Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1985 1
1987 2
1989 1
1991 3
1992 2
1993 1
1995 1
1998 1
1999 1
2000 1
2001 1
2003 1
2004 1
2005 1
2013 2
2014 1
2016 2
2017 4
2018 1
2019 2
2020 1
2021 2
2022 3
2023 1
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

37 results

Results by year

Filters applied: . Clear all
Page 1
Target specific tight junction modulators.
Brunner J, Ragupathy S, Borchard G. Brunner J, et al. Adv Drug Deliv Rev. 2021 Apr;171:266-288. doi: 10.1016/j.addr.2021.02.008. Epub 2021 Feb 20. Adv Drug Deliv Rev. 2021. PMID: 33617902 Free article. Review.
Intercellular tight junctions represent a formidable barrier against paracellular drug absorption at epithelia (e.g., nasal, intestinal) and the endothelium (e.g., blood-brain barrier). ...
Intercellular tight junctions represent a formidable barrier against paracellular drug absorption at epithelia (e.g., nasal, intestin …
Genetic analysis of potassium transport loci in Escherichia coli: evidence for three constitutive systems mediating uptake potassium.
Dosch DC, Helmer GL, Sutton SH, Salvacion FF, Epstein W. Dosch DC, et al. J Bacteriol. 1991 Jan;173(2):687-96. doi: 10.1128/jb.173.2.687-696.1991. J Bacteriol. 1991. PMID: 1987159 Free PMC article.
Each of these two is absolutely dependent on the product of the trkA gene, a cytoplasmic protein associated with the inner membrane (D. Bossemeyer, A. Borchard, D. C. Dosch, G. C. Helmer, W. Epstein, I. R. Booth, and E. ...
Each of these two is absolutely dependent on the product of the trkA gene, a cytoplasmic protein associated with the inner membrane (D. Boss …
Chitosans for gene delivery.
Borchard G. Borchard G. Adv Drug Deliv Rev. 2001 Nov 5;52(2):145-50. doi: 10.1016/s0169-409x(01)00198-3. Adv Drug Deliv Rev. 2001. PMID: 11718938 Review.
Efficient non-viral gene delivery based on cationic polymers as DNA-condensing agents is dependent on a variety of factors, e.g. complex size, complex stability, toxicity, immunogenicity, protection against DNase degradation, and intracellular trafficking and processing of …
Efficient non-viral gene delivery based on cationic polymers as DNA-condensing agents is dependent on a variety of factors, e.g. comp …
Non-covalent modification of granulocyte-colony stimulating factor (G-CSF) by coiled-coil technology.
Reichert C, Perozzo R, Borchard G. Reichert C, et al. Int J Pharm. 2016 Sep 10;511(1):98-103. doi: 10.1016/j.ijpharm.2016.06.122. Epub 2016 Jun 27. Int J Pharm. 2016. PMID: 27363936
We present here an approach to non-covalently combine an engineered model protein with a PEGylated peptide via coiled-coil binding. To this end a fusion protein of G-CSF and the peptide sequence (JunB) was created-one sequence of JunB was expressed at the N-terminal of GCS …
We present here an approach to non-covalently combine an engineered model protein with a PEGylated peptide via coiled-coil binding. To this …
Differences between intravenous iron products: focus on treatment of iron deficiency in chronic heart failure patients.
Martin-Malo A, Borchard G, Flühmann B, Mori C, Silverberg D, Jankowska EA. Martin-Malo A, et al. ESC Heart Fail. 2019 Apr;6(2):241-253. doi: 10.1002/ehf2.12400. Epub 2019 Jan 29. ESC Heart Fail. 2019. PMID: 30694615 Free PMC article. Review.
All i.v. iron complexes consist of a polynuclear Fe(III)-oxyhydroxide/oxide core that is stabilized with a compound-specific carbohydrate, which strongly influences their physico-chemical properties (e.g. molecular weight distribution, complex stability, and labile iron co …
All i.v. iron complexes consist of a polynuclear Fe(III)-oxyhydroxide/oxide core that is stabilized with a compound-specific carbohydrate, w …
A Methodological Safe-by-Design Approach for the Development of Nanomedicines.
Schmutz M, Borges O, Jesus S, Borchard G, Perale G, Zinn M, Sips ÄAJAM, Soeteman-Hernandez LG, Wick P, Som C. Schmutz M, et al. Front Bioeng Biotechnol. 2020 Apr 2;8:258. doi: 10.3389/fbioe.2020.00258. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 32300587 Free PMC article.
The EU's NANoREG project and further on the H2020 ProSafe initiative, NanoReg2, and CALIBRATE projects have developed a general SbD approach for nanotechnologies (e.g., paints, textiles, etc.). Based on it, the GoNanoBioMat project elaborated a methodological SbD approach …
The EU's NANoREG project and further on the H2020 ProSafe initiative, NanoReg2, and CALIBRATE projects have developed a general SbD approach …
Impact of peptide permeation enhancer on tight junctions opening cellular mechanisms.
Brunner J, Schvartz D, Gouiller A, Hainard A, Borchard G. Brunner J, et al. Biochem Biophys Rep. 2022 Oct 27;32:101375. doi: 10.1016/j.bbrep.2022.101375. eCollection 2022 Dec. Biochem Biophys Rep. 2022. PMID: 36324528 Free PMC article.
Although L-R5 did not show any in vitro cytotoxicity, a proteomics study revealed that L-R5 interferes with other regulatory pathways, e.g., apoptosis and immune response. We suggest that structural modification of the peptide may increase the specificity TJ protein-peptid …
Although L-R5 did not show any in vitro cytotoxicity, a proteomics study revealed that L-R5 interferes with other regulatory pathways, e. …
Inhibition of G protein-coupled and ATP-sensitive potassium currents by 2-methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015), an amiodarone derivative.
Brandts B, Borchard R, Macianskiene R, Gendviliene V, Dirkmann D, Van Bracht M, Prull M, Meine M, Wickenbrock I, Mubagwa K, Trappe HJ. Brandts B, et al. J Pharmacol Exp Ther. 2004 Jan;308(1):134-42. doi: 10.1124/jpet.103.057646. Epub 2003 Oct 20. J Pharmacol Exp Ther. 2004. PMID: 14569071
2-Methyl-3- (3,5-diiodo-4-carboxymethoxybenzyl) benzofuran (KB130015; KB), a novel compound derived from amiodarone, has been proposed to have antiarrhythmic properties. Its effect on the G protein-coupled inward rectifying K+ current [IK(ACh) or IK(Ado)], ATP-sensitive K+ …
2-Methyl-3- (3,5-diiodo-4-carboxymethoxybenzyl) benzofuran (KB130015; KB), a novel compound derived from amiodarone, has been proposed to ha …
37 results