci. 2022.
PMID: 36361897
Free PMC article.
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