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Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replication of (5'S)-8,5'-cyclopurine-2'-deoxynucleosides in vitro by DNA polymerase IV, exo-free Klenow fragment, and Dpo4.
Pednekar V, Weerasooriya S, Jasti VP, Basu AK. Pednekar V, et al. Chem Res Toxicol. 2014 Feb 17;27(2):200-10. doi: 10.1021/tx4002786. Epub 2014 Jan 16. Chem Res Toxicol. 2014. PMID: 24392701 Free PMC article.
Both S-cdA T and S-cdA G substitutions occurred in equal frequency in wild-type E. coli, but the frequency of S-cdA G dropped in pol IV-deficient strain, especially when being SOS induced. This suggests that pol IV plays a role in S-cdA G mutations. MF …
Both S-cdA T and S-cdA G substitutions occurred in equal frequency in wild-type E. coli, but the frequency of S-cdA G d …
Human infection with Wuchereria bancrofti in Matara, Sri Lanka: the use, in parallel, of an ELISA to detect filaria-specific IgG4 in urine and of ICT card tests to detect filarial antigen in whole blood.
Weerasooriya MV, Itoh M, Mudalige MP, Qiu XG, Kimura E, Gunawardena NK, Fujimaki Y. Weerasooriya MV, et al. Ann Trop Med Parasitol. 2003 Mar;97(2):179-85. doi: 10.1179/000349803235001624. Ann Trop Med Parasitol. 2003. PMID: 12803873
However, far more of the subjects were found ELISA-positive than ICT-positive (76.5% v. 31.1%). The youngest children studied (aged 1-10 years) were similar to the adult subjects in terms of the prevalence of antigenaemia (33.8%) and the prevalence (72.1%) and concentratio …
However, far more of the subjects were found ELISA-positive than ICT-positive (76.5% v. 31.1%). The youngest children studied (aged 1 …